Solution Structure of an O6-[4-oxo-4-(3-Pyridyl)butyl]guanine Adduct in an 11mer DNA Duplex: Evidence for Formation of a Base Triplex

Biochemistry

Volumn 42, Issue 45, 2003, Pages 13134-13144

  Peterson, Lisa A ^a   Vu, Choua ^a   Hingerty, Brian E ^b   Broyde, Suse ^c   Cosman, Monique ^d  

^a UNIVERSITY OF MINNESOTA   (United States)

^b OAK RIDGE NATIONAL LABORATORY   (United States)

^c NEW YORK UNIVERSITY   (United States)

^d LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTATIONAL METHODS; DNA; HYDROGEN BONDS; MELTING; METABOLISM; MOLECULAR STRUCTURE; MUTAGENESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEINS; PROTONS; TUMORS;

MOLECULAR MECHANICS;

BIOCHEMISTRY;

6 O [4 OXO 4 (3 PYRIDYL)BUTYL]GUANINE; DOUBLE STRANDED DNA; GUANINE DERIVATIVE; NITROSAMINE; PURINE; TOBACCO SMOKE; UNCLASSIFIED DRUG; DNA; DRUG DERIVATIVE; GUANINE; HETERODUPLEX; INTERCALATING AGENT; O(6) (4 OXO 4 (3 PYRIDYL)BUTYL)GUANINE; O(6)-(4-OXO-4-(3-PYRIDYL)BUTYL)GUANINE; OLIGODEOXYRIBONUCLEOTIDE; TRIPLEX DNA;

ARTICLE; BASE PAIRING; CANCER RISK; CARCINOGENESIS; COVALENT BOND; DNA SEQUENCE; DNA STRUCTURE; HYDROGEN BOND; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; TEMPERATURE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; CONFORMATION; DNA ADDUCT; DNA BASE COMPOSITION; METHODOLOGY; SOLUTION AND SOLUBILITY; THERMODYNAMICS; ULTRAVIOLET SPECTROPHOTOMETRY; X RAY CRYSTALLOGRAPHY;

NICOTIANA TABACUM;

BASE COMPOSITION; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; DNA; DNA ADDUCTS; GUANINE; INTERCALATING AGENTS; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEIC ACID CONFORMATION; NUCLEIC ACID HETERODUPLEXES; OLIGODEOXYRIBONUCLEOTIDES; SOLUTIONS; SPECTROPHOTOMETRY, ULTRAVIOLET; THERMODYNAMICS;

EID: 0242569207     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi035217v     Document Type: Article

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