Genetic susceptibility to neural tube defect pregnancy varies with offspring phenotype

Clinical Genetics

Volumn 64, Issue 5, 2003, Pages 424-428

  Relton, Caroline L ^a   Wilding, C S ^a   Jonas, P A ^b,c   Lynch, S A ^c   Tawn, E J ^a   Burn, J ^c  

^a WESTLAKES RESEARCH INSTITUTE   (United Kingdom)

^b WEST CUMBERLAND HOSPITAL   (United Kingdom)

^c Centre for Life   (United Kingdom)

Author keywords

GCPII; MTHFR; Neural tube defects; Polymorphisms; RFC 1

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CYTOSINE; FOLIC ACID; GAMMA GLUTAMYL HYDROLASE; REDUCED FOLATE CARRIER; TYROSINE;

ANENCEPHALUS; ARTICLE; CONTROLLED STUDY; EMBRYO DEVELOPMENT; FEMALE; FOLATE METABOLISM; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HEREDITY; HUMAN; MAJOR CLINICAL STUDY; NEURAL TUBE DEFECT; PHENOTYPE; POLYMERASE CHAIN REACTION; PREGNANCY; PRIORITY JOURNAL; PROGENY; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT; RISK FACTOR; SPINA BIFIDA;

BASE SEQUENCE; CARRIER PROTEINS; CASE-CONTROL STUDIES; COHORT STUDIES; FEMALE; GENE FREQUENCY; GENETIC HETEROGENEITY; GENETIC PREDISPOSITION TO DISEASE; GLUTAMATE CARBOXYPEPTIDASE II; HUMANS; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); NEURAL TUBE DEFECTS; ODDS RATIO; PHENOTYPE; POLYMORPHISM, GENETIC; PREGNANCY; RISK;

EID: 0242525248     PISSN: 00099163     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-0004.2003.00161.x     Document Type: Article

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