Guanine nucleotide-sensitive inhibition of L-type Ca2+ current by lysosphingolipids in RINm5F insulinoma cells

Molecular Pharmacology

Volumn 53, Issue 5, 1998, Pages 862-869

  Himmel, Herbert M ^a,b   Meyer Zu Heringdorf, Dagmar ^a   Windorfer, Bernd ^a   Van Koppen, Chris J ^a   Ravens, Ursula ^a,b   Jakobs, Karl H ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; CLONIDINE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE; GUANOSINE 5' O (2 THIODIPHOSPHATE); MEMBRANE RECEPTOR; PSYCHOSINE; SPHINGOLIPID; SPHINGOSINE 1 PHOSPHATE;

ARTICLE; CALCIUM CURRENT; CALCIUM HOMEOSTASIS; DEPOLARIZATION; ELECTROPHYSIOLOGY; HUMAN; HUMAN CELL; INSULINOMA; MEMBRANE POTENTIAL; PRIORITY JOURNAL;

BARIUM; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CALCIUM CHANNELS, L-TYPE; CELL LINE; GUANINE NUCLEOTIDES; HUMANS; INSULINOMA; LYSOPHOSPHOLIPIDS; PHOSPHORYLCHOLINE; POTASSIUM CHLORIDE; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, ADRENERGIC, BETA; RECEPTORS, ADRENERGIC, BETA-3; SPHINGOSINE; TUMOR CELLS, CULTURED;

EID: 2642642959     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Ashcroft FM and Rorsman P (1989) Electrophysiology of the pancreatic β-cell. Prog Biophys Mol Biol 54:87-143.
2. Bennett DL, Cheek TR, Berridge MJ, De Smedt H, Parys JB, Missiaen L, and Bootman MD (1996) Expression and function of ryanodine receptors in nonexcitable cells. J Biol Chem 271:6356-6362.
3. Birnbaumer L, Campbell KP, Catterall WA, Harpold MM, Hofmann F, Home WA, Mori Y, Schwartz A, Snutch TP, Tanabe T, and Tsien RW (1994) The naming of voltage-gated calcium channels. Neuron 13:505-506.
4. Bünemann M, Liliom K, Brandts B, Pott L, Tseng JL, Desiderio DM, Sun G, Miller D, and Tigyi G (1996) A novel membrane receptor with high affinity for lysosphingomyelin and sphingosine-1-phosphate in atrial myocytes. EMBO J 15:5527-5534.
5. Choi OH, Kim J, and Kinet J (1996) Calcium mobilization via sphingosine kinase in signalling by the FcεRI antigen receptor. Nature (Lond) 380:634-636.
6. de Waard M, Gurnett CA, and Campbell KP (1996) Structural and functional diversity of voltage-activated calcium channels. Ion Channels 4:41-87.
7. 2+ currents in insulin-secreting cells. FEBS Lett 189:281-285.
8. Ghosh TK, Bian J, and Gill DL (1994) Sphingosine-1-phosphate generated in the endoplasmic reticulum membrane activates release of stored calcium. J Biol Chem 269:22628-22635.
9. Hannun YA and Bell RM (1987) Lysosphingolipids inhibit protein kinase C: Implications for the sphingolipidoses. Science (Washington DC) 235:670-674.
10. Ji S, Weiss JA and Langer GA (1993) Modulation of voltage-dependent sodium and potassium currents by charged amphiphiles in cardiac ventricular myocytes: effects via modification of surface potential. J Gen Physiol 101:355-375.
11. 1-subunit. Am J Physiol 272:H1372-H1381.
12. Martinac B, Adler J, and Kung C (1990) Mechanosensitive ion channels of E. coli activated by amphipaths. Nature (Lond) 348:261-263.
13. Mattie ME, Brooker G, and Spiegel S (1996) Sphingosine-1-phosphate, a putative second messenger, mobilizes calcium from internal stores via an inositol trisphosphate-independent pathway. J Biol Chem 269:3181-3188.
14. 2+ channel conductance. Circ Res 75:981-989.
15. Meyer zu Heringdorf D, van Koppen CJ, and Jakobs KH (1997) Molecular diversity of sphingolipid signalling. FEBS Lett 410:34-38.
16. Meyer zu Heringdorf D, van Koppen CJ, Windorfer B, Himmel HM, and Jakobs KH (1996) Calcium signalling by G-protein-coupled sphingolipid receptors in bovine aortic endothelial cells. Naunyn-Schmiedebergs Arch Pharmacol 354:1-7.
17. 2+ mobilization by sphingosylphosphorylcholine and galactosylsphingosine in HL60 leukemia cells: implications of GTP-binding protein-coupled receptors for lysosphingolipids. J Biol Chem 270:26332-26340.
18. Olivera A and Spiegel S (1993) Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens. Nature (Lond) 365:557-560.
19. 1 subunit is responsible for channel inhibition by G protein-coupled receptors. Proc Natl Acad Sci USA 94:8866-8871.
20. 2+-currents in an insulin-secreting cell line (RINm5F). J Biol Chem 266:18025-18033.
21. Sharp GWG (1997) Mechanisms of inhibition of insulin release. Am J Physiol 271:C1781-C1799.
22. Spiegel S, Foster D, and Kolesnick R (1996) Signal transduction through lipid second messengers. Curr Opin Cell Biol 8:159-167.
23. 1 cells, Endocrinology 136:4894-4902.
24. i protein-coupled plasma membrane receptor by sphingosine-1-phosphate. J Biol Chem 271:2082-2087.
25. i protein-coupled receptor for sphingosylphosphorylcholine in human leukemia HL-60 cells and human neutrophils. Mol Pharmacol 49:956-961.
26. Wickman KD and Clapham DE (1995) G-protein regulation of ion channels. Curr Opin Neurobiol 5:278-285.
27. Yasui K and Palade P (1996) Sphingolipid actions on sodium and calcium currents of rat ventricular myocytes. Am J Physiol 270:C645-C649.