Detection of p53 Gene Mutations by Nonisotopic RNase Cleavage Assay as a Predictor of Poor Prognosis in Colorectal Cancers

Digestive Diseases and Sciences

Volumn 48, Issue 10, 2003, Pages 1984-1989

  Haseba, Masatoshi ^a   Hidaka, Shigekazu ^a   Tsuji, Takashi ^a   Yano, Hiroshi ^a   Komatsu, Hideaki ^a   Sawai, Terumitu ^a   Yasutake, Toru ^a   Nakagoe, Tohru ^a   Tagawa, Yutaka ^b   Ayabe, Hiroyoshi ^a  

^a NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

Author keywords

Colorectal cancer; Mutation; Nonisotopic RNase cleavage assay; p53

Indexed keywords

PROTEIN P53; RIBONUCLEASE;

ADULT; AGED; ARTICLE; CANCER SCREENING; COLORECTAL CANCER; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; FEMALE; GENE MUTATION; GENETIC SCREENING; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; SINGLE STRAND CONFORMATION POLYMORPHISM;

AGED; COLORECTAL NEOPLASMS; FEMALE; GENES, P53; GENETIC TECHNIQUES; HUMANS; MALE; MIDDLE AGED; MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RIBONUCLEASES; SENSITIVITY AND SPECIFICITY; SURVIVAL ANALYSIS;

EID: 0242486786     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1026126522278     Document Type: Article

References (28)

1. Harris CC, Hollstein M: Clinical implications of the p53 tumor-suppressor gene. N Engl J Med 329:1318-1327, 1993
2. Levine AJ, Momand J, Finlay CA: The p53 tumor suppressor gene. Nature 351:453-456, 1991
3. Nigro JM, Baker SJ, Preisinger AC, Jessup JM, Hostetter R, Cleary K, Bigner SH, Davidson N, Baylin S, Devilee P, Glover T, Collins FS, Weston A, Modali R, Harris CC, Vogelstein B: Mutations in the p53 gene occur in diverse human tumour types. Nature 342:705-708, 1989
4. Hamelin R, Laurent-Puig P, Olschwang S, Jego N, Asselain B, Remvikos Y, Girodet J, Salmon RJ, Thomas G: Association of p53 mutations with short survival in colorectal cancer. Gastroenterology 106:42-48, 1994
5. Goh HS, Yao J, Smith DR: p53 point mutation and survival in colorectal cancer patients. Cancer Res 55:5217-5221, 1995
6. Pricolo VE, Finkelstein SD, Wu TT, Keller G, Bakrer A, Swalsky PA, Bland KI: Prognostic value of TP53 and K-ras-2 mutational analysis in stage III carcinoma of the colon. Am J Surg 171:41-46, 1996
7. Hardingham JE, Butler WJ, Roder D, Dobrovic A, Dymock RB, Sage RE, Roberts-Thomson IC: Somatic mutations, acetylator status, and prognosis in colorectal cancer. Gut 42:669-672, 1998
8. Lowe SW, Ruley HE, Jacks T, Housman DE: p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74:957-967, 1993
9. Lowe SW, Bodis S, McClatchey A, Remington L, Ruley HE, Fisher DE, Housman DE, Jacks T: p53 status and the efficacy of cancer therapy in vivo. Science 266:807-810, 1994
10. Benhattar J, Cerottini JP, Saraga E, Metthez G, Givel JC: p53 mutations as a possible predictor of response to chemotherapy in metastatic colorectal carcinomas. Int J Cancer 69:190-192, 1996
11. Lenz HJ, Hayashi K, Salonga D, Danenberg KD, Danenberg PV, Metzger R, Banerjee D, Bertino JR, Groshen S, Leichman LP, Leichman CG: p53 point mutations and thymidylate synthase messenger RNA levels in disseminated colorectal cancer: an analysis of response and survival. Clin Cancer Res 4:1243-1250, 1998
12. Zheng M, Wang H, Zhang H, Ou Q, Shen B, Li N, Yu B: The influence of the p53 gene on the in vitro chemosensitivity of colorectal cancer cells. J Cancer Res Clin Oncol 125:357-360, 1999
13. Orita M, Iwahana H, Kanazawa H, Hayashi K, Sekiya T: Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms. Proc Natl Acad Sci USA 86:2766-2770, 1989
14. Hamelin R, Jego N, Laurent-Puig P, Vidaud M, Thomas G: Efficient screening of p53 mutations by denaturing gradient gel electrophoresis in colorectal tumors. Oncogene 8:2213-2220, 1993
15. Nollau P, Wagener C: Methods for detection of point mutations: performance and quality assessment. IFCC Scientific Division, Committee on Molecular Biology Techniques. Clin Chem 43:1114-1128, 1997
16. Cotton RG: Slowly but surely towards better scanning for mutations. Trends Genet 13:43-46, 1997
17. Goldrick MM, Kimball GR, Liu Q, Martin LA, Sommer SS, Tseng JY: NIRCA: a rapid robust method for screening for unknown point mutations. Biotechniques 21:106-112, 1996
18. Prescott J, Patel H, Tillman S, McHugh T, Ralph D: Cleavage of double-stranded copy RNA by RNase 1 and RNase T1 provides a robust means to detect p53 gene mutations in clinical specimens. Electrophoresis 20:1149-1161, 1999
19. Macera MJ, Godec CJ, Sharma N, Verma RS: Loss of heterozygosity of the TP53 tumor suppressor gene and detection of point mutations by the non-isotopic RNAse cleavage assay in prostate cancer. Cancer Genet Cytogenet 108:42-47, 1999
20. Shen D, Wu Y, Chillar R, Vadgama JV: Missense alterations of BRCA1 gene detected in diverse cancer patients. Anticancer Res 20:1129-1132, 2000
21. Tommasi S, Abatangelo M, Lacalamita R, Montemurro S, Marzullo F, Paradiso A: Mutations spanning P53 exons 5-9 detected by non-isotopic RNAse cleavage assay and protein expression in human colon cancer. Cancer Genet Cytogenet 129:40-42, 2001
22. Dix B, Robbins P, Carrello S, House A, Iacopetta B: Comparison of p53 gene mutation and protein overexpression in colorectal carcinomas. Br J Cancer 70:585-590, 1994
23. Vet JA, Bringuier PP, Schaafsma HE, Witjes JA, Debruyne FM, Schalken JA: Comparison of P53 protein overexpression with P53 mutation in bladder cancer: clinical and biologic aspects. Lab Invest 73:837-843, 1995
24. Sjogren S, Inganas M, Norberg T, Lindgren A, Nordgren H, Holmberg L, Bergh J: The p53 gene in breast cancer: prognostic value of complementary DNA sequencing versus immunohistochemistry. J Natl Cancer Inst 88:173-182, 1996
25. Williams C, Norberg T, Ahmadian A, Ponten F, Bergh J, Inganas M, Lundeberg J, Uhlen M: Assessment of sequence-based p53 gene analysis in human breast cancer: messenger RNA in comparison with genomic DNA targets. Clin Chem 44:455-462, 1998
26. Hollstein M, Sidransky D, Vogelstein B, Harris CC: p53 mutations in human cancers. Science 253:49-53, 1991
27. Soussi T, Dehouche K, Beroud C: p53 website and analysis of p53 gene mutations in human cancer: forging a link between epidemilogy and carcinogenesis. Hum Mutat 15:105-113, 2000
28. Oliver M, Eeles R, Hollstein M, Khan MA, Harris CC, Hainaut P: The IARC TP53 database: New online mutation analysis and recommendations to users. Hum Mutat 19:607-614, 2002