Effects of differentiation inducers on cell phenotypes of cultured nontransformed and immortalized mammary epithelial cells: A comparative immunocytochemical analysis

Tumor Biology

Volumn 21, Issue 4, 2000, Pages 211-223

  Grünberg, Elke ^a   Eckert, Klaus ^a   Karsten, Uwe ^b   Maurer, H Rainer ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

Adhesion molecules; Cell surface marker molecules; Differentiation inducers; Immunocytochemistry; Mammary epithelial cells; MUC1

Indexed keywords

CALCITRIOL; CARCINOEMBRYONIC ANTIGEN; CELL ADHESION MOLECULE; TRANSFORMING GROWTH FACTOR;

ANTIBODY SPECIFICITY; ARTICLE; BREAST CELL; CELL DIFFERENTIATION; CELL IMMORTALIZATION; CELL SURFACE; CONTROLLED STUDY; EPITHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; PHENOTYPE; PRIORITY JOURNAL;

EID: 0343022323     PISSN: 10104283     EISSN: None     Source Type: Journal    
DOI: 10.1159/000030127     Document Type: Article

References (38)

1. Dairkee S, Held HW: Cytokeratin profile of immunomagnetically separated epithelial subsets of the human mammary gland. In Vitro Cell Dev Biol Anim 1993;29A:427-432.
2. Karsten U, Papsdorf G, Pauly A, Vojtesek B, Moll R, Lane EB, Clausen H, Stosiek P, Kasper M: Subtypes of non-transformed human mammary epithelial cells cultured in vitro: Histo-blood group antigen H type 2 defines basal cell-derived cells. Differentiation 1993;54:55-66.
3. Taylor-Papadimitriou J, Stampfer M, Bartek J, Lewis A, Boshell M, Lane EB, Leigh IM: Keratin expression in human mammary epithelial cells cultured from normal and malignant tissue: Relation to in vivo phenotypes and influences of medium. J Cell Sci 1989;94:403-413.
4. Heatly M, Maxwell P, Whiteside C. Toner P: Cytokeratin intermediate filament expression in benign and malignant breast disease. J Clin Pathol 1995;48:26-32.
5. Eckert K, Fuhrmann-Selter T. Maurer HR: Docetaxel enhances the expression of E-cadherin and carcinoembryonic antigen (CEA) on human colon cancer cell lines in vitro. Anticancer Res 1997;17:7-12.
6. Grünberg E, Eckert K, Maurer HR: Docetaxel treatment of HT-29 colon carcinoma cells reinforces the adhesion and immunocytotoxicity of peripheral blood lymphocytes in vitro. Int J Oncol 1998;12:957-963.
7. Maurer HR, Eckert K, Bissen, MC: Taxotere inhibits the proliferation and induces cell differentiation of HL-60 and K562 human myeloid leukemia cells in vitro. Int J Oncol 1993;3:161-165.
8. Charpin C, Garcia S, Bouvier C, Devictor B, Andrac L, Choux R, Lavaut M: E-cadherin quantitative immunocytochemical assay in breast carconima. J Pathol 1997;181:294-300.
9. Eckert K, Fuhrmann-Selter T, Maurer HR, Büttner P: A colorimetric immunoassay for the detection of E-cadherin and carcinoembryonic antigen (CEA) expression on human colon carcinoma cell lines in vitro. Cancer Lett 1996;105:1-4.
10. Sonnenberg A, Daams H, van der Valk MA, Hilkens J, Hilgers J: Development of mouse mammary gland: Identification of stages in differentiation of lumenal and myoepithelial cells using monoclonal antibodies and polyvalent antiserum against keratin. J Histochcin Cytochem 1986;34:1037-1046.
11. Gioanni J, Le François DL, Zanghellini E, Mazeau C, Ettore F, Lambert JC, Schneider M, Dutrillaux B: Establishment and characterisation of a new tumorigenic cell line with a normal karyotype derived from a human breast adenocarcinoma. Br J Cancer 1990;62:8-13.
12. Karsten U, Widmaier R, Kunde D: Monoclonal antibodies against antigens of the human mammary carcinoma cell line MCF-7. Arch Geschwulstforsch 1983;53:529-536.
13. Oka H, Shiozaki H, Kobayashi K, Inoue M, Tahara H, Kobayashi T, Takatsuka Y, Matsuyshi N, Hirano S, Takeichi M, Mori T: Expression of E-cadherin cell adhesion molecules in human breast cancer tissues and its relationship to metastasis. Cancer Res 1993;53:1696-1701.
14. Ogawa Y, Hirakawa K, Nakata B, Fujihara T, Sawada T, Kato Y, Yoshikawa K, Sowa M: Expression of intercellular adhesion molecule-1 in invasive breast cancer reflects low growth potential, negative lymph node involvement and good prognosis. Clin Cancer Res 1998;4:31-36.
15. Kaufmann M, Heider KH, Sinn HP, von Mickwitz G, Ponta H, Herrlich P: CD44 variant exon epitopes in primary breast cancer and length of survival. Lancet 1995;345:615-619.
16. Bardon S, Razanamahefa L: Retinoic acid suppresses insulin-induced cell growth and cyclin D1 gene expression in human breast cancer cells. Int J Oncol 1998;12:355-359.
