메뉴 건너뛰기




Volumn 28, Issue 11, 2003, Pages 1889-1902

SSR181507, a Dopamine D2 Receptor Antagonist and 5-HT 1A Receptor Agonist. II: Behavioral Profile Predictive of an Atypical Antipsychotic Activity

Author keywords

5 HT1A agonist; Antidepressant anxiolytic; Atypical antipsychotic; D2 antagonist

Indexed keywords

(3 EXO) 8 BENZOYL N [(7 CHLORO 2,3 DIHYDRO 1,4 BENZODIOXIN 1 YL)METHYL] 8 AZABICYCLO[3.2.1]OCTANE 3 METHANAMINE; ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; DEXAMPHETAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE 2 RECEPTOR BLOCKING AGENT; HALOPERIDOL; SACCHARIN; SEROTONIN 1A AGONIST; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR; SL 88 0338; SSR 181507; UNCLASSIFIED DRUG;

EID: 0242550590     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1300261     Document Type: Article
Times cited : (55)

References (44)
  • 1
    • 0024549249 scopus 로고
    • The nature and prevalence of depression in chronic schizophrenic in-patients
    • Barnes TR, Curson DA, Liddle PF, Patel M (1989). The nature and prevalence of depression in chronic schizophrenic in-patients. Br J Psychiatry 154: 488-491.
    • (1989) Br J Psychiatry , vol.154 , pp. 488-491
    • Barnes, T.R.1    Curson, D.A.2    Liddle, P.F.3    Patel, M.4
  • 2
    • 0018647518 scopus 로고
    • Effect of drugs influencing central serotonergic mechanisms on haloperidol-induced catalepsy
    • Balsara JJ, Jadhav JH, Chandorkar AG (1979). Effect of drugs influencing central serotonergic mechanisms on haloperidol-induced catalepsy. Psychopharmacology 62: 67-69.
    • (1979) Psychopharmacology , vol.62 , pp. 67-69
    • Balsara, J.J.1    Jadhav, J.H.2    Chandorkar, A.G.3
  • 3
    • 0034745153 scopus 로고    scopus 로고
    • 1A receptor in schizophrenia: A promising target for novel atypical neuroleptics?
    • 1A receptor in schizophrenia: a promising target for novel atypical neuroleptics? J Psychopharmacology 15: 37-46.
    • (2001) J Psychopharmacology , vol.15 , pp. 37-46
    • Bantick, R.A.1    Deakin, J.F.2    Grasby, P.M.3
  • 4
    • 0036053186 scopus 로고    scopus 로고
    • Do animal models of anxiety predict anxiolytic-like effects of antidepressants?
    • Borsini F, Podhorna J, Marazziti D (2002). Do animal models of anxiety predict anxiolytic-like effects of antidepressants? Psychopharmacology 163: 121-141.
    • (2002) Psychopharmacology , vol.163 , pp. 121-141
    • Borsini, F.1    Podhorna, J.2    Marazziti, D.3
  • 6
    • 0036268610 scopus 로고    scopus 로고
    • Relationship of the use of adjunctive pharmacological agents to symptoms and level of function in schizophrenia
    • Buchanan RW, Kreyenbuhl J, Zito JM, Lehman A (2002). Relationship of the use of adjunctive pharmacological agents to symptoms and level of function in schizophrenia. Am J Psychiatry 159: 1035-1043.
    • (2002) Am J Psychiatry , vol.159 , pp. 1035-1043
    • Buchanan, R.W.1    Kreyenbuhl, J.2    Zito, J.M.3    Lehman, A.4
  • 7
    • 0025607105 scopus 로고
    • Schizophrenics kill themselves too: A review of risk factors for suicide
    • Caldwell CB, Gottesman II (1990). Schizophrenics kill themselves too: a review of risk factors for suicide. Schizophr Bull 16: 571-589.
    • (1990) Schizophr Bull , vol.16 , pp. 571-589
    • Caldwell, C.B.1    Gottesman, I.I.2
  • 8
    • 0035110191 scopus 로고    scopus 로고
    • Barriers to progress - The impact of tolerability problems
    • Casey DE (2001). Barriers to progress - the impact of tolerability problems. Int Clin Psychopharmacol 16(Suppl 1): S15-S19.
