Recombinant human growth hormone enhances tibial growth in peripubertal female rats but not in males

European Journal of Endocrinology

Volumn 142, Issue 5, 2000, Pages 517-523

  Rol De Lama, M A ^a   Perez Romero A ^a   Tresguerres, J A F ^a   Hermanussen, M ^b   Ariznavarreta, C ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b Aschauhof   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN GROWTH HORMONE;

ANIMAL EXPERIMENT; ARTICLE; BONE GROWTH; CATCH UP GROWTH; CONTROLLED STUDY; DRUG EFFECT; FEMALE; GROWTH RATE; GROWTH STIMULATION; LEG LENGTH; MALE; NONHUMAN; PRIORITY JOURNAL; PUBERTY; RAT; SEX DIFFERENCE; STARVATION; TIBIA; WEIGHT GAIN; WEIGHT REDUCTION;

EID: 0343618613     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.0.1420517     Document Type: Article

References (44)

1. Hermanussen M, Rol de Lama MA, Burmeister J & Tresguerres JAF. Mikro-knemometry: an accurate technique of growth measurements in rats. Physiology and Behaviour 1995 58 347-352.
2. Hermanussen M, Rol de Lama MA, Pérez-Romero A, Ariznararreta C, Burmeister J & Tresguerres JAF. Differential catch-up in body weight and bone growth after short-term starvation in rats. Growth Regulation 1996 6 230-237.
3. Tresguerres JAF, Pérez-Romero A, Rol de Lama MA, Granados B,. Hermanussen M & Ariznavarreta C. Minigrowth spurts: influence of sexual hormones and GH. In Frontiers in Endocrinology, vol 10. Puberty: Basic and Clinical Aspects. Eds C Bergada & JA Moguilevsky. Rome, Italy: Ares Sereno Symposia, 1995.
4. Rol de Lama MA, Pérez-Romero A, Hermanussen M, Ariznavarreta C & Tresguerres JAF. Sexual dimorphism in growth as measured by microknemometry: different responses to GH deficiency and exogenous GH administration. Neuroendocrinology 1998 68 210-219.
5. Rol de Lama MA, Pérez-Romero A, Hermanussen M, Ariznavarreta C & Tresguerres JAF. Periodic growth in rats. Annals of Human Biology 1998 25 441-451.
6. Cheek O & Hill DE. Effect of growth hormone on cell and somatic growth. In Handbook of Physiology, vol 4, pp 159-185. Eds E Knobil & E Sawter. Washington DC: American Physiological Society, 1974.
7. Martinez DA, Orth MW, Carr KE, Vanderby Jr R & Vailas AC. Cortical bone growth and maturational changes in dwarf rats induced by recombinant human growth hormone. American Journal of Physiology 1996 270 E51-E59.
8. Isgaard J, Nilsson A, Lindahl A, Jansson JO & Isaksson OGP. Effects of local administration of GH and IGF-I on longitudinal bone growth in rats. American Journal of Physiology 1986 250 E367-E372.
9. Aspenberg P, Hansson LI & Thorngren KG. Modification of bone formation rate by growth hormone, melanocyte-stimulating hormone, and cortisone in the normal rat. Acta Anatomica 1985 121 84-88.
10. Jørgensen PH, Bak B & Andreassen TT. Mechanical properties and biochemical composition of rat cortical femur and tibia after longterm treatment with biosynthetic human growth hormone. Bone 1991 12 353-359.
11. Harel Z & Tannenbaum GS. Long term alterations in growth hormone and insulin secretion after temporary dietary protein restriction in early life in the rat. Pediatric Research 1995 38 747-753.
12. Lanz JK, Donahoe M, Rogers RM & Ontell M. Effects of growth hormone on diaphragmatic recovery from malnutrition. Journal of Applied Physiology 1992 73 801-805.
13. Mosier HD Jr, Dearden LC, Jansons RA & Hill RR. Cartilage sulfacation during catch-up growth after fasting in rats. Endocrinology 1978 102 386-392.
