Variants of the CD40 ligand gene are not associated with increased susceptibility to tuberculosis in West Africa

Immunogenetics

Volumn 55, Issue 7, 2003, Pages 502-507

  Campbell, Sarah J ^a   Sabeti, Pardis ^a   Fielding, Katherine ^b   Sillah, Jackson ^c   Bah, Boubacar ^d   Gustafson, Per ^e   Manneh, Kebba ^f   Lisse, Ida ^e   Sirugo, Giorgio ^c   Bellamy, Richard ^a   Bennett, Steve ^b   Aaby, Peter ^e   McAdam, Keith P W J ^b   Bah Sow, Oumou ^d   Lienhardt, Christian ^c,g   Hill, Adrian V S ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c MEDICAL RESEARCH COUNCIL LABORATORIES   (Gambia)

^d Prog Natl Lutte Anti Tuberculeuse   (Guinea)

^e Statens Serum Institut   (Guinea-Bissau)

^f Natl TB/Leprosy Control Programme   (Gambia)

^g Laboratoire de Paludologie   (Senegal)

Author keywords

CD40 ligand; Genetic susceptibility; Polymorphism; Tuberculosis

Indexed keywords

CD40 ANTIGEN; CD40 LIGAND; MICROSATELLITE DNA;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ADULT; ARTICLE; CASE CONTROL STUDY; CHILD; CHROMOSOME XQ; CONTROLLED STUDY; EFFECTOR CELL; FEMALE; GAMBIA; GENE LINKAGE DISEQUILIBRIUM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; GUINEA; GUINEA-BISSAU; HUMAN; INFECTION SENSITIVITY; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE MARKER; MYCOBACTERIUM TUBERCULOSIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; TUBERCULOSIS;

AFRICA, WESTERN; CD40 LIGAND; GENETIC PREDISPOSITION TO DISEASE; HUMANS; TUBERCULOSIS; VARIATION (GENETICS);

ACTINOBACTERIA (CLASS); MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; UNCULTURED ACTINOMYCETE;

EID: 0242551851     PISSN: 00937711     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00251-003-0602-9     Document Type: Article

References (25)

