Synthesis and Characterization of δ-Atracotoxin-Ar1a, the Lethal Neurotoxin from Venom of the Sydney Funnel-Web Spider (Atrax robustus)

Biochemistry

Volumn 42, Issue 44, 2003, Pages 12933-12940

  Alewood, Dianne ^a   Birinyi Strachan, Liesl C ^b   Pallaghy, Paul K ^c,d   Norton, Raymond S ^c,e   Nicholson, Graham M ^b   Alewood, Paul F ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

^c CSIRO   (Australia)

^d UNIVERSITY OF MELBOURNE   (Australia)

^e WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

OXIDATIVE REFOLDING;

CHEMICAL BONDS; DRUG PRODUCTS; MASS SPECTROMETRY; NEUROLOGY; NUCLEAR MAGNETIC RESONANCE; SODIUM; SYNTHESIS (CHEMICAL); TOXICITY;

POLYPEPTIDES;

2 PROPANOL; ALPHA TOXIN; DELTA ATRACOTOXIN AR1A; GLUTATHIONE; NEUROTOXIN; NEUROTOXIN RECEPTOR SITE 3; POLYPEPTIDE; SCORPION VENOM; SODIUM CHANNEL; SODIUM ION; SPIDER VENOM; TOXIN; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL TISSUE; ARTICLE; ATRAX ROBUSTUS; CONTROLLED STUDY; DISULFIDE BOND; ENVENOMATION; HYPERPOLARIZATION; MASS SPECTROMETRY; MOLECULAR WEIGHT; NONHUMAN; OXIDATION; PATCH CLAMP; PHARMACOPHORE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN REFOLDING; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SODIUM CURRENT; SPIDER; SPINAL GANGLION; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ACTION POTENTIALS; AMINO ACID SEQUENCE; ANIMALS; CELLS, CULTURED; DRUG RESISTANCE; GANGLIA, SPINAL; MALE; MEMBRANE POTENTIALS; MOLECULAR SEQUENCE DATA; NEURONS, AFFERENT; NEUROTOXINS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PATCH-CLAMP TECHNIQUES; PEPTIDE BIOSYNTHESIS; RATS; RATS, WISTAR; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; SPIDER VENOMS; SPIDERS; TETRODOTOXIN;

ANIMALIA; ARANEAE; ATRAX ROBUSTUS; DIPLURIDAE; INSECTA; INVERTEBRATA; MAMMALIA; SCORPIONES;

EID: 0242507457     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi030091n     Document Type: Article

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