    • (2001) Int Clin Psychopharmacol , vol.16 , Issue.1 SUPPL.
    • Casey, D.E.1
  • 10
    • 0036307453 scopus 로고    scopus 로고
    • Relapse and rehospitalisation rates in patients with schizophrenia: Effects of second generation antipsychotics
    • Csernansky JG, Schuchart EK (2002). Relapse and rehospitalisation rates in patients with schizophrenia: effects of second generation antipsychotics. CNS Drugs 16: 473-484.
    • (2002) CNS Drugs , vol.16 , pp. 473-484
    • Csernansky, J.G.1    Schuchart, E.K.2
  • 11
    • 0015596875 scopus 로고
    • On the mode of action of apomorphine
    • Costall B, Naylor RJ (1973). On the mode of action of apomorphine. Eur J Pharmacol 21: 350-361.
    • (1973) Eur J Pharmacol , vol.21 , pp. 350-361
    • Costall, B.1    Naylor, R.J.2
  • 12
    • 0031937466 scopus 로고    scopus 로고
    • Reversal of haloperidol-induced extrapyramidal side effects in cebus monkeys by 8-hydroxy-2-(di-n-propylamino)tetralin and its enantiomers
    • Christoffersen CL, Meltzer LT (1998). Reversal of haloperidol-induced extrapyramidal side effects in cebus monkeys by 8-hydroxy-2-(di-n-propylamino) tetralin and its enantiomers. Neuropsychopharmacology 18: 399-402.
    • (1998) Neuropsychopharmacology , vol.18 , pp. 399-402
    • Christoffersen, C.L.1    Meltzer, L.T.2
  • 13
    • 0035988519 scopus 로고    scopus 로고
    • Recent trends in antipsychotic combination therapy of schizophrenia and schizoaffective disorder: Implications for state mental health policy
    • Clark RE, Bartels SJ, Mellman TA, Peacock WJ (2002). Recent trends in antipsychotic combination therapy of schizophrenia and schizoaffective disorder: implications for state mental health policy. Schizophr Bull 28: 75-84.
    • (2002) Schizophr Bull , vol.28 , pp. 75-84
    • Clark, R.E.1    Bartels, S.J.2    Mellman, T.A.3    Peacock, W.J.4
  • 14
    • 0028990742 scopus 로고
    • 5-HT1A receptor agonists: Recent developments and controversial issues
    • De Vry J (1995). 5-HT1A receptor agonists: recent developments and controversial issues. Psychopharmacology 121: 1-26.
    • (1995) Psychopharmacology , vol.121 , pp. 1-26
    • De Vry, J.1
  • 15
    • 0023926874 scopus 로고
    • Use of conditioned taste aversion as a conflict model: Effects of anxiolytic drugs
    • Ervin GN, Cooper BR (1988). Use of conditioned taste aversion as a conflict model: effects of anxiolytic drugs. J Pharmacol Exp Ther 245: 137-146.
    • (1988) J Pharmacol Exp Ther , vol.245 , pp. 137-146
    • Ervin, G.N.1    Cooper, B.R.2
  • 16
    • 0032999945 scopus 로고    scopus 로고
    • The serotonin syndrome and its treatment
    • Gillman PK (1999). The serotonin syndrome and its treatment. J Psychopharmacol 13: 100-109.
    • (1999) J Psychopharmacol , vol.13 , pp. 100-109
    • Gillman, P.K.1
  • 19
    • 0022991462 scopus 로고
    • The enhancement by lithium of the 5-HT1A mediated serotonin syndrome produced by 8-OH-DPAT in the rat: Evidence for a post-synaptic mechanism
    • Goodwin GM, De Souza RJ, Wood AJ, Green AR (1986). The enhancement by lithium of the 5-HT1A mediated serotonin syndrome produced by 8-OH-DPAT in the rat: evidence for a post-synaptic mechanism. Psychopharmacology 90: 488-493.
