Renal secretion of xenobiotics mediated by P-glycoprotein: Importance to renal function in health and exploitation for targeted drug delivery to epithelial cysts in polycystic kidney disease

Advanced Drug Delivery Reviews

Volumn 25, Issue 2-3, 1997, Pages 243-256

  Simmons, Nicholas L ^a   Hunter, Janice ^a   Jepson, Mark A ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Cyclosporin A; Digoxin; Drug delivery; P glycoprotein; Renal cysts; Tubular secretion; Vinblastine

Indexed keywords

DISEASES; DRUG PRODUCTS; HEALTH; PHARMACOKINETICS; PHYSIOLOGY; PROTEINS;

CYCLOSPORIN; DIGOXIN; GLYCOPROTEINS; RENAL CYSTS; TUBULAR SECRETION; VINBLASTINE; XENOBIOTICS;

DRUG THERAPY;

CYCLOSPORIN A; DIGOXIN; DOCETAXEL; GLYCOPROTEIN P; VERAPAMIL; VINBLASTINE; XENOBIOTIC AGENT;

ARTICLE; DRUG DELIVERY SYSTEM; HUMAN; KIDNEY CLEARANCE; KIDNEY POLYCYSTIC DISEASE; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE EXCRETION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT;

EID: 0342618583     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(97)00502-4     Document Type: Review

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