14. Lima L, Arce V, Tresguerres JAF & Devcsa J. Clonidine potentiates the GH response to GHRH in norepinephrine synthesis inhibited rats: evidence for an α2 adrenergic control of hypothalamic release of somatostatin. Neuroendocrinology 1993 57 1155-1166.
15. Ruiz A, Tébar M, Pérez-Romero A, Rol de Lama MA & Sánchez-Criado JE. Serum levels of GH, IGF-I, LH and ovarian steroids in cyclic and RU486-treated rats. Journal of Endocrinological Investigation 1997 20 611-615.
16. Daughaday WH, Mariz IK & Blethen SL. Inhibition of access of bound somatomedin to membrane receptor and immunobinding sites: a comparison of radioreceptor and radioimmunoassay of somatomedin in native and acid-ethanol extracted serum. Journal of Clinical Endocrinology and Metabolism 1980 51 781-788.
17. Daughaday WH, Parker KA, Borowsky S, Trivedi B & Kapadia M. Measurement of somatomedin-related peptides in fetal, neonatal, and maternal rat serum by insulin-like growth factor (IGF)-I radioimmunoassay, IGF-II radioreceptor assay (RRA), and multiplication-stimulating activity RRA after acid-ethanol extraction. Endocrinology 1982 110 575-581.
18. Bang P, Baxter RC, Blum WF, Breier BH, Clemmons DR, Hall K et al. Valid measurements of total IGF concentrations in biological fluids. Recommendations from the 3rd International Symposium on Insulin-like Growth Factors. Endocrinology 1995 136 816-817.
19. Domené H, Krishnamurthi K, Eshet R, Gilad I, Laron Z, Koch I et al. Growth hormone (GH) stimulates insulin-like growth factor-I (IGF-I) and IGF-I-binding protein-3, but not GH receptor gene expression in livers of juvenile rats. Endocrinology 1993 133 675-682.
20. Byatt JC, Staten NR, Salsgiver WJ, Kostele JC & Collier RJ. Stimulation of food intake and weight gain in mature female rats by bovine prolactin and bovine growth hormone. American Journal of Physiology 1993 6 E986-E992.
21. Azain MJ, Roberts TJ, Martin RJ & Kasser TR. Comparison of daily versus continuous administration of somatotropin on growth rate, feed intake, and body composition in intact female rats. Journal of Animal Science 1995 73 1019-1029.
22. Jansson JO, Alberstsson-Wikland K, Edén S, Thorngren KG & Isaksson O. Effect of frequency of growth hormone administration on longitudinal bone growth and body weight in hypophysectomized rats. Acta Physiologica Scandinavica 1982 114 261-265.
23. Clark RG, Mortensen DL, Carlsson LMS, Spencer SA, McKay P, Mulkerrin M et al. Recombinant human growth hormone (GH)-binding protein enhances the growth-promoting activity of human GH in the rat. Endocrinology 1996 137 4308-4315.
24. Jansson JO, Albertsson-Wikland K, Edén S, Thorngren KG & Isaksson OGP. Circumstantial evidence for a role of the secretory pattern of growth hormone in the control of body growth. Acta Endocrinologica 1982 99 24-30.
25. Cotes PM, Bartlett WA, Gaines Das RE, Flecknell P & Termeer R. Dose regimens of human growth hormone: effects of continuous and of gelatin vehicle on growth in rats and rate of absorption in rabbits. Journal of Endocrinology 1980 87 303-312.
26. Maiter DM, Gabriel SM, Koening JI, Russel E & Martin JB. Sexual differentiation of growth hormone feedback effects on hypothalamic growth hormone-releasing hormone and somatostatin. Neuroendocrinology 1990 51 174-180.
27. Ohashi S, Kaji H, Abe H & Chihara K. Effect of fasting and growth hormone (GH) administration on GH receptor (GHR) messenger ribonucleic acid (mRNA) and GH-binding protein (GHBP) mRNA levels in male rats. Life Science 1995 58 1655-1666.
