Synthesis and analgesic activity of some side-chain modified anpirtoline derivatives

Archiv der Pharmazie

Volumn 333, Issue 5, 2000, Pages 107-112

  Rádl, Stanislav ^a   Hezky, Petr ^a   Proška, Jan ^a   Hejnová, Lucie ^a   Krejcí, Ivan ^a  

^a Research Institute of Pharmacy and Biochemistry Prague   (Czech Republic)

Author keywords

(Hetero)aroylpiperazines; 5 HT(1A) receptor ligands; 5 HT(1B) receptor ligands; (Hetero)arylmethyl piperazines; (Hetero)arylsulfanyI methylpiperidines; (Hetero)arylsulfanyl methylp yrrolidines; Analgesi c activity; Anpirtoline analogs

Indexed keywords

1 (3 CHLOROBENZOYL)PIPERAZINE; 1 (3 CHLOROBENZYL) 4 ETHOXYCARBONYLPIPERAZINE; 1 (3 CHLOROBENZYL) 4 METHYLPIPERAZINE; 1 (3 CHLOROBENZYL)PIPERAZINE; 1 (6 CHLOROPYRIDINE 2 CARBONYL) 4 METHYLPIPERAZINE; 1 (6 CHLOROPYRIDINE 2 YLMETHYL) 4 METHYLPIPERAZINE; 2 CHLORO 6 (1 METHYLPIPERIDIN 2 YLMETHYLSULFANYL)PYRIDINE; 2 CHLORO 6 (1 METHYLPIPERIDIN 3 YLMETHYLSULFANYL)PYRIDINE TOSYLATE; 2 CHLORO 6 (1 METHYLPYRROLIDIN 3 YLMETHYLSULFANYL)PYRIDINE TOSYLATE; 2 CHLORO 6 (PIPERIDIN 2 YLMETHYLSULFANYL)PYRIDINE; 2 CHLORO 6 (PIPERIDIN 3 YLMETHYLSULFANYL)PYRIDINE; 2 CHLORO 6 (PYRROLIDIN 3 YLMETHYLSULFANYL)PYRIDINE; 3 (3 CHLOROPHENYLSULFANYL) 8 METHYL 8 AZABICYCLO[3.2.1]OCTANE; 3 (3 CHLOROPHENYLSULFANYLMETHYL) 1 METHYLPIPERIDINE; 3 (3 CHLOROPHENYLSULFANYLMETHYL) 1 METHYLPYRROLIDINE; 3 (3 CHLOROPHENYLSULFANYLMETHYL)PIPERIDINE; 3 (3 CHLOROPHENYLSULFANYLMETHYL)PYRROLIDINE; 3 (6 CHLOROPYRIDIN 2 YLSULFANYL) 8 METHYL 8 AZABICYCLO[3.2.1]OCTANE; ACETIC ACID; ANALGESIC AGENT; ANPIRTOLINE; ANPIRTOLINE DERIVATIVE; SEROTONIN 1A RECEPTOR; SEROTONIN 1B RECEPTOR; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HOT PLATE TEST; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; WRITHING TEST;

ANALGESICS; ANIMALS; BINDING, COMPETITIVE; BRAIN; MALE; MICE; MICE, INBRED STRAINS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PAIN MEASUREMENT; PIPERIDINES; PROTEIN BINDING; PYRIDINES; PYRROLIDINES; RATS; RECEPTORS, SEROTONIN;

EID: 0343729420     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4184(20005)333:5<107::AID-ARDP107>3.0.CO;2-Y     Document Type: Article

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