Heme from Alzheimer's brain inhibits muscarinic receptor binding via thiyl radical generation

Brain Research

Volumn 764, Issue 1-2, 1997, Pages 93-100

  Venters Jr , Homer D ^a,b,c   Bonilla, Leo E ^a,b,c   Jensen, Tara ^a,b,c   Garner, Hart P ^a,b,c   Bordayo, Elizabeth Z ^a,b,c   Najarian, Melissa M ^a,b,c   Ala, Thomas A ^a,b,c   Mason, Ronald P ^a,b,c   Frey II, William H ^a,b,c  

^a REGIONS HOSPITAL   (United States)

^b University of Minnesota   (United States)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Alzhehner's disease; Antioxidant; Estrogen; Free radical; Heme; Muscarinic receptor; Thiyl radical; Vitamin E

Indexed keywords

ATROPINE; HEMIN; MUSCARINIC RECEPTOR; PEROXIDASE; QUINUCLIDINYL BENZILATE; RADICAL; TRIFLUOROACETIC ACID; TROLOX C;

ALZHEIMER DISEASE; ARTICLE; BLOOD BRAIN BARRIER; CHOLINERGIC NERVE CELL; CHOLINERGIC TRANSMISSION; DRUG RECEPTOR BINDING; ENZYME INHIBITION; HEME SYNTHESIS; HUMAN; MASS SPECTROMETRY; NEUROTOXICITY; OLIVARY NUCLEUS; OXIDATIVE STRESS; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL;

ALZHEIMER DISEASE; ASCORBIC ACID; BRAIN CHEMISTRY; ESTRADIOL; FREE RADICALS; HEME; HUMANS; MASS SPECTROMETRY; MEMBRANES; MUSCARINIC ANTAGONISTS; RECEPTORS, MUSCARINIC; SULFHYDRYL COMPOUNDS; VITAMIN E;

EID: 0342617827     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)00425-3     Document Type: Article

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