Mutations spanning P53 exons 5-9 detected by non-isotopic RNAse cleavage assay and protein expression in human colon cancer

Cancer Genetics and Cytogenetics

Volumn 129, Issue 1, 2001, Pages 40-42

  Tommasi, Stefania ^a   Abatangelo, Marta ^a   Lacalamita, Rosanna ^a   Montemurro, Severino ^a   Marzullo, Francesco ^a   Paradiso, Angelo ^a  

^a NATIONAL CANCER INSTITUTE GIOVANNI PAOLO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; RIBONUCLEASE;

ARTICLE; ASSAY; COLON CANCER; CONTROLLED STUDY; EXON; GENE MUTATION; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SCREENING; TECHNIQUE; WESTERN BLOTTING;

COLONIC NEOPLASMS; EXONS; GENES, P53; HUMANS; MUTATION; RIBONUCLEASES;

EID: 0034909726     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-4608(01)00422-8     Document Type: Article

References (11)

1. Maintenance of genomic integrity by p53; complementary roles for the activated and non-activated p53
2. Mutations in the p53 tumor suppressor gene; Clues to cancer etiology and molecular pathogenesis
3. Role of p53 family in apoptosis
4. p53 point mutation and survival in colorectal cancer patients
5. Metastatic site and p53 primary tumor expression in previously untreated stage IV breast cancer patients
6. Thymidylate synthase and p53 primary tumor expression as predictive factors for advanced colorectal cancer patients
7. The p53 gene in breast cancer; Prognostic value of complementary DNA sequencing versus immunohistochemistry
8. Nirca; a rapid robust method for screening for unknown point mutations
9. Cleavage of double-stranded copy RNA by Rnase 1 and Rnase T1 provides a robust means to detect p53 gene mutations in clinical specimens
10. Loss of heterozygosity of the p53 tumor suppressor gene and detection of point mutations by the non-isotopic RNAse cleavage assay in prostate cancer
11. Extraction of DNA from small sections of frozen tissue with simultaneous histological examination