-
1
-
-
0027522225
-
A flow cytometric study of hydrodynamic damage to mammalian cells
-
Al-Rubeai, M., Emery, A.N., Chalder, S. and Goldman, M.H. (1993) A flow cytometric study of hydrodynamic damage to mammalian cells. J. Biotechnol. 31, 161-177.
-
(1993)
J. Biotechnol.
, vol.31
, pp. 161-177
-
-
Al-Rubeai, M.1
Emery, A.N.2
Chalder, S.3
Goldman, M.H.4
-
2
-
-
0022730202
-
Large-scale cell culture in biotechnology
-
Arathoon, W.R. and Birch, J.R. (1986) Large-scale cell culture in biotechnology. Science 232, 1390-1395.
-
(1986)
Science
, vol.232
, pp. 1390-1395
-
-
Arathoon, W.R.1
Birch, J.R.2
-
3
-
-
0026124852
-
Microscopic visualization of insect cell-bubble interactions. I: Rising bubbles, air-medium interface, and the foam layer
-
Bavarian, F., Fan, L.S. and Chalmers, J.J. (1991) Microscopic visualization of insect cell-bubble interactions. I: Rising bubbles, air-medium interface, and the foam layer. Biotechnol. Prog. 7, 140-150.
-
(1991)
Biotechnol. Prog.
, vol.7
, pp. 140-150
-
-
Bavarian, F.1
Fan, L.S.2
Chalmers, J.J.3
-
5
-
-
0002065774
-
Antibody production with airlift fermentors
-
In: Lydersen, B.K. (Eds.), Hanser, New York
-
Birch, J.R., Lambert, K., Thompson, P.W., Kenney, A.C. and Wood, L.A. (1987) Antibody production with airlift fermentors. In: Lydersen, B.K. (Eds.), Large Scale Cell Culture Technology, Hanser, New York, pp. 1-20.
-
(1987)
Large Scale Cell Culture Technology
, pp. 1-20
-
-
Birch, J.R.1
Lambert, K.2
Thompson, P.W.3
Kenney, A.C.4
Wood, L.A.5
-
6
-
-
0026954898
-
Estimation of disruption of animal cells by laminar shear stress
-
Born, C., Zhang, Z., Al-Rubeai, M. and Thomas, C.R. (1992) Estimation of disruption of animal cells by laminar shear stress. Biotechnol. Bioeng. 40, 1004-1010.
-
(1992)
Biotechnol. Bioeng.
, vol.40
, pp. 1004-1010
-
-
Born, C.1
Zhang, Z.2
Al-Rubeai, M.3
Thomas, C.R.4
-
7
-
-
0027475938
-
Gas bubbles bursting at a free surface
-
Boulton-Stone, J.M. and Blake, J.R. (1993) Gas bubbles bursting at a free surface. J. Fluid Mech. 254, 437-466.
-
(1993)
J. Fluid Mech.
, vol.254
, pp. 437-466
-
-
Boulton-Stone, J.M.1
Blake, J.R.2
-
8
-
-
0026124851
-
Microscopic visualization of insect cell-bubble interactions. II: The bubble film and bubble rupture
-
Chalmers, J.J. and Bavarian, F. (1991) Microscopic visualization of insect cell-bubble interactions. II: The bubble film and bubble rupture. Biotechnol. Prog. 7, 151-158.
-
(1991)
Biotechnol. Prog.
, vol.7
, pp. 151-158
-
-
Chalmers, J.J.1
Bavarian, F.2
-
9
-
-
0029256474
-
The protective effect of specific medium additives with respect to bubble rupture
-
Chattopadhyay, D., Rathman, J.F. and Chalmers, J.J. (1995a) The protective effect of specific medium additives with respect to bubble rupture. Biotechnol. Bioeng. 45, 473-480.
-
(1995)
Biotechnol. Bioeng.
