Embryo-lethal and teratogenic effect of the new platinum compound DPR in pregnant mice

Archives of Toxicology

Volumn 77, Issue 10, 2003, Pages 584-590

  Ognio, Emanuela ^a   Lapide, Maddalena ^a   Ottone, Massimo ^a   Mandys, Václav ^b,c   Peterka, Miroslav ^c   Parodi, Brunella ^d   Viale, Maurizio ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b CHARLES UNIVERSITY   (Czech Republic)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Czech Republic)

^d UNIVERSITY OF GENOA   (Italy)

Author keywords

DPR; Embryotoxicity; Mouse; Teratogenicity

Indexed keywords

CISPLATIN [2 (DIETHYLAMINO)ETHYL 4 AMINOBENZOATE]; CISPLATIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CLEFT PALATE; CONTROLLED STUDY; DOSE RESPONSE; EMBRYO; EMBRYO DEATH; EMBRYO DEVELOPMENT; EMBRYO GROWTH; EMBRYOTOXICITY; FEMALE; FETOTOXICITY; FETUS; FETUS MALFORMATION; FETUS WEIGHT; GESTATIONAL AGE; GROWTH RETARDATION; HISTOGENESIS; KIDNEY MALFORMATION; KIDNEY PELVIS; MOUSE; NONHUMAN; OMPHALOCELE; ORGANOGENESIS; OSSIFICATION; PRENATAL DEVELOPMENT; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; RIB MALFORMATION; SKELETON MALFORMATION; STERNUM; SURVIVAL; TERATOGENICITY; WEIGHT GAIN;

ABNORMALITIES, DRUG-INDUCED; ANIMALS; ANTINEOPLASTIC AGENTS; BONE AND BONES; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FETAL DEATH; FETUS; INJECTIONS, INTRAPERITONEAL; MICE; ORGANOPLATINUM COMPOUNDS; PREGNANCY; PROCAINE; VISCERA;

ANIMALIA;

EID: 0242551871     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-003-0494-3     Document Type: Article

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