Calphostin C as a rapid and strong inducer of apoptosis in human coronary artery smooth muscle cells

International Immunopharmacology

Volumn 3, Issue 13-14, 2003, Pages 1751-1759

  Krueger, Kristopher D ^a   Hunter III, William J ^a   DelCore, Michael G ^a   Agrawal, Devendra K ^a  

^a CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Calphostin C; Insulin like growth factor I; Time lapse videomicroscopy; Vascular smooth muscle

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CALPHOSTIN C; PROTEIN KINASE C INHIBITOR; SOMATOMEDIN C; STAUROSPORINE; WORTMANNIN;

APOPTOSIS; ARTERY MUSCLE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HUMAN TISSUE; NICK END LABELING; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; SCANNING ELECTRON MICROSCOPY; SIGNAL TRANSDUCTION;

EID: 0242628283     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1567-5769(03)00206-6     Document Type: Article

References (32)

1. Breslow J.L. Cardiovascular disease burden increases. NIH funding decreases. Nat. Med. 3(6):1997;600-601.
2. Braunwald E. Shattuck lecture-cardiovascular medicine at the turn of the millennium: triumph, concerns, and opportunities. N. Engl. J. Med. 337(19):1997;1360-1369.
3. Cowley M.J., Vetrovec G.W., Wolfgang T.C. Efficacy of percutaneous transluminal coronary angioplasty: technique, patient selection, salutary results, limitations and complications. Am. Heart J. 101(3):1981;272-280.
4. Dichek D.A., Neville R.F., Zwiebel J.A., Freeman S.M., Leon M.B., et al. Seeding of intravascular stents with genetically engineered endothelial cells. Circulation. 80(5):1989;1347-1353.
5. Dangas G., Fuster V. Management of restenosis after coronary intervention. Am. Heart J. 132(2 Pt 1):1996;428-436.
6. Allen R.T., Cluck M.W., Agrawal D.K. Mechanisms controlling cellular suicide: role of Bcl-2 and caspases. Cell. Mol. Life Sci. 54:1998;427-445.
7. Slomp J., Gittenberger-de Groot A.C., Glukhova M.A., Conny van Munsteren J., Kockx M.M., et al. Differentiation, dedifferentiation, and apoptosis of smooth muscle cells during the development of the human ductus arteriosus. Arterioscler. Thromb. Vasc. Biol. 17(5):1997;1003-1009.
8. Isner J.M., Kearney M., Bortman S., Passeri J. Apoptosis in human atherosclerosis and restenosis. Circulation. 91(11):1995;2703-2711.
9. Bauriedel G., Schluckebier S., Hutter R., Welsch U., Kandolf R., et al. Apoptosis in restenosis versus stable-angina atherosclerosis: implications for the pathogenesis of restenosis. Arterioscler. Thromb. Vasc. Biol. 18(7):1998;1132-1139.
10. Bennett M.R., Evan G.I., Schwartz S.M. Apoptosis of human vascular smooth muscle cells derived from normal vessels and coronary atherosclerotic plaques. J. Clin. Invest. 95(5):1995;2266-2274.
11. Allen T., Krueger K., Murphy L., Agrawal D.K. Insulin-like growth factor-I mediated survival and stress kinase inhibition signals diverge downstream of phosphatidylinositol 3-kinase in vascular smooth muscle cells [abstract]. Circulation. 100:1999;I283.
12. Kobayashi E., Nakano H., Morimoto M., Tamaoki T. Calphostin C [UCN-1028C], a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C. Biochem. Biophys. Res. Commun. 159(2):1989;548-553.
13. Knedler A., Ham R.G. Optimized medium for clonal growth of human microvascular endothelial cells with minimal serum. In Vitro Cell. Dev. Biol. 23(7):1987;481-491.
14. Toker A. Signaling though protein kinase C. Front. Biosci. 3:1998;1134-1147.
