A structure-based rationalization of the enantiopreference of subtilisin toward secondary alcohols and isosteric primary amines

Journal of Molecular Catalysis - B Enzymatic

Volumn 3, Issue 1-4, 1997, Pages 65-72

  Kazlauskas, Romas J ^a   Weissfloch, Alexandra N E ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Hydrolase; Enantioselectivity; Lipase; Models; Primary amines; Regioselectivity; Secondary alcohols; Subtilase; Subtilisin

Indexed keywords

ALCOHOLS; AMINES; CRYSTAL STRUCTURE; SYNTHESIS (CHEMICAL); X RAY CRYSTALLOGRAPHY;

ENANTIOMERS; ENANTIOSELECTIVITY; LIPASES; REGIOSELECTIVITY;

ENZYMES;

ALCOHOL; SUBTILISIN; TRIACYLGLYCEROL LIPASE;

ARTICLE; CRYSTAL STRUCTURE; ENANTIOMER; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SYNTHESIS; NONHUMAN; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

EID: 0343196675     PISSN: 13811177     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1381-1177(96)00040-9     Document Type: Article

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