1. Abecasis GR, Cookson WO (2000) GOLD-graphical overview of linkage disequilibrium. Bioinformatics 16:182-183
2. Barnhart B, Ford GS, Bhushan A, Song C, Covey LR (2000a) A polymorphic CD40 ligand (CD154) molecule mediates CD40-dependent signalling but interferes with the ability of soluble CD40 to functionally block CD154:CD40 interactions. Immunology 99:54-61
3. Barnhart B, Kosinski PA, Wang Z, Ford GS, Kiledjian M, Covey LR (2000b) Identification of a complex that binds to the CD154 3′ untranslated region: implications for a role in message stability during T cell activation. J Immunol 165:4478-4486
4. Bellamy R, Ruwende C, Corrah T, McAdam KP, Whittle HC, Hill AV (1998) Variations in the NRAMP1 gene and susceptibility to tuberculosis in West Africans. N Engl J Med 338:640-644
5. Bellamy R, Ruwende C, Corrah T, McAdam KP, Thursz M, Whittle HC, Hill AV (1999) Tuberculosis and chronic hepatitis B virus infection in Africans and variation in the vitamin D receptor gene. J Infect Dis 179:721-724
6. Bellamy R, Beyers N, McAdam KP, Ruwende C, Gie R, Samaai P, Bester D, Meyer M, Corrah T, Collin M, Camidge DR, Wilkinson D, Hoal-Van Helden E, Whittle HC, Amos W, van Helden P, Hill AV (2000) Genetic susceptibility to tuberculosis in Africans: a genome-wide scan. Proc Natl Acad Sci U S A 97:8005-8009
7. Bennett S, Lienhardt C, Bah-Sow O, Gustafson P, Manneh K, Del Prete G, Gomes V, Newport M, McAdam K, Hill A (2002) Investigation of environmental and host-related risk factors for tuberculosis in Africa. II. Investigation of host genetic factors. Am J Epidemiol 155:1074-1079
8. Campos-Neto A, Ovendale P, Bement T, Koppi TA, Fanslow WC, Rossi MA, Alderson MR (1998) CD40 ligand is not essential for the development of cell-mediated immunity and resistance to Mycobacterium tuberculosis. J Immunol 160:2037-2041
9. Comstock GW (1978) Tuberculosis in twins: a re-analysis of the Prophit survey. Am Rev Respir Dis 117:621-624
10. Day DJ, Speiser PW, White PC, Barany F (1995) Detection of steroid 21-hydroxylase alleles using gene-specific PCR and a multiplexed ligation detection reaction. Genomics 29:152-162
11. Dye C, Scheele S, Dolin P, Pathania V, Raviglione MC (1999) Consensus statement. Global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. WHO Global Surveillance and Monitoring Project. JAMA 282:677-686
12. Hinds DA, Risch N (1999) The ASPEX package: affected sib-pair exclusion mapping. ftp://lahmed.stanford.edu/pub/aspex/
13. Hopewell PC (1994) Overview of clinical tuberculosis. In Bloom BR (ed): Tuberculosis: pathogenesis, protection and control. American Society for Microbiology, Washington, DC, pp 25-46
14. Kooten C van (2000) Immune regulation by CD40-CD40-1 interactions - 2; Y2K update. Front Biosci 5:D880-693
15. Kruglyak L, Daly MJ, Reeve-Daly MP, Lander ES (1996) Parametric and nonparametric linkage analysis: a unified multipoint approach. Am J Hum Genet 58:1347-1363
16. Larkin R, Benjamin CD, Hsu YM, Li Q, Zukowski L, Silver RF (2002) CD40 ligand (CD154) does not contribute to lymphocyte-mediated inhibition of virulent mycobacterium tuberculosis within human monocytes. Infect Immun 70:4716-4720
17. Li CM, Campbell SJ, Bellamy R, McAdam K, Kumararatne D, Hill A, Lammas D (2002) Association of a polymorphism in the P2X7 gene with tuberculosis in a Gambian population. J Infect Dis 186:1458-1462
18. Lienhardt C, Bennett S, Del Prete G, Bah-Sow O, Newport M, Gustafson P, Manneh K, Gomes V, Hill A, McAdam K (2002) Investigation of environmental and host-related risk factors for tuberculosis in Africa. I. Methodological aspects of a combined design. Am J Epidemiol 155:1066-1073
19. Sabeti P, Usen S, Farhadian S, Jallow M, Doherty T, Newport M, Pinder M, Ward R, Kwiatkowski D (2002) CD40L association with protection from severe malaria. Genes Immun 3:286-291
20. Samten B, Thomas EK, Gong J, Barnes PF (2000) Depressed CD40 ligand expression contributes to reduced gamma interferon production in human tuberculosis. Infect Immun 68:3002-3006
21. Shimadzu M, Nunoi H, Terasaki H, Ninomiya R, Iwata M, Kanegasaka S, Matsuda I (1995) Structural organization of the gene for CD40 ligand: molecular analysis for diagnosis of X-linked hyper-IgM syndrome. Biochim Biophys Acta 1260:67-72
22. Siddiqa A, Sims-Mourtada JC, Guzman-Rojas L, Rangel R, Guret C, Madrid-Marina V, Sun Y, Martinez-Valdez H (2001) Regulation of CD40 and CD40 ligand by the AT-hook transcription factor AKNA. Nature 410:383-387
23. Singh SP, Mehra NK, Dingley HB, Pande JN, Vaidya MC (1983) Human leukocyte antigen (HLA)-linked control of susceptibility to pulmonary tuberculosis and association with HLA-DR types. J Infect Dis 148:676-681
24. Soler P, Boussaud V, Moreau J, Bergeron A, Bonnette P, Hance AJ, Tazi A (1999) In situ expression of B7 and CD40 costimulatory molecules by normal human lung macrophages and epithelioid cells in tuberculoid granulomas. Clin Exp Immunol 116:332-339
25. Yamauchi PS, Bleharski JR, Uyemura K, Kim J, Sieling PA, Miller A, Brightbill H, Schlienger K, Rea TH, Modlin RL (2000) A role for CD40-CD40 ligand interactions in the generation of type-1 cytokine responses in human leprosy. J Immunol 165:1506-1512