Hrs function: Viruses provide the clue

Trends in Cell Biology

Volumn 13, Issue 12, 2003, Pages 603-606

  Clague, Michael J ^a   Urbé, Sylvie ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN; PROTEIN HRS; TUMOR SUSCEPTIBILITY GENE 101 PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN;

CELL MEMBRANE; ENDOSOME; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN TRANSPORT; RECEPTOR DOWN REGULATION; REVIEW; RNA VIRUS;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0242643727     PISSN: 09628924     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tcb.2003.10.002     Document Type: Short Survey

References (28)

1. Piper R.C., Luzio J.P. Late endosomes: sorting and partitioning in multivesicular bodies. Traffic. 2:2001;612-621.
2. Raymond C.K., et al. Morphological classification of the yeast vacuolar protein sorting mutants: evidence for a prevacuolar compartment in class E vps mutants. Mol. Biol. Cell. 3:1992;1389-1402.
3. Katzmann D.J., et al. Receptor downregulation and multivesicular-body sorting. Nat. Rev. Mol. Cell Biol. 3:2002;893-905.
4. Pornillos O., et al. Mechanisms of enveloped RNA virus budding. Trends Cell Biol. 12:2002;569-579.
5. Freed E.O. Viral late domains. J. Virol. 76:2002;4679-4687.
6. Garrus J.E., et al. Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding. Cell. 107:2001;55-65.
7. Katzmann D.J., et al. Vps27 recruits ESCRT machinery to endosomes during MVB sorting. J. Cell Biol. 162:2003;413-423.
8. Lu Q., et al. TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation. Proc. Natl. Acad. Sci. U. S. A. 100:2003;7626-7631.
9. Bache K.G., et al. Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes. J. Cell Biol. 162:2003;435-442.
10. Pornillos O., et al. HIV Gag mimics the Tsg101-recruiting activity of the human Hrs protein. J. Cell Biol. 162:2003;425-434.
11. Tanzi G.O., et al. Equine infectious anemia virus utilizes host vesicular protein sorting machinery during particle release. J. Virol. 77:2003;8440-8447.
12. Raposo G., et al. Human macrophages accumulate HIV-1 particles in MHC II compartments. Traffic. 3:2002;718-729.
13. Pelchen-Matthews A., et al. Infectious HIV-1 assembles in late endosomes in primary macrophages. J. Cell Biol. 162:2003;443-455.
14. Stoorvogel W., et al. The biogenesis and functions of exosomes. Traffic. 3:2002;321-330.
15. Urbé S., et al. Endosomal localization and receptor dynamics determine tyrosine phosphorylation of hepatocyte growth factor-regulated tyrosine kinase substrate. Mol. Cell. Biol. 20:2000;7685-7692.
16. Gillooly D.J., et al. Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells. EMBO J. 19:2000;4577-4588.
17. Raiborg C., et al. Hrs recruits clathrin to early endosomes. EMBO J. 20:2001;5008-5021.
18. Sachse M., et al. Bilayered clathrin coats on endosomal vacuoles are involved in protein sorting toward lysosomes. Mol. Biol. Cell. 13:2002;1313-1328.
19. Raiborg C., et al. Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes. Nat. Cell Biol. 4:2002;394-398.
20. Urbé S., et al. The UIM domain of Hrs couples receptor sorting to vesicle formation. J. Cell Sci. 116:2003;4169-4179.
21. Kato M., et al. A de-ubiquitinating enzyme UBPY interacts with the SH3 domain of Hrs binding protein via a novel binding motif Px(V/I)(D/N)RxxKP. J. Biol. Chem. 275:2000;37481-37487.
22. Goila-Gaur R., et al. Defects in human immunodeficiency virus budding and endosomal sorting induced by TSG101 overexpression. J. Virol. 77:2003;6507-6519.
23. Tsujimoto S., Bean A.J. Distinct protein domains are responsible for the interaction of Hrs-2 with SNAP-25. J. Biol. Chem. 275:2000;2938-2942.
24. Kwong J., et al. Hrs interacts with SNAP-25 and regulates Ca(2+)-dependent exocytosis. J. Cell Sci. 113:2000;2273-2284.
25. Sollner T., et al. SNAP receptors implicated in vesicle targeting and fusion. Nature. 362:1993;318-324.
26. Bean A.J., et al. Hrs-2 is an ATPase implicated in calcium-regulated secretion. Nature. 385:1997;826-829.
27. Raiborg C., et al. FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes. J. Cell Sci. 114:2001;2255-2263.
28. Sun W., et al. Hrs regulates early endosome fusion by inhibiting formation of an endosomal SNARE complex. J. Cell Biol. 162:2003;125-137.