, vol.45
, pp. 473-480
-
-
Chattopadhyay, D.1
Rathman, J.F.2
Chalmers, J.J.3
-
10
-
-
0029411978
-
Thermodynamic approach to explain cell adhesion to air-medium interfaces
-
Chattopadhyay, D., Rathman, J.F. and Chalmers, J.J. (1995b) Thermodynamic approach to explain cell adhesion to air-medium interfaces. Biotechnol. Bioeng. 48, 649-658.
-
(1995)
Biotechnol. Bioeng.
, vol.48
, pp. 649-658
-
-
Chattopadhyay, D.1
Rathman, J.F.2
Chalmers, J.J.3
-
11
-
-
0022982950
-
Hydrodynamic effects on cells in agitated tissue culture reactors
-
Cherry, R.S. and Papoutsakis, E.T. (1986) Hydrodynamic effects on cells in agitated tissue culture reactors. Bioprocess Eng. 1, 29-41.
-
(1986)
Bioprocess Eng.
, vol.1
, pp. 29-41
-
-
Cherry, R.S.1
Papoutsakis, E.T.2
-
12
-
-
84988099027
-
Physical mechanisms of cell damage in microcarrier cell culture bioreactors
-
Cherry, R.S. and Papoutsakis, E.T. (1988) Physical mechanisms of cell damage in microcarrier cell culture bioreactors. Biotechnol. Bioeng. 32, 1001-1014.
-
(1988)
Biotechnol. Bioeng.
, vol.32
, pp. 1001-1014
-
-
Cherry, R.S.1
Papoutsakis, E.T.2
-
13
-
-
0002588989
-
Growth and death rates of bovine embryonic kidney cells in turbulent microcarrier bioreactors
-
Cherry, R.S. and Papoutsakis, E.T. (1989) Growth and death rates of bovine embryonic kidney cells in turbulent microcarrier bioreactors. Bioprocess Eng. 4, 81-89.
-
(1989)
Bioprocess Eng.
, vol.4
, pp. 81-89
-
-
Cherry, R.S.1
Papoutsakis, E.T.2
-
15
-
-
0027527774
-
Animal cell culture in stirred bioreactors: Observations on scale-up
-
Chisti, Y. (1993) Animal cell culture in stirred bioreactors: Observations on scale-up. Bioprocess Eng. 9, 191-196.
-
(1993)
Bioprocess Eng.
, vol.9
, pp. 191-196
-
-
Chisti, Y.1
-
16
-
-
0022702156
-
Disruption of microbial cells for intracellular products
-
Chisti, Y. and Moo-Young, M. (1986) Disruption of microbial cells for intracellular products. Enzyme Microb. Technol. 8, 194-204.
-
(1986)
Enzyme Microb. Technol.
, vol.8
, pp. 194-204
-
-
Chisti, Y.1
Moo-Young, M.2
-
17
-
-
0024821348
-
On the calculation of shear rate and apparent viscosity in airlift and bubble column bioreactors
-
Chisti, Y. and Moo-Young, M. (1989) On the calculation of shear rate and apparent viscosity in airlift and bubble column bioreactors. Biotechnol. Bioeng. 34, 1391-1392.
-
(1989)
Biotechnol. Bioeng.
, vol.34
, pp. 1391-1392
-
-
Chisti, Y.1
Moo-Young, M.2
-
18
-
-
0030195477
-
Bioprocess intensification through bioreactor engineering
-
Chisti, Y. and Moo-Young, M. (1996) Bioprocess intensification through bioreactor engineering. Trans. Inst. Chem. Eng. 74A, 575-583.
-
(1996)
Trans. Inst. Chem. Eng.
, vol.74 A
, pp. 575-583
-
-
Chisti, Y.1
Moo-Young, M.2
-
19
-
-
0023846444
-
Liquid circulation in airlift reactors
-
Chisti, Y., Halard, B. and Moo-Young, M. (1988) Liquid circulation in airlift reactors. Chem. Eng. Sci. 43, 451-457.