    • (1986) Psychopharmacology , vol.90 , pp. 488-493
    • Goodwin, G.M.1    De Souza, R.J.2    Wood, A.J.3    Green, A.R.4
  • 20
    • 0035096016 scopus 로고    scopus 로고
    • 5-HT2A and D2 receptor blockade increases cortical DA release via 5-HT1A receptor activation: A possible mechanism of atypical antipsychotic-induced cortical dopamine release
    • Ichikawa J, Ishii H, Bonaccorso S, Fowler WL, O'Laughlin IA, Meltzer HY (2001). 5-HT2A and D2 receptor blockade increases cortical DA release via 5-HT1A receptor activation: a possible mechanism of atypical antipsychotic-induced cortical dopamine release. J Neurochem 76: 1521-1531.
    • (2001) J Neurochem , vol.76 , pp. 1521-1531
    • Ichikawa, J.1    Ishii, H.2    Bonaccorso, S.3    Fowler, W.L.4    O'Laughlin, I.A.5    Meltzer, H.Y.6
  • 21
    • 0023920285 scopus 로고
    • 8-Hydroxy-2-(di-n-propylamino) tetralin, a selective serotonin1A receptor agonist, blocks haloperidol-induced catalepsy by an action on raphe nuclei medianus and dorsalis
    • Invernizzi RW, Cervo L, Samanin R (1988). 8-Hydroxy-2-(di-n-propylamino) tetralin, a selective serotonin1A receptor agonist, blocks haloperidol-induced catalepsy by an action on raphe nuclei medianus and dorsalis. Neuropharmacology 27: 515-518.
    • (1988) Neuropharmacology , vol.27 , pp. 515-518
    • Invernizzi, R.W.1    Cervo, L.2    Samanin, R.3
  • 22
    • 0029658331 scopus 로고    scopus 로고
    • 5-HT2 antagonism and EPS benefits: Is there a causal connection?
    • Kapur S (1996). 5-HT2 antagonism and EPS benefits: is there a causal connection? Psychopharmacology 124: 35-39.
    • (1996) Psychopharmacology , vol.124 , pp. 35-39
    • Kapur, S.1
  • 23
    • 0035660215 scopus 로고    scopus 로고
    • 2 receptors and their role in atypical antipsychotic action: Still necessary and may even be sufficient
    • 2 receptors and their role in atypical antipsychotic action: still necessary and may even be sufficient. Biol Psychiatry 50: 873-883.
    • (2001) Biol Psychiatry , vol.50 , pp. 873-883
    • Kapur, S.1    Remington, G.2
  • 24
    • 0242513743 scopus 로고
    • The rat paradoxical sleep as a pharmacological test model
    • Herrmann WM (ed) Gustave Fisher: Stuttgart
    • Kleinlogel H (1982). The rat paradoxical sleep as a pharmacological test model. In: Herrmann WM (ed) EEG in Drug Research. Gustave Fisher: Stuttgart, pp 75-88.
    • (1982) EEG in Drug Research , pp. 75-88
    • Kleinlogel, H.1
  • 25
    • 0022399549 scopus 로고
    • Behavioral aspects of serotonin-dopamine interaction in the monkey
    • Korsgaard S, Gerlach J, Christensson E (1985). Behavioral aspects of serotonin-dopamine interaction in the monkey. Eur J Pharmacol 118: 245-252.
    • (1985) Eur J Pharmacol , vol.118 , pp. 245-252
    • Korsgaard, S.1    Gerlach, J.2    Christensson, E.3
  • 26
    • 0024478413 scopus 로고
    • Effects of 5-HT1A agonists and 5-HT2 antagonists on haloperidol-induced dyskinesias in squirrel monkeys: No evidence for reciprocal 5-HT-dopamine interaction
    • Liebman JM, Gerhardt SC, Gerber R (1989). Effects of 5-HT1A agonists and 5-HT2 antagonists on haloperidol-induced dyskinesias in squirrel monkeys: no evidence for reciprocal 5-HT-dopamine interaction. Psychopharmacology 97: 456-461.
