메뉴 건너뛰기




Volumn 58, Issue 4, 2000, Pages 273-279

Sequential trimetrexate, 5-fluorouracil and folinic acid are effective and well tolerated in metastatic colorectal carcinoma

Author keywords

5 Fluorouracil; Colorectal carcinoma; First line chemotherapy; Trimetrexate

Indexed keywords

ANTIHISTAMINIC AGENT; CORTICOSTEROID; FLUOROURACIL; FOLINIC ACID; LOPERAMIDE; TRIMETREXATE;

EID: 0342657719     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000012112     Document Type: Article
Times cited : (11)

References (30)
  • 1
    • 0027379619 scopus 로고
    • The chemotherapy of colon cancer can no longer be ignored
    • Cunningham D, Findlay M: The chemotherapy of colon cancer can no longer be ignored. Eur J Cancer 1993;29A:2077-2079.
    • (1993) Eur J Cancer , vol.29 A , pp. 2077-2079
    • Cunningham, D.1    Findlay, M.2
  • 3
    • 0026721532 scopus 로고
    • Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: Evidence in terms of response rate. Advanced colorectal cancer meta-analysis project
    • Anonymous: Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: Evidence in terms of response rate. Advanced Colorectal Cancer Meta-Analysis Project [see comments]. J Clin Oncol 1992;10: 896-903.
    • (1992) J Clin Oncol , vol.10 , pp. 896-903
  • 4
    • 0002484815 scopus 로고
    • A chemotherapeutic approach to colorectal carcinoma
    • Stearns MW Jr (ed). New York, Wiley
    • Kemeny N, Golbey R: A chemotherapeutic approach to colorectal carcinoma: in Stearns MW Jr (ed): Neoplasms of the Colon, Rectum and Anus. New York, Wiley, 1980, pp 156-168.
    • (1980) Neoplasms of the Colon, Rectum and Anus. , pp. 156-168
    • Kemeny, N.1    Golbey, R.2
  • 6
    • 0028219974 scopus 로고
    • Meta-analysis of randomized trials testing the biochemical modulation of fluorouracil by methotrexate in metastatic colorectal cancer. Advanced colorectal cancer meta-analysis project
    • Anonymous: Meta-analysis of randomized trials testing the biochemical modulation of fluorouracil by methotrexate in metastatic colorectal cancer. Advanced Colorectal Cancer Meta-Analysis Project. J Clin Oncol 1994;12: 960-969.
    • (1994) J Clin Oncol , vol.12 , pp. 960-969
  • 7
    • 0025816073 scopus 로고
    • Update on trimetrexate, a folate antagonist with antineoplastic and antiprotozoal properties
    • Lin JT, Bertino JR: Update on trimetrexate, a folate antagonist with antineoplastic and antiprotozoal properties. Cancer Invest 1991;9: 159-172.
    • (1991) Cancer Invest , vol.9 , pp. 159-172
    • Lin, J.T.1    Bertino, J.R.2
  • 8
    • 0018747748 scopus 로고
    • 2,4-diamino-5-methyl-6 - [(3,4,5 - Trimethoxyanilino)methyl]quinazoline (tmq), a potent non-classical folate antagonist inhibitor-1. Effect on dihydrofolate reductase and growth of rodent tumors in vitro and in vivo
    • Bertino JR, Sawicki WL, Moroson BA, Cashmore AR, Elslager EF: 2,4-diamino-5-methyl-6 - [(3,4,5 - trimethoxyanilino)methyl]quinazoline (tmq), a potent non-classical folate antagonist inhibitor-1. Effect on dihydrofolate reductase and growth of rodent tumors in vitro and in vivo. Biochem Pharmacol 1979;28: 1983-1987.
    • (1979) Biochem Pharmacol , vol.28 , pp. 1983-1987
    • Bertino, J.R.1    Sawicki, W.L.2    Moroson, B.A.3    Cashmore, A.R.4    Elslager, E.F.5
  • 9
    • 0021340811 scopus 로고
    • Uptake and efficacy of trimetrexate (TMQ. 2,4-diamino-5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazoline), a non-classical antifolate in methotrexate-resistant leukemia cells in vitro
    • Kamen BA, Eibl B, Cashmore A, Bertino J: Uptake and efficacy of trimetrexate (TMQ. 2,4-diamino-5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazoline), a non-classical antifolate in methotrexate-resistant leukemia cells in vitro. Biochem Pharmacol 1984;33:1697-1699.
    • (1984) Biochem Pharmacol , vol.33 , pp. 1697-1699
    • Kamen, B.A.1    Eibl, B.2    Cashmore, A.3    Bertino, J.4
  • 10
    • 0023640197 scopus 로고
    • Effects of methotrexate and of the 'non-classical' folate antagonist trimetrexate on human leukemia cells