-
(1988)
Chem. Eng. Sci.
, vol.43
, pp. 451-457
-
-
Chisti, Y.1
Halard, B.2
Moo-Young, M.3
-
20
-
-
0023092907
-
Hydrodynamic effects on animal cells grown in microcarrier cultures
-
Croughan, M.S., Hamel, J.-F. and Wang, D.I.C. (1987) Hydrodynamic effects on animal cells grown in microcarrier cultures. Biotechnol. Bioeng. 29, 130-141.
-
(1987)
Biotechnol. Bioeng.
, vol.29
, pp. 130-141
-
-
Croughan, M.S.1
Hamel, J.-F.2
Wang, D.I.C.3
-
21
-
-
0000376019
-
Design of reactors for plant cells and organs
-
Doran, P.M. (1993) Design of reactors for plant cells and organs. Adv. Biochem. Eng. Biotechnol. 48, 115-168.
-
(1993)
Adv. Biochem. Eng. Biotechnol.
, vol.48
, pp. 115-168
-
-
Doran, P.M.1
-
22
-
-
0028987959
-
Hydrodynamic behaviour of animal cell microcarrier suspensions in split-cylinder airlift bioreactors
-
Ganzeveld, K.J., Chisti, Y. and Moo-Young, M. (1995) Hydrodynamic behaviour of animal cell microcarrier suspensions in split-cylinder airlift bioreactors. Bioprocess Eng. 12, 239-247.
-
(1995)
Bioprocess Eng.
, vol.12
, pp. 239-247
-
-
Ganzeveld, K.J.1
Chisti, Y.2
Moo-Young, M.3
-
23
-
-
0026764943
-
Cell-bubble interactions: Mechanisms of suspended cell damage
-
Garcia-Briones, M.A. and Chalmers, J.J. (1992) Cell-bubble interactions: Mechanisms of suspended cell damage. Ann. N.Y. Acad. Sci. 665, 219-229.
-
(1992)
Ann. N.Y. Acad. Sci.
, vol.665
, pp. 219-229
-
-
Garcia-Briones, M.A.1
Chalmers, J.J.2
-
24
-
-
0028765763
-
Flow parameters associated with hydrodynamic cell injury
-
Garcia-Briones, M.A. and Chalmers, J.J. (1994) Flow parameters associated with hydrodynamic cell injury. Biotechnol. Bioeng. 44, 1089-1098.
-
(1994)
Biotechnol. Bioeng.
, vol.44
, pp. 1089-1098
-
-
Garcia-Briones, M.A.1
Chalmers, J.J.2
-
25
-
-
0028468920
-
Computer simulations of the rupture of a gas bubble at a gas-liquid interface and its implications in animal cell damage
-
Garcia-Briones, M.A., Brodkey, R.S. and Chalmers, J.J. (1994) Computer simulations of the rupture of a gas bubble at a gas-liquid interface and its implications in animal cell damage. Chem. Eng. Sci. 49, 2301-2320.
-
(1994)
Chem. Eng. Sci.
, vol.49
, pp. 2301-2320
-
-
Garcia-Briones, M.A.1
Brodkey, R.S.2
Chalmers, J.J.3
-
26
-
-
0023062018
-
On the evaluation of gas-liquid interfacial effects on hybridoma viability in bubble column bioreactors
-
Handa, A., Emery, A.N. and Spier, R.E. (1987) On the evaluation of gas-liquid interfacial effects on hybridoma viability in bubble column bioreactors. Dev. Biol. Stand. 66, 241-253.
-
(1987)
Dev. Biol. Stand.
, vol.66
, pp. 241-253
-
-
Handa, A.1
Emery, A.N.2
Spier, R.E.3
-
27
-
-
0024654299
-
Effect of gas-liquid interfaces on the growth of suspended mammalian cells: Mechanisms of cell damage by bubbles
-
Handa-Corrigan, A., Emery, A.N. and Spier, R.E. (1989) Effect of gas-liquid interfaces on the growth of suspended mammalian cells: mechanisms of cell damage by bubbles. Enzyme Microb. Technol. 11, 230-235.
