In vitro/in vivo evaluation of the efficiency of teicoplanin-loaded biodegradable microparticles formulated for implantation to infected bone defects

Journal of Microencapsulation

Volumn 20, Issue 6, 2003, Pages 705-717

  Yenice, I ^a   Calis S ^a   Atilla, B ^b   Kas H S ^a   Ozalp M ^a   Ekizoglu M ^a   Bilgili, H ^c   Hincal, A A ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

^b Faculty of Medicine   (Turkey)

^c ANKARA UNIVERSITY   (Turkey)

Author keywords

Implant; Microbiological assay; Osteomyelitis; PLGA microspheres; Teicoplanin

Indexed keywords

MICROSPHERE; POLYGLACTIN; POLYMER; POLYPEPTIDE ANTIBIOTIC AGENT; TEICOPLANIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMICROBIAL ACTIVITY; ARTICLE; BIODEGRADABLE IMPLANT; BONE DEFECT; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; DRUG FORMULATION; DRUG STABILITY; DRUG SYNOVIAL FLUID LEVEL; FEMUR CONDYLE; GRAM POSITIVE BACTERIUM; IN VITRO STUDY; IN VIVO STUDY; LOADING TEST; MICROBIOLOGY; NONHUMAN; OSTEOMYELITIS; PARTICLE SIZE; SURFACE PROPERTY; SUSTAINED DRUG RELEASE;

ANIMALS; ANTI-BACTERIAL AGENTS; BIOCOMPATIBLE MATERIALS; BIODEGRADATION, ENVIRONMENTAL; BONE DISEASES, INFECTIOUS; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG COMPOUNDING; LACTIC ACID; MICROBIAL SENSITIVITY TESTS; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; OSTEOMYELITIS; PARTICLE SIZE; POLYGLYCOLIC ACID; POLYMERS; RABBITS; STAPHYLOCOCCAL INFECTIONS; SYNOVIAL FLUID; TEICOPLANIN; TIME FACTORS;

EID: 0242610371     PISSN: 02652048     EISSN: None     Source Type: Journal    
DOI: 10.1080/0265204031000154179     Document Type: Article

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