Protein Folding: Importance of the Anfinsen Cage

Current Biology

Volumn 13, Issue 22, 2003, Pages

  Ellis, R John ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 0242540367     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2003.10.051     Document Type: Review

References (18)

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3. Hartl, F.U. and Hayer-Hartl, M. (2002). Molecular chaperones in the cytosol: from nascent chain to folded protein. Science 295, 1852-1858.
4. Brinker, A., Pfeifer, G., Kerner, M.J., Naylor, D.J., Hartl, F.U. and Hayer-Hartl, M. (2001). Dual function of protein confinement in chaperonin-assisted protein folding. Cell 707, 223-233.
5. Ellis, R.J. (2001). Molecular chaperones: inside and outside the Anfinsen cage. Curr. Biol. 11, R1038-R1040.
6. Houry, W.A., Frishman, D., Eckerskorn, C., Lottspeich, F., and Hartl F.U. (1999). Identification of in vivo substrates of the chaperonin GroEL. Nature 402, 147-154.
7. Chaudhuri, T.K., Farr, G.W., Fenton, W.A., Rospert, S. and Horwich, A.L. (2001). GroEL/GroES-mediated folding of a protein too large to be encapsulated. Cell 707, 235-246.
8. Farr, G.W., Fenton, W.A., Chaudhuri, T.K., Clare, D.L., Saibil, H.R. and Horwich, A.L. (2003). Folding with and without encapsulation by cis-and trans-only GroEL-GroES complexes. EMBO J. 22, 3220-3230.
9. Takagi, F., Koga, N. and Takada, S. (2003). How protein thermodynamics and folding are altered by the chaperonin cage: molecular simulations. Proc. Natl. Acad. Sci. USA 100, 11367-11372.
10. Ellis, R.J. (1996). Revisiting the Anfinsen cage. Fold. Des. 1, R9-R15.
11. Martin, J., and Hartl, F.U. (1997). The effect of macromolecular crowding on chaperonin-mediated protein folding. Proc. Natl. Acad. Sci. USA 94, 1107-1112.
12. Elcock, A.H. (2003). Atomic-level observations of macromolecular crowding effects: escape of a protein from the GroEL cage. Proc. Natl. Acad. Sci. USA 100, 2340-2344.
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