Inhibitory effect and mechanism of action of sanggenon C on human polymorphonuclear leukocyte adhesion to human synovial cells

Acta Pharmacologica Sinica

Volumn 23, Issue 2, 2002, Pages 138-142

  Li, Liang Cheng ^a   Shen, Fang ^a   Hou, Qi ^a   Cheng, Gui Fang ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Adhesions; Neutrophils; NF kappa B; Sanggenon C; Synovial membrane

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; MESSENGER RNA; MORUS CATHAYANA EXTRACT; PLANT EXTRACT; SANGGENON C; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; BENZOFURAN DERIVATIVE; CHROMONE DERIVATIVE; SANGGENONE C;

ARTICLE; CELL ADHESION; COLORIMETRY; CONCENTRATION RESPONSE; DRUG MECHANISM; DRUG STRUCTURE; ELECTROPHORETIC MOBILITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; LEUKOCYTE ADHERENCE; NEUTROPHIL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; CELL CULTURE; CELL SEPARATION; CHEMISTRY; CYTOLOGY; DRUG EFFECT; MALE; METABOLISM; MULBERRY; PLANT ROOT; SYNOVIUM;

BENZOFURANS; CELL ADHESION; CELL SEPARATION; CELLS, CULTURED; CHROMONES; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MALE; MORUS; NEUTROPHILS; NF-KAPPA B; PLANT ROOTS; SYNOVIAL MEMBRANE; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1;

EID: 0036163131     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Soluble intercellular adhesion molecules in arthritis
2. Effect of cytokine-induced soluble ICAM-1 from human synovial cells on synovial cell-lymphocyte adhesion
3. Synovial fluid cytokines in patients with rheumatoid arthritis or other arthritic lesions
4. Interleukin-8, interleukin-10, intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 expressing levels are higher in synovial tissue from patients with rheumatoid arthritis than in osteoarthritis
5. Proinflammatory cytokines enhance human synoviocyte expression of functional intercellular adhesion molecule-1 (ICAM-1)
6. Spontaneous production of an interleukin 1-like factor by cloned rheumatoid synovial cells in long-term culture
7. Fibronectin-mediated cell adhesion is required for induction of 92-kDa type IV collagenase/gelatinase (MMP-9) gene expression during macrophage differentiation
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9. Isolation of mononuclear cells and granulocytes from human blood. Isolation of mononuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g
10. Isolation and culture of rat synovial cell
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12. The inducing effect of inflammation mediators on the activation of NF-κB of mouse peritoneal macrophage
13. Inhibitory effects of hydrocortisone on human polymorphonuclear leukocyte adhesion to human synovial cell
14. Characterization of the promoter for vascular cell adhesion molecule-1 (VCAM-1)