-
(1989)
Enzyme Microb. Technol.
, vol.11
, pp. 230-235
-
-
Handa-Corrigan, A.1
Emery, A.N.2
Spier, R.E.3
-
28
-
-
0001061059
-
Use of a spin-filter can reduce disruption of hybridoma cells in a bioreactor
-
Jan, D.C.H., Emery, A.N. and Al-Rubeai, M. (1993) Use of a spin-filter can reduce disruption of hybridoma cells in a bioreactor. Biotechnol. Techniques 7, 351-356.
-
(1993)
Biotechnol. Techniques
, vol.7
, pp. 351-356
-
-
Jan, D.C.H.1
Emery, A.N.2
Al-Rubeai, M.3
-
29
-
-
0026848844
-
Effect of serum concentration on hybridoma viable cell density and production of monoclonal antibodies in CSTRs and on shear sensitivity in air-lift loop reactors
-
Martens, D.E., de Gooijer, C.D., Beuvery, E.C. and Tramper, J. (1992) Effect of serum concentration on hybridoma viable cell density and production of monoclonal antibodies in CSTRs and on shear sensitivity in air-lift loop reactors. Biotechnol. Bioeng. 39, 891-897.
-
(1992)
Biotechnol. Bioeng.
, vol.39
, pp. 891-897
-
-
Martens, D.E.1
De Gooijer, C.D.2
Beuvery, E.C.3
Tramper, J.4
-
31
-
-
0026918490
-
A novel approach to the correlation of mass transfer rates in bubble columns with non-newtonian liquids
-
Merchuk, J.C. and Ben-Zvi (Yona), S. (1992) A novel approach to the correlation of mass transfer rates in bubble columns with non-newtonian liquids. Chem. Eng. Sci. 47, 3517-3523.
-
(1992)
Chem. Eng. Sci.
, vol.47
, pp. 3517-3523
-
-
Merchuk, J.C.1
Ben-Zvi Yona, S.2
-
32
-
-
0029328659
-
Distribution of energy in airlift reactors
-
Merchuk, J.C. and Berzin, I. (1995) Distribution of energy in airlift reactors. Chem. Eng. Sci. 50, 2225-2233.
-
(1995)
Chem. Eng. Sci.
, vol.50
, pp. 2225-2233
-
-
Merchuk, J.C.1
Berzin, I.2
-
33
-
-
0025832590
-
Polyvinyl alcohol and polyethylene glycol as protectants against fluid-mechanical injury of freely-suspended animal cells (CRL 8018)
-
Michaels, J.D. and Papoutsakis, E.T. (1991) Polyvinyl alcohol and polyethylene glycol as protectants against fluid-mechanical injury of freely-suspended animal cells (CRL 8018). J. Biotechnol. 19, 241-258.
-
(1991)
J. Biotechnol.
, vol.19
, pp. 241-258
-
-
Michaels, J.D.1
Papoutsakis, E.T.2
-
34
-
-
0027040632
-
Fluid-mechanical damage of freely-suspended animal cells in agitated bioreactors: Effects of dextran, derivatized celluloses and polyvinyl alcohol
-
Michaels, J.D., Kunas, K.T. and Papoutsakis, E.T. (1992) Fluid-mechanical damage of freely-suspended animal cells in agitated bioreactors: Effects of dextran, derivatized celluloses and polyvinyl alcohol. Chem. Eng. Commun. 118, 341-360.
-
(1992)
Chem. Eng. Commun.
