Inhibition of Lipase Activities by Citrus Pectin

Journal of Nutritional Science and Vitaminology

Volumn 49, Issue 5, 2003, Pages 340-345

  Tsujita, Takahiro ^a   Sumiyoshi, Maho ^a   Han, Li Kun ^b   Fujiwara, Tsutomu ^c   Tsujita, Junji ^c   Okuda, Hiromichi ^b  

^a EHIME UNIVERSITY   (Japan)

^b PREFECTURAL UNIVERSITY OF KUMAMOTO   (Japan)

^c Research Laboratory   (Japan)

Author keywords

Lingual lipase; Pancreatic lipase; Pectin; Triacylglycerol digestion

Indexed keywords

4 NITROPHENYLBUTYRATE; BUTYRIC ACID DERIVATIVE; CARBOXYLESTERASE; ENZYME ANTIBODY; PANCREATIC LIPASE ANTIBODY; PECTIN; PHOSPHATIDYLCHOLINE; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE; TRIBUTYRIN; TRIOLEIN; UNCLASSIFIED DRUG;

ADSORPTION; ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DETERMINATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; HYDROLYSIS; MALE; MOLECULAR WEIGHT; NONHUMAN; PH; RAT; TRIACYLGLYCEROL BLOOD LEVEL; WESTERN BLOTTING;

ANIMALIA; CITRUS; GLYCINE MAX;

EID: 0242660540     PISSN: 03014800     EISSN: 18817742     Source Type: Journal    
DOI: 10.3177/jnsv.49.340     Document Type: Article

References (26)

1. Hexeberg S, Hexeberg E, Willumsen N, Berge PK. 1994. A study on lipid metabolism in heart and liver of cholesterol- and pectin-fed rats. Br J Nutr 71: 181-192.
2. Tinker LF, Davis PA, Schneeman BO. 1994. Prune fiber or pectin compared with cellulose lowers plasma and liver lipids in rats with diet-induced hyperlipidemia. J Nutr 124: 31-40.
3. Anderson JW, Jones AE, Riddell-Mason S. 1994. Ten different dietary fibers have significantly different effects on serum and liver lipids of cholesterol-fed rats. J Nutr 124: 78-83.
4. Shen H, He L, Price RL, Fernandez ML. 1998. Dietary soluble fiber lowers plasma LDL cholesterol concentrations by altering lipoprotein metabolism in female guinea pigs. J Nutr 128: 1434-1441.
5. Brown L, Rosner B, Willett WW, Sacks FM. 1999. Cholesterol-lowering effects of dietary fiber: a meta-analysis. Am J Clin Nutr 69: 30-42.
6. Hamosh M, Klaevman HL, Wolf RO, Scow RO. 1975. Pharyngeal lipase and digestion of dietary triglyceride in man. J Clin Invest 55: 908-913.
7. Redd ER, Brockman HL. 1984. Pancreatic carboxylester lipase. In: Lipases (Borgström B, Brockman HL, eds). p 185-204. Elsevier, Amsterdam.
8. Rietsch J, Pattus F, Desnuelle P, Verger R. 1977. Further studies of mode of action of lipolytic enzymes. J Biol Chem 252: 4313-4318.
9. Hansen WE. 1987. Effect of dietary fiber on pancreatic lipase activity in vitro. Pancreas 2: 195-198.
10. Hendrick JA, Tadokoro T, Emenhiser C, Nienaber U, Fennema OR. 1992. Various dietary fibers have different effects on lipase-catalyzed hydrolysis of tributyrin in vitro. J Nutr 122: 269-277.
11. Tsujita T, Miyazaki T, Tabi R, Okuda H. 1996. Coenzyme A-independent monoacylglycerol acyltransferase from rat intestinal mucosa. J Biol Chem 271: 2156-2161.
12. Tsujita T, Okuda H. 1990. Effect of bile salts on the interfacial inactivation of pancreatic carboxylester lipase. J Lpid Res 31: 831-838.
13. Nakagawa A, Tsujita T, Okuda H. 1984. Effect of Briji 58 on the hydrolysis of methylbutyrate by lipase from Pseudomonas fluorescens. J Biochem 96: 815-820.
14. Tsujita T, Matsuura Y, Okuda H. 1996. Studies on the inhibition of pancreatic and carboxylester lipase by protamine. J Lipid Res 37: 1481-1487.
15. Tsujita T, Nakagawa A, Shirai K, Saito Y, Okuda H. 1984. Methyl butyrate-hydrolyzing activity of hepatic triglyceride lipase from rat post heparin plasma. J Biol Chem 25: 11215-11220.
16. Morimoto C, Kiyama A, Kameda K, Ninmiya H, Tsujita T, Okuda H. 2000. Mechanism of the stimulatory action of okadaic acid on lipolysis in rat fat cells. J Lipid Res 41: 199-204.
17. Rietsch J, Pattus F, Desnuelle P, Verger R. 1977. Further studies of mode of action of lipolytic enzymes. J Biol Chem 252: 4313-4318.
18. Gargouri Y, Julien R, Sugihara A, Verger R, Sarda L. 1984. Inhibition on pancreatic and microbial lipase by proteins. Biochim Biophys Acta 795: 326-331.
19. Ferreira GC, Patton JS. 1990. Inhibition of lipolysis by hydrocarbons and fatty alcohols. J Lipid Res 31: 889-897.
20. Bae JH, Bassenge E, Kim KB, Kim YM, Kim KS, Lee HJ, Moon KC, Lee MS, Park KY, Schwemmer M. 2001. Postprandial hypertriglyceridemia impairs endothelial function by enhanced oxidant stress. Atherosclerosis 155: 517-523.
21. Bae JH, Bassenge E, Kim KB, Lee HJ, Park KR, Park CG, Park KY, Lee MS, Schwemmer M. 2001. Impact of postprandial hypertriglyceridemia on vascular responses in patients with coronary artery disease: effects of ACE inhibitors and fibrates. Atherosclerosis 158: 165-171.
22. Kimura W, Mossner J. 1996. Role of hypertriglyceridemia in the pathogenesis of experimental acute pancreatitis in rats. Int J Pancreatol 20: 177-184.
23. Tosles PP. 1990. Hyperlipidemic pancreatitis. Gastroenterol Clin North Am 19: 783-791.
24. Isaksson G, Lundquist I, Ihse I. 1982. Effect of dietary fiber on pancreatic enzyme activity in vitro. Gastroenterology 82: 918-924.
25. Mokady S. 1973. Effect of dietary pectin and algin on blood cholesterol level in growing rats fed a cholesterol-free diet. Nutri Metab 15: 290-294.
26. Yamaguchi F, Uchida S, Watabe S, Kojima H, Shimizu N, Hatanaka C. 1995. Relationship between molecular weights of pectin and hypocholesterolemic effects in rats. Biosci Biotechnol Biochem 59: 2130-2131.