Insulin-like growth factor binding protein-2 modulates podocyte mitogenesis

Pediatric Nephrology

Volumn 18, Issue 11, 2003, Pages 1109-1115

  Bridgewater, Darren J ^a   Matsell, Douglas G ^b  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b CHILDREN S HOSPITAL OF WESTERN ONTARIO   (Canada)

Author keywords

Cell mitogenesis; Human kidney; IGF binding proteins; Insulin like growth factors; Podocyte (glomerular epithelial cell); Renal disease

Indexed keywords

ALPHA ACTIN; COMPLEMENT RECEPTOR; CYTOSKELETON PROTEIN; MESSENGER RNA; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN 2; TUMOR SUPPRESSOR PROTEIN; VIMENTIN;

ARTICLE; AUTOCRINE EFFECT; CELL DIFFERENTIATION; CELL ISOLATION; CELL LINEAGE; CELL MATURATION; CELL STIMULATION; CELL STRUCTURE; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; EPITHELIUM CELL; FETUS; FETUS CELL; GESTATION PERIOD; GLOMERULUS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREACTIVITY; INCUBATION TIME; KIDNEY DEVELOPMENT; MESSENGER RNA SYNTHESIS; MITOGENESIS; MONOLAYER CULTURE; NEPHROBLASTOMA; PODOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING;

CELL SEPARATION; CELLS, CULTURED; EPITHELIAL CELLS; FETUS; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 2; INSULIN-LIKE GROWTH FACTOR II; KIDNEY GLOMERULUS; MITOSIS; RECOMBINANT PROTEINS;

EID: 0242610295     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00467-003-1242-x     Document Type: Article

References (37)