, vol.118
, pp. 341-360
-
-
Michaels, J.D.1
Kunas, K.T.2
Papoutsakis, E.T.3
-
35
-
-
0029347453
-
Analysis of cell-to-bubble attachment in sparged bioreactors in the presence of cell-protecting additives
-
Michaels, J.D., Nowak, J.E., Mallik, A.K., Koczo, K., Wasan, D.T. and Papoutsakis, E.T. (1995a) Analysis of cell-to-bubble attachment in sparged bioreactors in the presence of cell-protecting additives. Biotechnol. Bioeng. 47, 407-419.
-
(1995)
Biotechnol. Bioeng.
, vol.47
, pp. 407-419
-
-
Michaels, J.D.1
Nowak, J.E.2
Mallik, A.K.3
Koczo, K.4
Wasan, D.T.5
Papoutsakis, E.T.6
-
36
-
-
0029347448
-
Interfacial properties of cell culture media with cell-protecting additives
-
Michaels, J.D., Nowak, J.E., Mallik, A.K., Koczo, K., Wasan, D.T. and Papoutsakis, E.T. (1995b) Interfacial properties of cell culture media with cell-protecting additives. Biotechnol. Bioeng. 47, 420-430.
-
(1995)
Biotechnol. Bioeng.
, vol.47
, pp. 420-430
-
-
Michaels, J.D.1
Nowak, J.E.2
Mallik, A.K.3
Koczo, K.4
Wasan, D.T.5
Papoutsakis, E.T.6
-
37
-
-
0027651498
-
A numerical analysis of forces exerted by laminar flow on spreading cells in a parallel plate flow chamber assay
-
Olivier, L.A. and Truskey, G.A. (1993) A numerical analysis of forces exerted by laminar flow on spreading cells in a parallel plate flow chamber assay. Biotechnol. Bioeng. 42, 963-973.
-
(1993)
Biotechnol. Bioeng.
, vol.42
, pp. 963-973
-
-
Olivier, L.A.1
Truskey, G.A.2
-
38
-
-
44949280176
-
Fluid-mechanical damage of animal cells in bioreactors
-
Papoutsakis, E.T. (1991) Fluid-mechanical damage of animal cells in bioreactors. Trends Biotechnol. 9, 427-437.
-
(1991)
Trends Biotechnol.
, vol.9
, pp. 427-437
-
-
Papoutsakis, E.T.1
-
39
-
-
0025513915
-
The role of the plasma membrane fluidity on the shear sensitivity of hybridomas grown under hydrodynamic stress
-
Ramírez, O.T. and Mutharasan, R. (1990) The role of the plasma membrane fluidity on the shear sensitivity of hybridomas grown under hydrodynamic stress. Biotechnol. Bioeng. 36, 911-920.
-
(1990)
Biotechnol. Bioeng.
, vol.36
, pp. 911-920
-
-
Ramírez, O.T.1
Mutharasan, R.2
-
40
-
-
0026609774
-
Effect of serum on the plasma membrane fluidity of hybridomas: An insight into its shear protective mechanism
-
Ramirez, O.T. and Mutharasan, R. (1992) Effect of serum on the plasma membrane fluidity of hybridomas: An insight into its shear protective mechanism. Biotechnol. Prog. 8, 40-50.
-
(1992)
Biotechnol. Prog.
, vol.8
, pp. 40-50
-
-
Ramirez, O.T.1
Mutharasan, R.2
-
41
-
-
0001847619
-
Estimation of effective shear rate for aerated non-Newtonian liquids in airlift bioreactor
-
Shi, L.K., Riba, J.P. and Angelino, H. (1990) Estimation of effective shear rate for aerated non-Newtonian liquids in airlift bioreactor. Chem. Eng. Commun. 89, 25-35.
-
(1990)
Chem. Eng. Commun.
, vol.89
, pp. 25-35
-
-
Shi, L.K.1
Riba, J.P.2
Angelino, H.3
-
42
-
-
0026955781
-
Mechanical agitation of hybridoma suspension cultures: Metabolic effects of serum, Pluronic F68, and albumin supplements
-
Smith, C.G. and Greenfield, P.F. (1992) Mechanical agitation of hybridoma suspension cultures: Metabolic effects of serum, Pluronic F68, and albumin supplements. Biotechnol. Bioeng. 40, 1045-1055.
