The value of perinatal immune responses in predicting allergic disease at 6 years of age

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 58, Issue 11, 2003, Pages 1187-1194

  Prescott, S L ^a   King, B ^a   Strong, T L ^a   Holt, P G ^b  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Allergens; Allergy; Cord blood; Cytokines; Infants

Indexed keywords

ALLERGEN; CYTOKINE; GAMMA INTERFERON; HOUSE DUST ALLERGEN; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; MESSENGER RNA; OVALBUMIN; PHYTOHEMAGGLUTININ; TETANUS TOXOID;

ALLERGIC DISEASE; ALLERGIC RHINITIS; ARTICLE; ASTHMA; ATOPIC DERMATITIS; ATOPY; CHILDHOOD DISEASE; COHORT ANALYSIS; CONTROLLED STUDY; ECZEMA; FAMILY HISTORY; FOLLOW UP; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LYMPHOCYTE PROLIFERATION; MAJOR CLINICAL STUDY; MONONUCLEAR CELL; NEWBORN; PERINATAL PERIOD; PREDICTION; PRESCHOOL CHILD; PRICK TEST; PRIORITY JOURNAL; REGRESSION ANALYSIS; TH1 CELL; UMBILICAL CORD BLOOD;

ALLERGENS; CHILD; CHILD, PRESCHOOL; CYTOKINES; FETAL BLOOD; FOLLOW-UP STUDIES; HUMANS; HYPERSENSITIVITY; IMMUNOLOGIC TESTS; INFANT, NEWBORN; INTERFERON TYPE II; LYMPHOCYTE ACTIVATION; PHYTOHEMAGGLUTININS; PREDICTIVE VALUE OF TESTS; RISK FACTORS; SKIN TESTS;

EID: 0242624687     PISSN: 01054538     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1398-9995.2003.00263.x     Document Type: Article

References (20)

1. HOLT P. Post-natal maturation of immune competence in infancy and childhood. Pediatr Allergy Immunol 1995;6:59-70.
2. PRESCOTT S, MACAUBAS C, SMALLACOMBE T, HOLT B, SLY P, LOH R et al. Development of allergen-specific T-cell memory in atopic and normal children. Lancet 1999;353:196-200.
3. KONDO N, KOBAYASHI Y, SHINODA S, KASAHARA K, KAMEYAMA T, IWASA S et al. Cord blood lymphocyte responses to food antigens for the prediction of allergic disorders. Arch Dis Child 1992;67:1003-1007.
4. WARNER JA, MILES EA, JONES AC, QUINT DJ, COLWELL BM, WARNER JO. Is deficiency of interferon gamma production by allergen triggered cord blood cells a predictor of atopic eczema? Clin Exp Allergy 1994;24:423-430.
5. TANG MLK, KEMP AS, THORBURN J, HILL D. Reduced interferon gamma secretion in neonates and subsequent atopy. Lancet 1994;344:983-985.
6. MARTINEZ F, STERN D, WRIGHT A, HOLBERG C, TAUSSIG L, HALONEN M. Association of interleukin-2 and interferon-γ production by blood mononuclear cells in infancy with parental allergy skin tests and with subsequent development of atopy. J Allergy Clin Immunol 1995;96:652-660.
7. LIAO S, LIAO T, CHIANG B, HUANG M, CHEN C, CHOU C et al. Decreased production of IFN-γ and decreased production of IL-6 by cord blood mononuclear cells of newborns with a high risk of allergy. Clin Exp Allergy 1996;26:397-405.
8. KONDO N, KOBAYASHI Y, SHINODA S, TAKENAKA R, TERAMOTO T, KANEKO H et al. Reduced interferon gamma production by antigen-stimulated cord blood mononuclear cells is a risk factor of allergic disorders - 6-year follow-up study. Clin Exp Allergy 1998;28:1340-1344.
9. MACAUBAS C, SLY PD, BURTON P, TILLER K, YABUHARA A, HOLT BJ et al. Regulation of Th-cell responses to inhalant allergen during early childhood. Clin Exp Allergy 1999;29:1223-1231.
10. PRESCOTT S, MACAUBAS C, HOLT B, SMALLACOMBE T, LOH R, SLY P et al. Transplacental priming of the human immune system to environmental allergens: universal skewing of initial T-cell responses towards Th-2 cytokine profile. J Immunol 1998;160:4730-4737.
11. STEINBORN A, GUNES H, HALBERSTADT E. Signal for term parturition if of trophoblast and therefore fetal origin. Prostaglandins 1995;50:237-252.
12. JOHANSSON SG, HOURIHANE JO, BOUSQUET J, BRUIJNZEEL-KOOMEN C. DREBORG S, HAAHTELA T et al. A revised nomenclature for allergy. An EAACI position statement from the EAACI nomenclature task force. Allergy 2001;56:813-824.
13. HANIFEN J, RAJKA G. Diagnostic features of atopic dermatitis. Acta Derm Venereol (Stockh) 1980; 92(Suppl. 144):44-47.
14. DREBORG S. The skin prick test: methodological studies and clinical applications. Linköping University Medical Dissertations. Linköping: VTT-Grafiska Vimmerby, 1987.
15. PRESCOTT SL, MACAUBAS C, SMALLACOMBE T, HOLT BJ, SLY PD, LOH R et al. Reciprocal age-related patterns of allergen-specific T-cell immunity in normal vs. atopic infants. Clin Exp Allergy 1998;28(Suppl. 5):39-44; discussion 50-51.
16. UPHAM JW, HOLT BJ, BARON-HAY MJ, YABUHARA A, HALES BJ, THOMAS WR et al. Inhalant allergen-specific T-cell reactivity is detectable in close to 100% of atopic and normal individuals: covert responses are unmasked by serum-free medium. Clin Exp Allergy 1995;25:634-642.
17. NG TW, HOLT PG, PRESCOTT SL. Cellular immune responses to ovalbumin and house dust mite in egg-allergic children. Allergy 2002;57:207-214.
18. HOLT PG, RUDIN A, MACAUBAS C, HOLT BJ, ROWE J, LOH R et al. Development of immunologic memory against tetanus toxoid and pertactin antigens from the diphtheria-tetanus-pertussis vaccine in atopic versus nonatopic children. J Allergy Clin Immunol 2000;105:1117-1122.
19. WILLIAMS TJ, JONES CA, MILES EA, WARNER JO, WARNER JA. Fetal and neonatal IL-13 production during pregnancy and at birth and subsequent development of atopic symptoms. J Allergy Clin Immunol 2000;105:951-959.
20. GABRIELSSON S, SODERLUND A, NILSSON C, LILJA G, NORDLUND M, TROYEBLOMBERG M. Influence of atopic heredity on IL-4-, IL-12- and IFN-gamma-producing cells in in vitro activated cord blood mononuclear cells. Clin Exp Immunol 2001;126:390-396.