Regional cerebral glucose metabolism in healthy volunteers determined by fluordeoxyglucose positron emission tomography: Appearance and variance in the transaxial, coronal, and sagittal planes

Clinical Nuclear Medicine

Volumn 25, Issue 8, 2000, Pages 596-602

  Ivançević, Velimir ^a   Alavi, Abass ^b   Souder, Elaine ^b   Mozley, P David ^b   Gur, Raquel E ^b   Bénard, François ^b   Munz, Dieter L ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Brain; Fluorodeoxyglucose; Healthy Volunteers; Positron Emission Tomography; Projection Planes

Indexed keywords

FLUORODEOXYGLUCOSE F 18; GLUCOSE;

ADULT; AGE; AGED; ARTICLE; BASAL GANGLION; BRAIN METABOLISM; CAUDATE NUCLEUS; CEREBELLUM; CINGULATE GYRUS; DIAGNOSTIC VALUE; FEMALE; GLUCOSE METABOLISM; HEMISPHERIC DOMINANCE; HUMAN; HUMAN EXPERIMENT; IMAGE ANALYSIS; MALE; NORMAL HUMAN; OCCIPITAL CORTEX; POSITRON EMISSION TOMOGRAPHY; THALAMUS; VISUAL CORTEX; VOLUNTEER;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ALGORITHMS; ANALYSIS OF VARIANCE; BASAL GANGLIA; BRAIN; CAUDATE NUCLEUS; CEREBELLUM; FEMALE; FLUORODEOXYGLUCOSE F18; FRONTAL LOBE; GLUCOSE; GYRUS CINGULI; HUMANS; IMAGE ENHANCEMENT; IMAGE PROCESSING, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; MALE; MIDDLE AGED; OCCIPITAL LOBE; PARIETAL LOBE; RADIOPHARMACEUTICALS; STATISTICS, NONPARAMETRIC; TEMPORAL LOBE; TOMOGRAPHY, EMISSION-COMPUTED; VISUAL CORTEX;

EID: 0342647324     PISSN: 03639762     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003072-200008000-00005     Document Type: Article

References (22)

1. Duara R, Margolin RA, Robertson-Tchabo EA, et al: Cerebral glucose utilization as measured with positron emission tomography in 21 resting healthy men between the age of 21 and 83 years. Brain 106:761, 1983.
2. Duara R, Grady C, Haxby J, et al: Human brain glucose utilization and cognitive function in relation to age. Ann Neurol 16:703, 1984.
3. DeLeon M, George AE, Tomanelli J, et al: Positron emission tomography studies of normal aging, a replication of PET III and 18-FDG using PET IV and 11-CDG. Neurobiol Aging 8:319, 1987.
4. 18F) fluorodeoxyglucose method. J Cerebr Blood Flow Metab 2:163, 1982.
5. Chawluk J, Alavi A, Hurtig H, et al: Altered patterns of regional cerebral metabglucose metabolism in aging and dementia. J Cerebr Blood Flow Metab 5(Suppl 1):S121, 1985.
6. Chawluk JB, Alavi A, Dann R, et al: Positron emission tomography in aging and dementia: the effect of cerebral atrophy. J Nucl Med 28:431, 1987.
7. Yoshii F, Barker WW, Aracy JY, et al: Sensitivity of cerebral glucose metabolism to age, gender, brain volume, brain atrophy and cerebrovascular risk factors. J Cerebr Blood Flow Metab 8:654, 1988.
8. Alavi A: The aging brain. J Neuropsychiatry 1(Suppl):S51, 1989.
9. Alavi A, Jolles PR, Jamieson DG, et al: Anatomical and functional changes of the brain in normal aging and dementia as demonstrated by MRI, CT and PET. In: Freeman LM, Weissman HS, eds. Nuclear Medicine Annual. New York: Raven Press, 1989, pp 49-79.
10. Weiss DW, Souder E, Alavi A, et al: Effects of aging on whole brain and regional glucose metabolism as assessed by F-18 positron emission tomography. J Nucl Med 31:771P, 1991.
11. Loessner A, Alavi A, Lewandrowski K-U, et al: Regional cerebral function determined by FDG-PET in healthy volunteers: normal patterns and changes with age. J Nucl Med 36:1141, 1994.
12. Moeller JR, Ishikawa T, Dhawan V, et al: The metabolic topography of normal aging. J Cereb Blood Flow Metab 16:385, 1996.
13. Duara R, Barker W, Chang J, et al: Age and sex differences in cerebral glucose consumption measured by PET using [18-F] fluorodeoxyglucose (FDG). J Nucl Med 26:P68, 1985.
14. Mazziotta JC, Phelps ME, Miller J, Kuhl DE: Tomographic mapping of human cerebral metabolism: normal unstimulated state. Neurology 31:503, 1981.
15. Heiss WD, Pawlik G, Herholz K, et al: Regional kinetic constants and cerebral metabolic rate for glucose in normal human volunteers determined by dynamic positron emission tomography of [18F]-2-fluoro-2-deoxy-D-glucose. J Cerebr Blood Flow Metab 4:212, 1984.
16. Fukuyama H, Harada K, Yamauchi H, et al: Coronal reconstruction images of glucose metabolism in Alzheimer's disease. J Neurol Sci 106:128, 1991.
17. 18F) fluoroglucose-deoxyglucose method for the measurement of local cerebral glucose utilization in man. Circ Res 44:127, 1979.
18. Karp JS, Muehllehner G, Mankoff DA, et al: Continuous slice PENN-PET: a positron tomography with volume imaging capability. J Nucl Med 31:617, 1990.
19. Alavi A, Dann R, Chawluk J, et al: Positron emission tomography imaging of regional cerebral glucose metabolism. Semin Nucl Med 16:2, 1986.
20. Chang LT: A method for attenuation correction in radionuclide computed tomography. IEEE Trans Nucl Sci 25:638, 1978.
21. Roberts MP, Hanaway J, Morest DK: Atlas of the Human Brain in Section, 2nd ed. Philadelphia: Lea & Febiger, 1987.
22. Strother SC, Liow J-S, Moeller JR, et al: Absolute quantitation in neurological PET: Do we need it? J Cerebr Blood Flow Metab 11:A3, 1991.