Biologically active metabolites from fungi. Part 16: New preussomerins J, K and L from an endophytic fungus: Structure elucidation, crystal structure analysis and determination of absolute configuration by CD calculations

Tetrahedron

Volumn 57, Issue 20, 2001, Pages 4343-4348

  Krohn, Karsten ^a   Flörke, Ulrich ^a   John, Markus ^a   Root, Natalia ^a   Steingröver, Klaus ^a   Aust, Hans Jürgen ^b   Draeger, Siegfried ^b   Schulz, Barbara ^b   Antus, Sándor ^c   Simonyi, Miklos ^d   Zsila, Ferenc ^d  

^a UNIVERSITY OF PADERBORN   (Germany)

^b TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

^c UNIVERSITY OF DEBRECEN   (Hungary)

^d Curriculum Resource Center Budapest   (Hungary)

Author keywords

Antifungal agents; Fungal metabolites; Preussomerins; Spiroketal bisnaphthalenes

Indexed keywords

ANTIINFECTIVE AGENT; BELLADONNA ALKALOID; PREUSSOMERIN DERIVATIVE; PREUSSOMERIN G; PREUSSOMERIN H; PREUSSOMERIN I; PREUSSOMERIN J; PREUSSOMERIN K; PREUSSOMERIN L; UNCLASSIFIED DRUG;

ARTICLE; CALCULATION; CHEMICAL REACTION; CIRCULAR DICHROISM; COMPARATIVE STUDY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG ACTIVITY; DRUG DETERMINATION; DRUG ISOLATION; DRUG STRUCTURE; FUNGUS; MYCELIUM; NONHUMAN; PRIORITY JOURNAL; REACTION ANALYSIS; STRUCTURE ANALYSIS;

EID: 0342468769     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(01)00320-9     Document Type: Article

References (20)

1. Communication No. 15: Krohn, K.; Flörke, U.; Rao, M. S.; Steingröver, K.; Aust, H.-J.; Draeger, S., Schulz, B. Nat. Prod. Lett. 2001, submitted.
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9. Numbering of preussomerins as shown in formula 1 is in accordance with use in Ref. 4.
10. Krohn K., Michel A., Flörke U., Aust H.-J., Draeger S., Schulz B. Liebigs Ann. Chem. 1994;1099-1108.
11. Bringmann G., Busemann S., Krohn K., Beckmann K. Tetrahedron. 53:1997;1655-1664.
12. Krohn K., Beckmann K., Flörke U., Aust H.-J., Draeger S., Schulz B., Busemann S., Bringmann G. Tetrahedron. 53:1997;3101-3110.
13. Krohn K., Beckmann K., Aust H.-J., Draeger S., Schulz B., Busemann S., Bringmann G. Liebigs Annalen/Recueil. 1997;2531-2534.
14. Spartan SGI Version 5.1.3; Wavefunction Inc., Irvine, USA.
15. Browning, J. W. Program package BDZDO/MCDPPD, Department of Chemistry and Biochemistry, University of Colorado, Boulder, USA. Modified by J. Fleischauer, W. Schlecker and B. Kramer, University of Aachen, Germany.
16. Plots of the experimental and calculated spectra of preussomerins G-K are available from the authors via e-mail: kk@chemie.uni-paderborn.de.
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19. Data (excluding structure factors) have been deposited with the Cambridge Crystallographic Data Centre as supplementary publications no. CCDC 148953. Copies of the data can be obtained free of charge on application to CCDC, 12 Union Road, Cambridge CB2 1EZ, UK (fax: +44-(0)1223-336-033; e-mail: deposit@ccdc.cam.ac.uk).
20. SHELXTL NT, Ver. 5.10, Bruker Analytical X-ray Systems, Madison, Wisconsin, USA.