Vitamin E TPGS used in the solvent extraction/evaporation technique for fabrication of polymeric nanospheres of an antineoplastic drug paclitaxel (taxol®) for cancer chemotherapy

American Society of Mechanical Engineers, Bioengineering Division (Publication) BED

Volumn 50, Issue , 2001, Pages 187-188

  Mu, Li ^a   Feng, Si Shen ^a,b   Kiang, Thai Wee ^b  

^a INSTITUTE OF MATERIALS RESEARCH AND ENGINEERING   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOTHERAPY; EMULSIONS; EVAPORATION; LIGHT SCATTERING; PARTICLE SIZE ANALYSIS; SCANNING ELECTRON MICROSCOPY; SOLVENT EXTRACTION; TUMORS;

EMULSIFIERS; NANOSPHERES;

VITAMINS;

EID: 0242525273     PISSN: 10716947     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (6)

1. http://www.cnn.com/HEALTH/cancer/9910/27/taxol.approval/index.html.
2. Panchagnula R, 1998, "Pharmaceutical aspects of paclitaxel," Int. J. Pharm., 172, pp. 1-15.
3. Liggins, R. T., Amours, S. D., Demetrick, J. S., Machan, L. S. and Burt H. M., 2000, "Paclitaxel loaded poly(L-lactic acid) microspheres for the prevention of intraperitoneal carcinomatosis after a surgical repair and tumor cell spill," Biomaterials 21, pp. 1959-1969.
4. Murakami, H., Kawashima, Y., Niwa, T., Hino, T., Takeuchi, H. and Kobayashi, M., 1997, "Influence of the degrees of hydrolyzation and polymerization of poly(vinylalcohol) on the preparation and properties of poly(DL-lactide-co-glycolide) nanoparticle," Int. J. Pharm., 149, pp. 43-49.
5. ®) from Nanospheres of Biodegradable Polymers," J. Control Release, (in press).
6. Bridgers, A., 1998, "Vitamin E TPGS Enhances the Absorption of a Model HIV Protease Inhibitor by Inhibiting an Apically Polarized Efflux System," Pharm. Sci. 1 (1), S 76.