    • (1989) Psychopharmacology , vol.97 , pp. 456-461
    • Liebman, J.M.1    Gerhardt, S.C.2    Gerber, R.3
  • 27
    • 0032868798 scopus 로고    scopus 로고
    • The role of serotonin in antipsychotic drug action
    • Meltzer HY (1999). The role of serotonin in antipsychotic drug action. Neuropsychopharmacology 21(2 Suppl): 106-115.
    • (1999) Neuropsychopharmacology , vol.21 , Issue.2 SUPPL. , pp. 106-115
    • Meltzer, H.Y.1
  • 28
    • 0032977410 scopus 로고    scopus 로고
    • The effects of clozapine, risperidone and olanzapine on cognitive function in schizophrenia
    • Meltzer HY, McGurk SR (1999). The effects of clozapine, risperidone and olanzapine on cognitive function in schizophrenia. Schizophr Bull 25: 233-255.
    • (1999) Schizophr Bull , vol.25 , pp. 233-255
    • Meltzer, H.Y.1    McGurk, S.R.2
  • 32
    • 0029822710 scopus 로고    scopus 로고
    • Effects of dopamine antagonists in a two-way active avoidance procedure in rats: Interactions with 8-OH-DPAT, ritanserin, and prazosin
    • Prinssen EP, Kleven MS, Koek W (1996). Effects of dopamine antagonists in a two-way active avoidance procedure in rats: interactions with 8-OH-DPAT, ritanserin, and prazosin. Psychopharmacology 128: 191-197.
    • (1996) Psychopharmacology , vol.128 , pp. 191-197
    • Prinssen, E.P.1    Kleven, M.S.2    Koek, W.3
  • 33
    • 0032935962 scopus 로고    scopus 로고
    • Receptor pharmacology of neuroleptics: Relation to clinical effects
    • Richelson E (1999). Receptor pharmacology of neuroleptics: relation to clinical effects. J Clin Psychiatry 60(Suppl 10): 5-14.
    • (1999) J Clin Psychiatry , vol.60 , Issue.10 SUPPL. , pp. 5-14
    • Richelson, E.1
  • 34
    • 0019956229 scopus 로고
    • Risk factors for suicide in psychiatric patients
    • Roy A (1982). Risk factors for suicide in psychiatric patients. Arch Gen Psychiatry 39: 1089-1095.
    • (1982) Arch Gen Psychiatry , vol.39 , pp. 1089-1095
    • Roy, A.1
  • 35
    • 0018147735 scopus 로고
    • Inhibition of REM sleep by fluoxetine, a specific inhibitor of serotonin uptake
    • Slater IH, Jones GT, Moore RA (1978). Inhibition of REM sleep by fluoxetine, a specific inhibitor of serotonin uptake. Neuropharmacology 17: 383-389.
    • (1978) Neuropharmacology , vol.17 , pp. 383-389
    • Slater, I.H.1    Jones, G.T.2    Moore, R.A.3
  • 36
    • 0030007496 scopus 로고    scopus 로고
    • Differential effect of antipsychotics on place navigation of rats in the Morris water maze. A comparative study between novel and reference antipsychotics
    • Skarsfeldt T (1996). Differential effect of antipsychotics on place navigation of rats in the Morris water maze. A comparative study between novel and reference antipsychotics. Psychopharmacology 124: 126-133.
    • (1996) Psychopharmacology , vol.124 , pp. 126-133
    • Skarsfeldt, T.1
  • 37
    • 0034810016 scopus 로고    scopus 로고
    • Enhancement of cognitive performance in schizophrenia by addition of tandospirone to neuroleptic treatment
    • Sumiyoshi T, Matsui M, Nohara S, Yamashita I, Kurachi M, Sumiyoshi C et al (2001). Enhancement of cognitive performance in schizophrenia by addition of tandospirone to neuroleptic treatment. Am J Psychiatry 158: 1722-1725.