15. Gubina E., Rinaudo M.S., Szallasi Z., Blumberg P.M., Mufson R.A. Overexpression of protein kinase C isoform ε but not δ in human interleukin-3-dependent cells suppresses apoptosis and induces bcl-2 expression. Blood. 91:1998;823-829.
16. Nishizuka Y. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science. 258:1992;607-614.
17. Mellor H., Parker P. The extended protein kinase C superfamily. Biochem. J. 332:1998;281-292.
18. Gordge P.C., Ryves W.J. Inhibitors of protein kinase C. Cell. Signal. 6:1994;871-882.
19. Shen G.X., Way K.J., Jacobs J.R., King G.L. Applications of inhibitors for protein kinase C and their isoforms. Methods Mol. Biol. 233:2003;397-422.
20. Dubauskas Z., Beck T.P., Chmura S.J., Kovar D.A., Kadkhodaian M.M., et al. Activated calphostin C cytotoxicity is independent of p53 status and in vivo metastatic potential. Clin. Cancer Res. 4(10):1998;2391-2398.
21. Leszczynski D., Zhao Y., Luokkamaki M., Foegh M.L. Apoptosis of vascular smooth muscle cells. Protein kinase C and oncoprotein Bcl-2 are involved in regulation of apoptosis in non-transformed rat vascular smooth muscle cells. Am. J. Pathol. 145(6):1994;1265-1270.
22. Ibe W., Bartels W., Lindemann S., Grosser T., Buerke M., et al. Involvement of PKC and NF-kappaB in nitric oxide induced apoptosis in human coronary artery smooth muscle cells. Cell. Physiol. Biochem. 11(5):2001;231-240.
23. Champagne M.J., Dumas P., Orlov S.N., Bennett M.R., Hamet P., et al. Protection against necrosis but not apoptosis by heat-stress proteins in vascular smooth muscle cells: evidence for distinct modes of cell death. Hypertension. 33(3):1999;906-913.
24. Allen R.T., Pai J., Bovard K., Hunter W.J. III, Agrawal D.K. Immunogold staining for Bcl-xL and morphological analysis of rat and human vascular smooth muscle cells undergoing apoptosis induced by c-myc or staurosporine. Scanning. 20(3):1998;207-208.
25. Nishio E., Watanabe Y. Nitric oxide donor-induced apoptosis in smooth muscle cells is modulated by protein kinase C and protein kinase A. Eur. J. Pharmacol. 339(2-3):1997;245-251.
26. Li P.F., Maasch C., Haller H., Dietz R., von Harsdorf R. Requirement for protein kinase C in reactive oxygen species-induced apoptosis of vascular smooth muscle cells. Circulation. 100(9):1999;967-973.
27. Darzynkiewicz Z., Juan G., Li X., Gorczyca W., Murakami T., et al. Cytometry in cell necrobiology: analysis of apoptosis and accidental cell death [necrosis]. Cytometry. 27(1):1997;1-20.
28. Berridge M.V., Tan A.S. Interleukin-3 facilitates glucose transport in a myeloid cell line by regulating the affinity of the glucose transporter for glucose: involvement of protein phosphorylation in transporter activation. Biochem. J. 305:1995;843-851.
29. Bai H., Pollman M.J., Inishi Y., Gibbons G.H. Regulation of vascular smooth muscle cell apoptosis. Modulation of bad by a phosphatidylinositol 3-kinase-dependent pathway. Circ. Res. 85(3):1999;229-237.
30. Treisman R. Regulation of transcription by MAP kinase cascades. Curr. Opin. Cell Biol. 8(2):1996;205-215.
31. Perlman H., Maillard L., Krasinski K., Walsh K. Evidence for the rapid onset of apoptosis in medial smooth muscle cells after balloon injury. Circulation. 95(4):1997;981-987.
32. Pollman M.J., Hall J.L., Gibbons G.H. Determinants of vascular smooth muscle cell apoptosis after balloon angioplasty injury. Influence of redox state and cell phenotype. Circ. Res. 84(1):1999;113-121.