Monoubiquitination is sufficient to signal internalization of the maltose transporter in Saccharomyces cerevisiae

Journal of Bacteriology

Volumn 182, Issue 1, 2000, Pages 241-243

  Lucero, Pilar ^a   Peñalver, Élida ^a   Vela, Laura ^a   Lagunas, Rosario ^a  

^a INSTITUTO DE INVESTIGACIONES BIOMÉDICAS ALBERTO SOLS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; MALTOSE; PERMEASE; UBIQUITIN; URACIL;

ARTICLE; CARBOHYDRATE TRANSPORT; CHEMICAL MODIFICATION; ENDOCYTOSIS; INTERNALIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE; YEAST CELL;

SACCHAROMYCES CEREVISIAE;

EID: 0343593730     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.182.1.241-243.2000     Document Type: Article

References (23)

1. Arnason, T., and M. J. Ellison. 1994. Stress resistance in Saccharomyces cerevisiae is strongly correlated with assembly of a novel type of multiubiquitin chain. Mol. Cell. Biol. 14:7876-7883.
2. Baboshina, O. V., and A. L. Haas. 1996. Novel multiubiquitin chain linkages catalyzed by the conjugating enzymes E2EPF and RAD6 are recognized by 26 S proteasome subunits. J. Biol. Chem. 271:2823-2831.
3. Ciechanover, A. 1998. The ubiquitin-proteasome pathway: on protein death and cell life. EMBO J. 17:7151-7160.
4. Dohmen, J. D., K. Madura, B. Bartel, and A. Varshavsky. 1991. The N-end rule is mediated by the UBC2 (RAD6) ubiquitin-conjugating enzyme. Proc. Natl. Acad. Sci. USA 88:7351-7355.
5. Eckner, D. J., M. Ishaq Khan, J. Marsh, T. R. Butt, and S. T. Crooke. 1987. Chemical synthesis and expression of a cassette adapted ubiquitin gene. J. Biol. Chem. 262:3524-3527.
6. Finley, D., S. Sadis, B. P. Monia, P. Boucher, D. J. Eckner, S. T. Crooke, and V. Chau. 1994. Inhibition of proteolysis and cell cycle progression in a multiubiquitination-deficient yeast mutant. Mol. Cell. Biol. 14:5501-5509.
7. Galan, J. M., and R. Haguenauer-Tsapis. 1997. Ubiquitin Lys63 is involved in ubiquitination of a yeast plasma membrane protein. EMBO J. 16:5847-5854.
8. Hicke, L. 1999. Gettin' down with ubiquitin: turning off cell-surface receptors, transporters and channels. Trends Cell Biol. 9:107-112.
9. Hochstrasser, M., M. J. Ellison, V. Chau, and A. Varshavsky. 1991. The short-lived MATa2 transcriptional regulator is ubiquitinated in vivo. Proc. Natl. Acad. Sci. USA 88:4606-4610.
10. Jentsch, S. 1992. The ubiquitin-conjugation system. Annu. Rev. Genet. 26: 179-207.
11. Johnson, E. S., P. C. M. Ma, I. M. Ota, and A. Varshavsky. 1995. A proteolytic pathway that recognizes ubiquitin as a degradation signal. J. Biol. Chem. 270:17442-17456.
12. Lucero, P., M. Herweijer, and R. Lagunas. 1993. Catabolite inactivation of the yeast maltose transporter is due to proteolysis. FEBS Lett. 333:165-168.
13. Lucero, P., and R. Lagunas. 1997. Catabolite inactivation of the yeast maltose transporter requires ubiquitin-ligase npil/rsp5 and ubiquitin-hydrolase npi2/doa4. FEMS Microbiol. Lett. 147:273-277.
14. Medintz, I., H. Jiang, E. K. Han, W. Cui, and C. A. Michels. 1996. Characterization of the glucose-induced inactivation of maltose permease in Saccharomyces cerevisiae. J. Bacteriol. 178:2245-2254.
15. Medintz, I., H. Jiang, and C. A. Michels. 1998. The role of ubiquitin conjugation in glucose-induced proteolysis of Sacchammyces maltose permease. J. Biol. Chem. 273:34454-34462.
16. Papa, F. R., and M. Hochstrasser. 1993. The yeast DOA4 gene encodes a desubiquitinating enzyme related to a product of the human tre-2 oncogene. Nature 366:313-319.
17. Raths, S., J. Rohrer, F. Crausaz, and H. Riezman. 1993. end3 and end4: two mutants defective in receptor-mediated endocytosis in Saccharomyces cerevisiae. J. Cell Biol. 120:55-65.
18. Riballo, E., M. Herweijer, D. H. Wolf, and R. Lagunas. 1995. Catabolite inactivation of the yeast maltose transporter occurs in the vacuole after internalization by endocytosis. J. Bacteriol. 177:5622-5627.
19. Rodicio, R. 1986. Insertion of non-homologous DNA sequences into a regulatory gene causes a constitutive maltase synthesis in yeast. Curr. Genet. 11:235-241.
20. Schägger, H., and G. von Jagow. 1987. Tricine-sodium dodecyl sulfate-polyacrylamide gel elcctrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal. Biochem. 166:368-379.
21. Spence, J., S. Sadis, A. L. Hass, and D. Finley. 1995. A ubiquitin mutant with specific defects in DNA repair and multiubiquitination. Mol. Cell. Biol. 15:1265-1273.
22. Springael, J. I., J. M. Galan, R. Haguenauer-Tsapis, and B. André. 1999. NH4+-induced down-regulation of the Saccharomyces cerevisiae Gap1p permease involves its ubiquitination with lysine-63-linked chains. J. Cell Sci. 112:1375-1383.
23. Terrell, J., S. Shih, R. Dunn, and L. Hicke. 1998. A function for monoubiquitination in the internalization of a G protein-coupled receptor. Mol. Cell 1:193-202.