    • Rodenhuis S, McGuire JJ, Sawicki WL, Bertino JR: Effects of methotrexate and of the 'non-classical' folate antagonist trimetrexate on human leukemia cells. Leukemia 1987;1:116-120.
    • (1987) Leukemia , vol.1 , pp. 116-120
    • Rodenhuis, S.1    McGuire, J.J.2    Sawicki, W.L.3    Bertino, J.R.4
  • 11
    • 0023501916 scopus 로고
    • Therapeutic synergy of trimetrexate (CI-898) in combination with doxorubicin, vineristine, cytoxan, 6-thioguanine, cisplatin, or 5-fluorouracil against intraperitoneally implanted P388 leukemia
    • Leopold WR, Dykes DJ, Griswold DP Jr: Therapeutic synergy of trimetrexate (CI-898) in combination with doxorubicin, vineristine, cytoxan, 6-thioguanine, cisplatin, or 5-fluorouracil against intraperitoneally implanted P388 leukemia. NCI Monogr 1987, pp 99-104.
    • (1987) NCI Monogr , pp. 99-104
    • Leopold, W.R.1    Dykes, D.J.2    Griswold D.P., Jr.3
  • 12
    • 0024415638 scopus 로고
    • Sequence and schedule-dependent synergy of trimetrexate in combination with 5-fluorouracil in vitro and in mice
    • Elliott WL, Howard CT, Dykes DJ, Leopold WR: Sequence and schedule-dependent synergy of trimetrexate in combination with 5-fluorouracil in vitro and in mice. Cancer Res 1989; 49:5586-5590.
    • (1989) Cancer Res , vol.49 , pp. 5586-5590
    • Elliott, W.L.1    Howard, C.T.2    Dykes, D.J.3    Leopold, W.R.4
  • 13
    • 0024371816 scopus 로고
    • Sequence-dependent enhancement of HCT-8 cell kill by trimetrexate and fluoropyrimidines: Implications for the mechanism of this interaction
    • Sobrero A, Romanini A, Russello O, Nicolin A, Rosso R, Bertino JR: Sequence-dependent enhancement of HCT-8 cell kill by trimetrexate and fluoropyrimidines: Implications for the mechanism of this interaction. Eur J Cancer Clin Oncol 1989;25:977-982.
    • (1989) Eur J Cancer Clin Oncol , vol.25 , pp. 977-982
    • Sobrero, A.1    Romanini, A.2    Russello, O.3    Nicolin, A.4    Rosso, R.5    Bertino, J.R.6
  • 14
    • 0028323029 scopus 로고
    • Trial of sequential trimetrexate, fluorouracil, and high-dose leucovorin in previously treated patients with gastrointestinal carcinoma
    • Conti JA, Kemeny N, Seiter K, Goker E, Tong W, Andre M, Ragusa K, Bertino JR: Trial of sequential trimetrexate, fluorouracil, and high-dose leucovorin in previously treated patients with gastrointestinal carcinoma. J Clin Oncol 1994;12:695-700.
    • (1994) J Clin Oncol , vol.12 , pp. 695-700
    • Conti, J.A.1    Kemeny, N.2    Seiter, K.3    Goker, E.4    Tong, W.5    Andre, M.6    Ragusa, K.7    Bertino, J.R.8
  • 15
    • 0029968277 scopus 로고    scopus 로고
    • Role of chemotherapy for advanced colorectal cancer: New opportunities
    • Bleiberg H: Role of chemotherapy for advanced colorectal cancer: New opportunities. Semin Oncol 1996;23:42-50.
    • (1996) Semin Oncol , vol.23 , pp. 42-50
    • Bleiberg, H.1
  • 17
    • 0026642174 scopus 로고
    • Leucovorin enhances cytotoxicity of trimetrexate/fluorouracil, but not methotrexate/ fluorouracil, in CCRF-CEM cells
    • Romanini A, Li WW, Colofiore JR, Bertino JR: Leucovorin enhances cytotoxicity of trimetrexate/fluorouracil, but not methotrexate/ fluorouracil, in CCRF-CEM cells. J Natl Cancer Inst 1992;84:1033-1038.
    • (1992) J Natl Cancer Inst , vol.84 , pp. 1033-1038
    • Romanini, A.1    Li, W.W.2    Colofiore, J.R.3    Bertino, J.R.4
  • 18
    • 0025981649 scopus 로고
    • Role of folylpolyglutamates in biochemical modulation of fluoropyrimidines by leucovorin
    • Romanini A, Lin JT, Niedzwiecki D, Bunni M, Priest DG, Bertino JR: Role of folylpolyglutamates in biochemical modulation of fluoropyrimidines by leucovorin. Cancer Res 1991;51: 789-793.
    • (1991) Cancer Res , vol.51 , pp. 789-793
    • Romanini, A.1    Lin, J.T.2    Niedzwiecki, D.3    Bunni, M.4    Priest, D.G.5    Bertino, J.R.6
  • 19
    • 0023521422 scopus 로고
    • Trimetrexate: A second generation folate antagonist in clinical trial
    • Lin JT, Bertino JR: Trimetrexate: A second generation folate antagonist in clinical trial. J Clin Oncol 1987;5:2032-2040.
    • (1987) J Clin Oncol , vol.5 , pp. 2032-2040
    • Lin, J.T.1    Bertino, J.R.2