1. Mundel P, Reiser J (1997) New aspects of podocyte cell biology. Kidney Blood Press Res 20:173-176
2. Putaala H, Soininen R, Kilpelainen P, Wartiovaara J, Tryggvason K (2001) The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death. Hum Mol Genet 10:1-8
3. Boute N, Gribouval O, Roselli S, Benessy F, Lee H, Fuchshuber A, Dahan K, Gubler MC, Niaudet P, Antignac C (2000) NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome. Nat Genet 24:349-354
4. Kaplan JM, Kim SH, North KN, Rennke H, Correia LA, Tong HQ, Mathis BJ, Rodriguez-Perez JC, Allen PG, Beggs AH, Pollak MR (2000) Mutations in ACTN4, encoding alpha-actin-in-4, cause familial focal segmental glomerulosclerosis. Nat Genet 24:251-256
5. Shih NY, Li J, Karpitskii V, Nguyen A, Dustin ML, Kanagawa O, Miner JH, Shaw AS (1999) Congenital nephrotic syndrome in mice lacking CD2-associated protein. Science 286:312-315
6. Matsell DG, Delhanty PJ, Stepaniuk O, Goodyear C, Han VK (1994) Expression of insulin-like growth factor and binding protein genes during nephrogenesis. Kidney Int 46:1031-1042
7. Matsell DG, Gaber LW, Malik KU (1994) Cytokine stimulation of prostaglandin production inhibits the proliferation of serum-stimulated mesangial cells. Kidney Int 45:159-165
8. Mundel P, Reiser J, Kriz W (1997) Induction of differentiation in cultured rat and human podocytes. J Am Soc Nephrol 8: 697-705
9. Matsell DG, Gaber LW, Sehic E, Malik KU (1993) Interleukin 1 and interleukin 6 inhibition of mesangial cell proliferation: role of PGE2. J Lipid Mediat 6:343-352
10. Matsell DG, Bennett T (1998) Evaluation of metanephric maturation in a human fetal kidney explant model. In Vitro Cell Dev Biol Anim 34:138-148
11. Lipschutz JH (1998) Molecular development of the kidney: a review of the results of gene disruption studies. Am J Kidney Dis 31:383-397
12. Bates CM (2000) Kidney development: regulatory molecules crucial to both mice and men. Mol Genet Metab 71:391-396
13. Sariola H, Saarma M (1999) GDNF and its receptors in the regulation of the ureteric branching. Int J Dev Biol 43: 413-418
14. Schuchardt A, D'Agati V, Larsson-Blomberg L, Costantini F, Pachnis V (1994) Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret. Nature 367:380-383
15. Pichel JG, Shen L, Sheng HZ, Granholm AC, Drago J, Grinberg A, Lee EJ, Huang SP, Saarma M, Hoffer BJ, Sariola H, Westphal H (1996) Defects in enteric innervation and kidney development in mice lacking GDNF. Nature 382:73-76
16. Jena N, Martin-Seisdedos C, McCue P, Croce CM (1997) BMP7 null mutation in mice: developmental defects in skeleton, kidney, and eye. Exp Cell Res 230:28-37
17. Rogers SA, Ryan G, Hammerman MR (1992) Metanephric transforming growth factor-alpha is required for renal organogenesis in vitro. Am J Physiol 262:F533-F539
18. Threadgill DW, Dlugosz AA, Hansen LA, Tennenbaum T, Lichti U, Yee D, LaMantia C, Mourton T, Herrup K, Harris RC (1995) Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype. Science 269:230-234
19. Rogers SA, Ryan G, Hammerman MR (1991) Insulin-like growth factors I and II are produced in the metanephros and are required for growth and development in vitro. J Cell Biol 113:1447-1453
20. Baker J, Liu JP, Robertson EJ, Efstratiadis A (1993) Role of insulin-like growth factors in embryonic and postnatal growth. Cell 75:73-82
21. DeChiara TM, Efstratiadis A, Robertson EJ (1990) A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting. Nature 345:78-80
22. Liu JP, Baker J, Perkins AS, Robertson EJ, Efstratiadis A (1993) Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r). Cell 75:59-72
23. Hise MK, Li L, Mantzouris N, Rohan RM (1995) Differential mRNA expression of insulin-like growth factor system during renal injury and hypertrophy. Am J Physiol 269:F817-F824
24. Lee DY, Park SK, Yorgin PD, Cohen P, Oh Y, Rosenfeld RG (1994) Alteration in insulin-like growth factor-binding proteins (IGFBPs) and IGFBP-3 protease activity in serum and urine from acute and chronic renal failure. J Clin Endocrinol Metab 79:1376-1382
25. Powell DR, Liu F, Baker BK, Hinzt RL, Kale A, Suwanichkul A, Durham SK (2000) Effect of chronic renal failure and growth hormone therapy on the insulin-like growth factors and their binding proteins. Pediatr Nephrol 14:579-583
26. Tsao T, Wang J, Fervenza FC, Vu TH, Jin IH, Hoffman AR, Rabkin R (1995) Renal growth hormone-insulin-like growth factor-I system in acute renal failure. Kidney Int 47:1658-1668
27. Sheikh MS, Shao ZM, Hussain A, Clemmons DR, Chen JC, Roberts CT Jr, LeRoith D, Fontana JA (1993) Regulation of insulin-like growth factor-binding-protein-1, 2, 3, 4, 5, and 6: synthesis, secretion, and gene expression in estrogen receptor-negative human breast carcinoma cells. J Cell Physiol 155: 556-567
28. Bradshaw SL, Han VK (1993) Hormonal regulation of astroglial insulin-like growth factor (IGF)-binding protein gene expression by IGFs and insulin. Endocrinology 133:1767-1777
29. Boisclair YR, Yang YW, Stewart JM, Rechler MM (1994) Insulin-like growth factor-I and insulin stimulate the synthesis of IGF-binding protein-2 in a human embryonic kidney cell line. Growth Regul 4:136-146
30. Langford K, Nicolaides K, Miell JP (1998) Maternal and fetal insulin-like growth factors and their binding proteins in the second and third trimesters of human pregnancy. Hum Reprod 13:1389-1393
31. Jones JI, Clemmons DR (1995) Insulin-like growth factors and their binding proteins: biological actions. Endocr Rev 16:3-34
32. Wood TL, Rogler LE, Czick ME, Schuller AG, Pintar JE (2000) Selective alterations in organ sizes in mice with a targeted disruption of the insulin-like growth factor binding protein-2 gene. Mol Endocrinol 14:1472-1482
33. Ruoslahti E, Pierschbacher MD (1987) New perspectives in cell adhesion: RGD and integrins. Science 238:491-497
34. Allan GJ, Flint DJ, Darling SM, Geh J, Patel K (2000) Altered expression of insulin-like growth factor-1 and insulin like growth factor binding proteins-2 and 5 in the mouse mutant Hypodactyly (Hd) correlates with sites of apoptotic activity. Anat Embryol (Berl) 202:1-11
35. Baker NL, Russo CV, Bernard O, D'Ercole AJ, Werther GA (1999) Interactions between bcl-2 and the IGF system control apoptosis in the developing mouse brain. Brain Res Dev Brain Res 118:109-118
36. Rajah R, Valentinis B, Cohen P (1997) Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta1 on programmed cell death through a p53- and IGF-independent mechanism. J Biol Chem 272:12181-12188
37. Gill ZP, Perks CM, Newcomb PV, Holly JM (1997) Insulin-like growth factor-binding protein (IGFBP-3) predisposes breast cancer cells to programmed cell death in a non-IGF-dependent manner. J Biol Chem 272:25602-25607