28. Hizuka N, Takano K, Asakawa K, Sukegawa I, Horikawa R, Kikuchi H et at. Biological action of insulin-like growth factor-1 in vivo. Basic and clinical aspects of growth hormone. Serono Symposia, pp 223-251. Ed BB Bercu. New York: Plenum Press, 1988.
29. Clark RG, Mortenssen DL, Carlsson LM, Carlsson B, Carmignac D & Robinson ICAF. The obese growth hormone (GH)-deficient dwarf rat: body fat responses to patterned delivery of GH and insulin-like growth factor-1. Endocrinology 1996 137 1904-1912.
30. Groesbeck MD, Parlow AF & Daughaday WH. Stimulation of supranormal growth in prepubertal adult plateaued, and hypophysectomized female rats by large doses of rat growth hormone: physiological effects and adverse consequences. Endocrinology 1987 120 1963-1975.
31. Fielder PJ, Mortenssen DL, Mallet P, Carlsson B, Baxter RC & Clark RG. Differential long-term effects of insulin-like growth factor-1 (IGF-1) growth hormone (GH), and IGF-I plus GH on body growth and IGF binding proteins in hypophysectomized rats. Endocrinology 1996 137 1913-1920.
32. Loveridge N, Farquharson C, Palmer R, Lobley GE & Flint DJ. Growth hormone and longitudinal bone growth in vivo: short-term effect of a growth hormone antiserum. Journal of Endocrinology 1995 146 55-52.
33. Flyvbjerg A, Jørgenssen KD, Marshall SM & OØrskov H. Inhibitory effect of octreotide on growth hormone-induced IGF-I generation and organ growth in hypophysectomized rats. American Journal of Physiology 1991 260 E569-E576.
34. Steward CEH & Rotwein P. Growth, differentiation, and survival: multiple physiological functions for insulin-like growth factors. Physiological Reviews 1996 76 1005-1026.
35. Jansson JO, Edén S & Isaksson O. Sexual dimorphism in the control of growth secretion. Endocrine Reviews 1985 6 128-150.
36. Hughes PCR & Tanner JM. A longitudinal study of the growth of the black-hooded rat: methods of measurement and rates of growth for skull, limbs, pelvis, nose-rump and tail lengths. Journal of Anatomy 1970 106 349-370.
37. Ørtoft G, Oxlund H, Jørgenssen PH & Andreassen TT. Glucocorticoid treatment and food deprivation counteract the stimulating effect of growth hormone on rat cortical bone strength. Acta Pædiatrica 1992 81 912-917.
38. O'Sullivan D, Millard WJ, Badger TM, Martin JB & Martin RJ. Growth hormone secretion in genetic large (LL) and small (SS) rats. Endocrinology 1986 119 1948-1953.
39. Ikeda A, Matsuyama S, Nishihara M, Tojo H & Takahashi M. Changes in endogenous growth hormone secretion and onset of puberty in transgenic rats expressing human growth hormone gene. Endocrine Journal 1994 41 523-529.
40. Ikeda A, Chang KT, Matsumoto Y, Furuhata Y, Nishihara M, Sasaki F et al. Obesity and insulin resistance in human growth hormone transgenic rats. Endocrinology 1998 139 3057-3063.
41. Boersma B & Wit JM. Catch-up growth. Endocrine Reviews 1997 18 646-661.
42. Mosier HD Jr. The control of catch-up growth. Acta Endocrinologica 1986 279 (Suppl) 1-7.
43. Phillips LS & Young H. Nutrition and somatomedin I. Effect of fasting and refeeding on serum somatomedin activity and cartilage growth activity in rats. Endocrinology 1976 99 304-314.
44. Froesch ER, Guler HP, Schmid C, Binz K & Zapt J. Therapeutic potential of insulin like growth factor-I. Trends in Endocrinology and Metabolism 1990 1 254-250.