  • 20
    • 0024385167 scopus 로고
    • The modulation of fluorouracil with leucovorin in metastatic colorectal carcinoma: A prospective randomized phase III trial
    • Gastrointestinal Tumor Study Group [published erratum appears in J Clin Oncol 1990;8:185].
    • Petrelli N, Douglass HO Jr, Herrera L, Russell D, Stablein DM, Bruckner HW, Mayor RJ, Schinella R, Green MD, Muggia FM: The modulation of fluorouracil with leucovorin in metastatic colorectal carcinoma: A prospective randomized phase III trial. Gastrointestinal Tumor Study Group [published erratum appears in J Clin Oncol 1990;8:185]. J Clin Oncol 1989;7:1419-1426.
    • (1989) J Clin Oncol , vol.7 , pp. 1419-1426
    • Petrelli, N.1    Douglass H.O., Jr.2    Herrera, L.3    Russell, D.4    Stablein, D.M.5    Bruckner, H.W.6    Mayor, R.J.7    Schinella, R.8    Green, M.D.9    Muggia, F.M.10
  • 21
    • 0031056423 scopus 로고    scopus 로고
    • Phase II study of trimetrexate, fluorouracil, and leucovorin for advanced colorectal cancer
    • Blanke CD, Kasimis B, Schein P, Capizzi R, Kurman M: Phase II study of trimetrexate, fluorouracil, and leucovorin for advanced colorectal cancer. J Clin Oncol 1997;15:915-920.
    • (1997) J Clin Oncol , vol.15 , pp. 915-920
    • Blanke, C.D.1    Kasimis, B.2    Schein, P.3    Capizzi, R.4    Kurman, M.5
  • 24
    • 0000389059 scopus 로고    scopus 로고
    • Weekly irinotecan (Cpt 11), leucovorin (LV), and fluorouracil (FU) is superior to daily x5 LV/FU in patients with previously untreated metastatic colorectal cancer
    • Saltz LB, Locker PK, Pirotta N, Elfring GL, Miller L: Weekly irinotecan (Cpt 11), leucovorin (LV), and fluorouracil (FU) is superior to daily X5 LV/FU in patients with previously untreated metastatic colorectal cancer. Proc Am Soc Clin Oncol 1999;18:989.
    • (1999) Proc Am Soc Clin Oncol , vol.18 , pp. 989
    • Saltz, L.B.1    Locker, P.K.2    Pirotta, N.3    Elfring, G.L.4    Miller, L.5
  • 25
    • 9044245305 scopus 로고    scopus 로고
    • ZD1694: A novel thymidylate synthase inhibitor with substantial activity in the treatment of patients with advanced colorectal cancer
    • Tomudex Colorectal Study Group
    • Zalcberg JR, Cunningham D, Van Cutsem E, Francois E, Schornagel J, Adenis A, Green M, Iveson A, Azab M, Seymour I: ZD1694: A novel thymidylate synthase inhibitor with substantial activity in the treatment of patients with advanced colorectal cancer. Tomudex Colorectal Study Group. J Clin Oncol 1996;14:716-721.
    • (1996) J Clin Oncol , vol.14 , pp. 716-721
    • Zalcberg, J.R.1    Cunningham, D.2    Van Cutsem, E.3    Francois, E.4    Schornagel, J.5    Adenis, A.6    Green, M.7    Iveson, A.8    Azab, M.9    Seymour, I.10
  • 26
    • 33947153048 scopus 로고
    • 'Tomudex' (ZD1694): Results of a randomised trial in advanced colorectal cancer demonstrate efficacy and reduced mucositis and leucopenia
    • The 'Tomadex' Colorectal Cancer Study Group.
    • Cunningham D, Zalcberg JR, Rath U, Olver I, Van Cutsem E, Svensson C, Seitz JF, Harper P, Kerr D, Perez-Manga G: 'Tomudex' (ZD1694): Results of a randomised trial in advanced colorectal cancer demonstrate efficacy and reduced mucositis and leucopenia. The 'Tomadex' Colorectal Cancer Study Group. Eur J Cancer 1995;31A:1945-1954.
    • (1995) Eur J Cancer , vol.31 A , pp. 1945-1954
    • Cunningham, D.1    Zalcberg, J.R.2    Rath, U.3    Olver, I.4    Van Cutsem, E.5    Svensson, C.6    Seitz, J.F.7    Harper, P.8    Kerr, D.9    Perez-Manga, G.10
  • 28
    • 0041055512 scopus 로고    scopus 로고
    • Randomised multicentre trial of chronotherapy with oxaliplatin, fluorouracil and folinic acid in metastatic colorectal cancer
    • International Organization of Cancer Chronotherapy
    • Levi F, Zidani R, Misset JL: Randomised multicentre trial of chronotherapy with oxaliplatin, fluorouracil and folinic acid in metastatic colorectal cancer. International Organization of Cancer Chronotherapy. Lancet 1997;350:681-686.
    • (1997) Lancet , vol.350 , pp. 681-686
    • Levi, F.1    Zidani, R.2    Misset, J.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.