Hormone replacement therapy and circulating ICAM-1 in postmenopausal women. A randomised controlled trial

Thrombosis and Haemostasis

Volumn 81, Issue 5, 1999, Pages 673-675

  Scarabin, Pierre Yves ^a   Alhenc Gelas, Martine ^a   Oger, Emmanuel ^b   Plu Bureau, Geneviève ^b  

^a HÔPITAL BROUSSAIS   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; FIBRINOGEN; INTERCELLULAR ADHESION MOLECULE 1; MARKER; PROGESTERONE;

ADULT; ARTICLE; ATHEROSCLEROSIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY RISK; FEMALE; FIBRINOGEN BLOOD LEVEL; HEART PROTECTION; HORMONE SUBSTITUTION; HUMAN; HUMAN EXPERIMENT; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; POSTMENOPAUSE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TRANSDERMAL DRUG ADMINISTRATION;

EID: 0343632564     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1614551     Document Type: Article

References (21)

1. Mosca L, Manson JE, Sutherland SE, Langer RD, Manolio T, Barrett-Connor E. Cardiovascular disease in women. A statement for heathcare professionals from the American Heart Association. Circulation 1997; 96: 2468-82.
2. Scarabin PY, Plu-Bureau G, Bara L, Bonithon-Kopp C, Guize L, Samama MM. Haemostatic variables and menopausal status : influence of hormone replacement therapy. Thromb Haemost 1993; 70: 584-7.
3. Guetta V, Cannon III RO. Cardiovascular effects of estrogen and lipid-lowering therapies in postmenopausal women. Circulation 1996; 93: 1928-37.
4. Koh KK, Mincemoyer R, Bui MN, Csako G, Pucino F, Guetta V, Waclawiw M, Cannon RO. Effets of hormone replacement therapy on fibrinolysis in postmenopausal women. N Engl J Med 1997; 336: 683-90.
5. Berliner JA, Navab M, Fogelman AM, Frank JS, Demer LL, Edwards PA, Watson AD, Lusis AJ. Atherosclerosis: basic mechanisms, oxidation, inflammation, and genetics. Circulation 1995; 91: 2488-96.
6. Hwang SJ, Ballantyne CM, Sharrett AR, Smith LC, Davis CE, Gotto AM, Boerwinkle E. Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases. The Atherosclerosis Risk In Communities (ARIC) Study. Circulation 1997; 96: 4219-25.
7. Ridker PM, Hennekens CH, Roitman-Johnson B, Stampfer MJ, Allen J. Plasma concentration of soluble intercellular adhesion molecule 1 and risks of future myocardial infarction in apparently healthy men. Lancet 1998; 351 :88-92.
8. Blann AD, Seigneur M, Steiner M, Miller JP, McCollum CN. Circulating ICAM-1 and VCAM-1 in peripheral artery disease and hypercholesterolemia: relationship to the location of atherosclerotic disease, smoking, and in the prediction of adverse events. Thromb Haemost 1998; 79: 1080-5.
9. Caulin-Glaser T, Watson CA, Pardi R, Bender JR. Effects of 17β-estradiol on cytokine-induced endothelial cell adhesion molecule expression. J Clin Invest 1996; 98: 36-42.
10. Scarabin PY, Ahlenc-Gelas M, Plu-Bureau G, Taisne P, Agher R, Aiach M. Effects of oral and transdermal estrogen/progesterone regimens on blood coagulation and fibrinolysis in postmenopausal women. A randomized controlled trial. Arterioscler Thromb Vasc Biol 1997; 17: 3071-8.
11. De Lignieres B, Basdevant A, Thomas G, Thalabard JC, Mercier-Bodart C, Conard J, Guyene TT, Mairon N, Corvol P, Guy-Grand B, Mauvais-Jarvis P, Sitruk-Ware R. Biological effects of estradiol-17β in postmenopausal women: oral versus percutaneous administration. J Clin Endocrinol Metab 1986; 62: 536-41.
12. Clauss A. Gerinnungsphysiologische Schnellmethode zur Bestimmung des Fibrinogen. Acta Haematol 1957; 17: 237-46.
13. Caulin-Glaser T, Farrell WJ, Pfau SE, Zaret B, Bunger K, Setaro J, Brennan JJ, Bender JR, Cleman MW, Cabin HS, Remetz MS. Modulation of circulating cellular adhesion molecules in postmenopausal women. J Am Coll Cardiol 1998; 31: 1555-60.
14. Koh KK, Bui MN, Mincemoyer R, Cannon III RO. Effects of hormone therapy on inflammatory cell adhesion molecules in postmenopausal healthy women. Am J Cardiol 1997; 80: 1505-7.
15. Hulley S, Grady D, Bush T, Furberg C, Herrington D, Riggs B, Vittinghoff E for the Heart and Estrogen/progestin Replacement Study (HERS) Research Group. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. JAMA 1998; 280: 605-13.
16. Oger E, Alhenc-Gelas M, Plu-Bureau G, Mennen L, Guize L, Scarabin PY. Association of circulating ICAM-1 with menopausal status and hormone replacement therapy (submitted).
17. Beato M. Gene regulation by steroid hormones. Cell 1989; 56: 335-44.
18. Ray A, Prefontaine KE, Ray P. Down-modulation of interleukine-6 gene expression by 17β-estradiol by the estrogen receptor. J Biol Chem 1994; 269: 12940-6.
19. Negre-Salvayre A, Pieraggi MT, Mabile L, Salvayre R. Protective effect of 17β-estradiol against the cytotoxicity of minimally oxidized LDL to cultured bovine aortic endothelial cells. Atherosclerosis 1993; 99: 207-17.
20. Sack MN, Rader DJ, Cannon RO. Oestrogen and inhibition of oxidation of low-density lipoproteins in postmenopausal women. Lancet. 1994; 343: 269-70.
21. Marui N, Offermann MK, Swerlick R, Kunsch C, Rosen CA, Ahmad M, Alexander RW, Medford RM. Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. J Clin Invest 1993; 92: 1866-74.