    • (2001) Am J Psychiatry , vol.158 , pp. 1722-1725
    • Sumiyoshi, T.1    Matsui, M.2    Nohara, S.3    Yamashita, I.4    Kurachi, M.5    Sumiyoshi, C.6
  • 38
    • 0034030291 scopus 로고    scopus 로고
    • Effect of adjunctive treatment with serotonin-1A agonist tandospirone on memory functions in schizophrenia
    • Sumiyoshi T, Matsui M, Yamashita I, Nohara S, Uehara T, Kurachi M et al (2000). Effect of adjunctive treatment with serotonin-1A agonist tandospirone on memory functions in schizophrenia. J Clin Psychopharmacol 20: 386-388.
    • (2000) J Clin Psychopharmacol , vol.20 , pp. 386-388
    • Sumiyoshi, T.1    Matsui, M.2    Yamashita, I.3    Nohara, S.4    Uehara, T.5    Kurachi, M.6
  • 39
    • 0034977625 scopus 로고    scopus 로고
    • Mental health care in Japan: Recognition and treatment of depression and anxiety disorders
    • Tajima O (2001). Mental health care in Japan: recognition and treatment of depression and anxiety disorders. J Clin Psychiatry 62(Suppl 13): 39-44.
    • (2001) J Clin Psychiatry , vol.62 , Issue.13 SUPPL. , pp. 39-44
    • Tajima, O.1
  • 40
    • 0026032408 scopus 로고
    • Antipsychotic-like profile of combined treatment with raclopride and 8-OH-DPAT in the rat: Enhancement of antipsychotic-like effects without catalepsy
    • Wadenberg ML, Ahlenius S (1991). Antipsychotic-like profile of combined treatment with raclopride and 8-OH-DPAT in the rat: enhancement of antipsychotic-like effects without catalepsy. J Neural Transm [Gen Sect] 83: 43-53.
    • (1991) J Neural Transm [Gen Sect] , vol.83 , pp. 43-53
    • Wadenberg, M.L.1    Ahlenius, S.2
  • 41
    • 0032888408 scopus 로고    scopus 로고
    • The conditioned avoidance response test re-evaluated: Is it a sensitive test for the detection of potentially atypical antipsychotics?
    • Wadenberg ML, Hicks PB (1999). The conditioned avoidance response test re-evaluated: is it a sensitive test for the detection of potentially atypical antipsychotics? Neurosci Behav Rev 23: 851-862.
    • (1999) Neurosci Behav Rev , vol.23 , pp. 851-862
    • Wadenberg, M.L.1    Hicks, P.B.2
  • 42
    • 0033624208 scopus 로고    scopus 로고
    • Dopamine D2 receptor occupancy predicts catalepsy and the suppression of conditioned avoidance response behavior in rats
    • Wadenberg ML, Kapur S, Soliman A, Jones C, Vaccarino F (2000). Dopamine D2 receptor occupancy predicts catalepsy and the suppression of conditioned avoidance response behavior in rats. Psychopharmacology 150: 422-429.
    • (2000) Psychopharmacology , vol.150 , pp. 422-429
    • Wadenberg, M.L.1    Kapur, S.2    Soliman, A.3    Jones, C.4    Vaccarino, F.5
  • 43
    • 0030611825 scopus 로고    scopus 로고
    • 5-HT1A receptors in lithium-induced conditioned taste aversion
    • Wegener G, Smith DF, Rosenberg R (1997). 5-HT1A receptors in lithium-induced conditioned taste aversion. Psychopharmacology 133: 51-54.
    • (1997) Psychopharmacology , vol.133 , pp. 51-54
    • Wegener, G.1    Smith, D.F.2    Rosenberg, R.3
  • 44
    • 0032230189 scopus 로고    scopus 로고
    • Effects of tandospirone on tardive dyskinesia and parkinsonian symptoms
    • Yoshida K, Sugita T, Higuchi H, Hishikawa Y (1998). Effects of tandospirone on tardive dyskinesia and parkinsonian symptoms. Eur Psychiatry 13: 421-422.
    • (1998) Eur Psychiatry , vol.13 , pp. 421-422
    • Yoshida, K.1    Sugita, T.2    Higuchi, H.3    Hishikawa, Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.