17. Chen AC, Guo X, Derguini F, Gudas LJ: Human breast cancer cells and normal mammary epithelial cells: Retinol metabolism and growth inhibition by the retinol metabolite 4-oxoretinol. Cancer Res 1997;57:4642-4651.
18. Hassan HT, Eliopoulos A, Maurer HR, Spandidos DA: Recombinant human GM-CSF enhances the anti-proliferative activity of vitamin D in MCF-7 human breast cancer clonogenic cells. Eur J Cancer 1992;28A: 8-9.
19. Guilbaud NF, Gas N, Dupont MA, Valette A: Effects of differentiation-inducing agents on maturation of human MCF-7 breast cancer cell. J Cell Physiol 1990;145:162-172.
20. Ip MM, Shoemaker SF, Darcy KM: Regulation of rat mammary epithelial cell proliferation and differentiation by tumor necrosis factor-α. Endocrine 1991;130:2833-2844.
21. Mueller H, Flury N, Liu R, Scheidegger S, Eppenberg U: Tumor necrosis factor and interferon are selectively cytostatic in vitro for hormone-dependent and hormonee-independent human breast cancer cells. Eur J Cancer 1996;32A:2311-2318.
22. 3 potentiates the cytotoxic effect of TNF on human breast cancer cells. Mol Cell Endocrinol 1994;106:157-162.
23. Garbin F, Eckert K, Maurer HR: Evaluation of the MTT and SRB assays for testing LAK cell-mediated growth inhibition of various adherent and nonadherent tumor target cells. J Immunol Methods 1994;170: 269-271.
24. Cao Y, Karsten U, Hilgers J: Immunohistochemical characterization of a panel of 56 antibodies with normal human small intestine, colon, and breast tissues. Tumor Biol 1998; 19(suppl 1):88-99.
25. Karsten U, Papsdorf G, Roloff G, Stolley P, Abel H, Walther I, Weiss H: Monoclonal anti-cytokeratin antibody from a hybridoma clone generated by electrofusion. Eur J Cancer Clin Oncol 1985;21:733-740.
26. Karsten U, Pilgrim G, Hanisch F-G, Uhlenbruck G, Kasper M, Stosiek P, Papsdorf G, Pasternak G: A new monoclonal antibody (A46-B/B10) highly specific for the blood group H type 2 epitope: Generation, epitope analysis, serological and histological evaluation. Br J Cancer 1988;58: 176-181.
27. Karsten U, Butschak G, Cao Y, Goletz S, Hanisch F-G: A new monoclonal antibody (A78-G/A7) to the Thomson-Friedenreich pan-tumor antigen. Hybridoma 1995;14:37-44.
28. Butschak G, Harborth J, Osborn M, Karsten U: New monoclonal antibodies recognizing phosphorylated proteins in mitotic cells. Acta Histochemica 1995;97:19-31.
29. Bergtraesser LM, Weitzman SA: Culture of normal and malignant primary human mammary epithelial cells in a physiological manner stimulates in vivo growth patterns and allows discrimination of cell type. Cancer Res 1993;53:2644-2654.
30. Lakhani SR, O'Hare MJ, Monoghan P, Winehouse J, Gazer JC, Sloane JP: Malignant myoepithelioma (myoepithelial carcinoma) of the breast: A detailed cytokeratin study. J Clin Pathol 1995;f48:164-167.
31. Bacus SS, Gudkov AV, Zelnick CR, Chin D, Stern R, Stancovski H, Peles E, Ben-Baruch N, Farbstein H, Lupu R, Wen D, Sela M, Yarden Y: Neu differentiation factor (heregulin) induces expression of intercellular adhesion molecule 1: Implications for many tumors. Cancer Res 1993;53:5251-5261.
32. Zschiesche W, Schönborn I, Behrens J, Herrenknecht K, Hartveit F, Lilleng P, Birchmeier W: Expression of E-cadherin and catenins in invasive mammary carcinomas. Anticancer Res 1997;17:561-568.
33. Theile M, Hartmann S, Scherthan H, Arnold W, Deppert W, Frege R, Glaab F, Haensch W, Scherneck S: Suppression of tumorigenicity of breast cancer cells by transfer of human chromosome 17 does not require transferred BRCA1 and p53 genes. Oncogene 1995;10:439-447.
34. Springer TA, Dustin ML, Kishimoto TK, Marlin SD: The lymphocyte function-associated LFA-1, CD2, and LFA-3 molecules: Cell adhesion receptors of the immune system. Annu Rev Immunol 1987;5:223-252.
35. Marlin SD, Springer TA: Purified intercellular adhesion molecule (ICAM-1) is a ligand for lymphocyte function-associated antigen-1 (LFA-1). Cell 1987;51:813-819.
36. Karsten U, Papsdorf G, Pauly A, Stosiek P, Kasper M, Pasternak G: Patterns of expression of tumor markers on non-transformed human mammary epithelial cells cultured in vitro. Arch Geschwulstforsch 1990;60:103-108.
37. Liu D, Sy MS: Phorbol myristate acetate stimulates the dimerization of CD44 involving a cysteine in the transmembrane domain. J Immunol 1997;159:2702-2711.
38. 3 inhibits the invasive potential of human breast cancer cells in vitro. Clin Exp Metastasis 1994;12:195-202.