-
(1992)
Biotechnol. Bioeng.
, vol.40
, pp. 1045-1055
-
-
Smith, C.G.1
Greenfield, P.F.2
-
43
-
-
0022092669
-
Shear stress effects on human embryonic kidney cells in vitro
-
Stathopoulos, N.A. and Hellums, J.D. (1985) Shear stress effects on human embryonic kidney cells in vitro. Biotechnol. Bioeng. 27, 1021-1026.
-
(1985)
Biotechnol. Bioeng.
, vol.27
, pp. 1021-1026
-
-
Stathopoulos, N.A.1
Hellums, J.D.2
-
44
-
-
0342815688
-
Bubble column design for growth of fragile insect cells
-
Tramper, J., Smit, D., Straatman, J. and Vlak, J.M. (1987) Bubble column design for growth of fragile insect cells. Bioprocess Eng. 2, 37-41.
-
(1987)
Bioprocess Eng.
, vol.2
, pp. 37-41
-
-
Tramper, J.1
Smit, D.2
Straatman, J.3
Vlak, J.M.4
-
45
-
-
0028764598
-
Quantification of damage to suspended insect cells as a result of bubble rupture
-
Trinh, K., Garcia-Briones, M., Hink, F. and Chalmers, J.J. (1994) Quantification of damage to suspended insect cells as a result of bubble rupture. Biotechnol. Bioeng. 43, 37-45.
-
(1994)
Biotechnol. Bioeng.
, vol.43
, pp. 37-45
-
-
Trinh, K.1
Garcia-Briones, M.2
Hink, F.3
Chalmers, J.J.4
-
46
-
-
0026617103
-
Effect of low serum concentrations (0-2.5%) on growth, production, and shear sensitivity of hybridoma cells
-
van der Pol, L., Bakker, W.A.M. and Tramper, J. (1992) Effect of low serum concentrations (0-2.5%) on growth, production, and shear sensitivity of hybridoma cells. Biotechnol. Bioeng. 40, 179-182.
-
(1992)
Biotechnol. Bioeng.
, vol.40
, pp. 179-182
-
-
Van Der Pol, L.1
Bakker, W.A.M.2
Tramper, J.3
-
47
-
-
0028329435
-
Unified modelling framework of cell death due to bubbles in agitated and sparged bioreactors
-
Wang, N.S., Yang, J.-D., Calabrese, R.V. and Chang, K.-C. (1994) Unified modelling framework of cell death due to bubbles in agitated and sparged bioreactors. J. Biotechnol. 33, 107-122.
-
(1994)
J. Biotechnol.
, vol.33
, pp. 107-122
-
-
Wang, N.S.1
Yang, J.-D.2
Calabrese, R.V.3
Chang, K.-C.4
-
48
-
-
0028846541
-
Effects of the hydrodynamic environment and shear protectants on survival of erythrocytes in suspension
-
Zhang, Z., Chisti, Y. and Moo-Young, M. (1995) Effects of the hydrodynamic environment and shear protectants on survival of erythrocytes in suspension. J. Biotechnol. 43, 33-40.
-
(1995)
J. Biotechnol.
, vol.43
, pp. 33-40
-
-
Zhang, Z.1
Chisti, Y.2
Moo-Young, M.3
-
49
-
-
0026478845
-
Flow-dependent cytosolic acidification of vascular endothelial cells
-
Ziegelstein, R.C., Cheng, L., Capogrossi, M.C. (1992) Flow-dependent cytosolic acidification of vascular endothelial cells. Science 258, 656-659.
-
(1992)
Science
, vol.258
, pp. 656-659
-
-
Ziegelstein, R.C.1
Cheng, L.2
Capogrossi, M.C.3
|