Karyotype of Penicillium nalgiovense and assignment of the penicillin biosynthetic genes to chromosome IV

International Journal of Food Microbiology

Volumn 58, Issue 1-2, 2000, Pages 59-63

  Farber P ^a   Geisen, R ^a  

^a FEDERAL RESEARCH INSTITUTE OF NUTRITION AND FOOD   (Germany)

Author keywords

Fungal starter culture; Karyotype; P. nalgiovense; Penicillin biosynthetic genes

Indexed keywords

PENICILLIN G;

ARTICLE; BIOSYNTHESIS; CHROMOSOME 4; DRUG SYNTHESIS; GENE ASSIGNMENT; GENE CLUSTER; KARYOTYPE; NONHUMAN; PENICILLIUM; PENICILLIUM CHRYSOGENUM; PULSED FIELD GEL ELECTROPHORESIS;

CHROMOSOMES, FUNGAL; DNA, FUNGAL; ELECTROPHORESIS, GEL, PULSED-FIELD; KARYOTYPING; PENICILLINS; PENICILLIUM; PENICILLIUM CHRYSOGENUM;

EID: 0342264581     PISSN: 01681605     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-1605(00)00279-8     Document Type: Article

References (16)

1. Andersen S.J., Frisvad J.C. Penicillin production by Penicillium nalgiovense. Lett. Appl. Microbiol. 19:1994;486-488.
2. Banke S., Frisvad J.C., Rosendahl S. Taxonomy of Penicillium chrysogenum and related xerophilic species based on isozyme analysis. Mycol. Res. 101:1997;617-624.
3. Barredo J.L., Cantoral J.M., Alvarez E., Diez B., Martin J.F. Cloning, sequence analysis and transcriptional study of the isopenicillin N synthase of Penicillium chrysogenum. Mol. Gen. Genet. 216:1989;91-98.
4. Brody H., Carbon J. Electrophoretic karyotype of Aspergillus nidulans. Proc. Natl. Acad. Sci. USA. 86:1989;6260-6263.
5. Färber P. Biosynthese des β-lactam Antibiotikums Penicillin durch den filamentösen Pilz Penicillium nalgiovense, einer Starterkultur zur Herstellung Schimmelpilz-gereifter Fleischwaren. 1999;University of Stuttgart Hohenheim, Germany. Ph.D. Thesis.
6. Färber F., Geisen R. Antagonistic activity of the food relevant filamentous fungus Penicillium nalgiovense is due to the production of penicillin. Appl. Environ. Microbiol. 60:1994;3401-3404.
7. Fierro F., Gutiérrez S., Díez B., Martín J.F. Resolution of four large chromosomes in penicillin-producing filamentous fungi: the penicillin gene cluster is located on chromosome II (9.6 Mb) in Penicillium notatum and chromosome I (10.4 Mb) in Penicillium chrysogenum. Mol. Gen. Genet. 241:1993;573-578.
8. Geisen R. Characterization of the species Penicillium nalgiovense by RAPD and protein patterns and its comparison to Penicillium chrysogenum. Syst. Appl. Microbiol. 18:1996;595-601.
9. Jacobsen T., Hinrichsen L. Bioformation of flavour by Penicillium candidum, Penicillium nalgiovense and Geotrichum candidum on glucose, peptone, maize oil and meat extract. Food Chem. 60:1997;409-416.
10. Kayser T., Schulz G. Electrophoretic karyotype of cellulolytic Penicillium janthinellum strains. Curr. Genet. 20:1991;289-291.
11. Kupfer D.M., Reece C.A., Clifton S.W., Roe B.A., Prade R.A. Multicellular ascomycetous fungal genomes contain more than 8000 genes. Fungal Genet. Biol. 21:1997;364-372.
12. Laich F., Fierro F., Cardoza R.E., Martin J.F. Organization of the gene cluster for biosynthesis of penicillin in Penicillium nalgiovense and antibiotic production in cured dry sausages. Appl. Environ. Microbiol. 65:1999;1236-1240.
13. Maniatis T., Fritsch E.F., Sambrook J. Molecular Cloning. 1989;Cold Spring Harbor Laboratory, Cold Spring Harbour, NY.
14. Samson R.A., van Reenen-Hoekstra E.S. Identification of the common food borne fungi. Samson R.A., van Reenen-Hoekstra E.S. Introduction to Food Borne Fungi. 1988;3-219 Centraalbureau voor Schimmelcultures, Baarn, Netherlands.
15. Schwartz D.C., Saffran W., Welsh J., Haas R., Goldenberg M., Cantor C.R. New techniques for purifying large DNAs and studying their properties and packaging. Cold Spring Habor Symp. Quant. Biol. 47:1983;189-195.
16. Toledo V.M., Selgas M.D., Casas M.C., Ordóñez J.A., García M.L. Effect of selected mould strains on proteolysis in dry fermented sausages. Z. Lebensm. Unters. Forsch. 204:1997;385-390.