Possible role of amino acids, peptides, and sugar transporter in protein removal and innate lung defense

European Journal of Pharmacology

Volumn 479, Issue 1-3, 2003, Pages 263-267

  Mager, Sela ^a   Sloan, Jennifer ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Airway surface liquid; Amino acid; ATB0+; Innate lung defense; Mucociliary clearance; Peptide

Indexed keywords

AMINO ACID TRANSPORTER; CARRIER PROTEIN; GLUCOSE TRANSPORTER; GLYCOPROTEIN; PEPTIDE TRANSPORTER; POLYPEPTIDE; PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID TRANSPORT; BACTERIAL GROWTH; CELL MEMBRANE TRANSPORT; ENZYME DEGRADATION; GLUCOSE TRANSPORT; HYPOTHESIS; IMMUNITY; LUNG; LUNG ALVEOLUS; NONHUMAN; NUTRIENT AVAILABILITY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN TRANSPORT; RESPIRATORY EPITHELIUM; REVIEW;

EID: 0242469263     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2003.08.075     Document Type: Article

References (39)

1. Anderson J.M. Molecular structure of tight junctions and their role in epithelial transport. News Physiol. Sci. 16:2001;126-130.
2. Barth A.L., Pitt T.L. The high amino-acid content of sputum from cystic fibrosis patients promotes growth of auxotrophic Pseudomonas aeruginosa. J. Med. Microbiol. 45:1996;110-911.
3. Carraway M.S., Piantadosi C.A., Wright J.R. Alveolar proteinosis: a disease of mice and men. Am. J. Physiol. 280:2001;L377-L378.
4. Caughey G.H. Of mites and men: trypsin-like proteases in the lungs. Am. J. Respir. Cell Mol. Biol. 16:1997;621-628.
5. Cole A.M., Dewan P., Ganz T. Innate antimicrobial activity of nasal secretions. Infect. Immun. 67:1999;3267-3275.
6. Crandall E.D., Matthay M.A. Alveolar epithelial transport. Basic science to clinical medicine. Am. J. Respir. Crit. Care Med. 163:2001;1021-1029.
7. Deffebach M.E., Bryan C.J., Hoy C.M. Protein movement across cultured guinea pig trachea: specificity and effect of transcytosis inhibitors. Am. J. Physiol. 271:1996;L744-L752.
8. Dodoo A.N., Bansal S., Barlow D.J., Bennet F.C., Hider R.C., Lansley A.B., Lawrence M.J., Marriott C. Systematic investigations of the influence of molecular structure on the transport of peptides across cultured alveolar cell monolayers. Pharm. Res. 17:2000;7-14.
9. Folkesson H.G., Matthay M.A., Westrom B.R., Kim K.J., Karlsson B.W., Hastings R.H. Alveolar epithelial clearance of protein. J. Appl. Physiol. 80:1996;1431-1445.
10. Galietta L.J., Musante L., Romio L., Caruso U., Fantasia A., Gazzolo A., Romano L., Sacco O., Rossi G.A., Varesio L., Zegarra-Moran O. An electrogenic amino acid transporter in the apical membrane of cultured human bronchial epithelial cells. Am. J. Physiol. 275:1998;L917-L923.
11. Ganz T. Antimicrobial polypeptides in host defense of the respiratory tract. J. Clin. Invest. 109:2002;693-697.
12. Groneberg D.A., Nickolaus M., Springer J., Doring F., Daniel H., Fischer A. Localization of the peptide transporter PEPT2 in the lung: implications for pulmonary oligopeptide uptake. Am. J. Pathol. 158:2001;707-714.
13. Groneberg D.A., Eynott P.R., Doring F., Thai Dinh Q., Oates T., Barnes P.J., Chung K.F., Daniel H., Fischer A. Distribution and function of the peptide transporter PEPT2 in normal and cystic fibrosis human lung. Thorax. 57:2002;55-60.
14. Hastings R.H., Wright J.R., Albertine K.H., Ciriales R., Matthay M.A. Effect of endocytosis inhibitors on alveolar clearance of albumin, immunoglobulin G, and SP-A in rabbits. Am. J. Physiol. 266:1994;L544-L552.
15. Jiang X., Ingbar D.H., O'Grady S.M. Selectivity properties of a Na-dependent amino acid cotransport system in adult alveolar epithelial cells. Am. J. Physiol. 279:2000;L911-L915.
16. John T.A., Vogel S.M., Minshall R.D., Ridge K., Tiruppathi C., Malik A.B. Evidence for the role of alveolar epithelial gp60 in active transalveolar albumin transport in the rat lung. J. Physiol. 533:2001;547-559.
17. Johnson L.G., Cheng P.W., Boucher R.C. Albumin absorption by canine bronchial epithelium. J. Appl. Physiol. 66:1989;2772-2777.
18. Joris L., Quinton P.M. Evidence for electrogenic Na-glucose cotransport in tracheal epithelium. Pflugers Arch. 415:1989;118-120.
19. Kido H., Yokogoshi Y., Sakai K., Tashiro M., Kishino Y., Fukutomi A., Katunuma N. Isolation and characterization of a novel trypsin-like protease found in rat bronchiolar epithelial Clara cells. A possible activator of the viral fusion glycoprotein. J. Biol. Chem. 267:1992;13573-13579.
20. Kilburn K.H. A hypothesis for pulmonary clearance and its implications. Am. Rev. Respir. Dis. 98:1968;449-463.
21. Kim D.R., Sharmin S., Inoue M., Kido H. Cloning and expression of novel mosaic serine proteases with and without a transmembrane domain from human lung. Biochim. Biophys. Acta. 1518:2001;204-209.
22. Kim K.J., Borok Z., Crandall E.D. A useful in vitro model for transport studies of alveolar epithelial barrier. Pharm. Res. 18:2001;253-255.
23. Knowles M.R., Boucher R.C. Mucus clearance as a primary innate defense mechanism for mammalian airways. J. Clin. Invest. 109:2002;571-577.
24. Lester H.A., Mager S., Quick M.W., Corey J.L. Permeation properties of neurotransmitter transporters. Annu. Rev. Pharmacol. Toxicol. 34:1994;219-249.
25. Matsukawa Y., Yamahara H., Lee V.H., Crandall E.D., Kim K.J. Horseradish peroxidase transport across rat alveolar epithelial cell monolayers. Pharm. Res. 13:1996;1331-1335.
26. Matsukawa Y., Lee V.H., Crandall E.D., Kim K.J. Size-dependent dextran transport across rat alveolar epithelial cell monolayers. J. Pharm. Sci. 86:1997;305-309.
27. Matsukawa Y., Yamahara H., Yamashita F., Lee V.H., Crandall E.D., Kim K.J. Rates of protein transport across rat alveolar epithelial cell monolayers. J. Drug Target. 7:2000;335-342.
28. Palacin M., Borsani G., Sebastio G. The molecular bases of cystinuria and lysinuric protein intolerance. Curr. Opin. Genet. Dev. 11:2001;328-335.
29. Rose M.C., Nickola T.J., Voynow J.A. Airway mucus obstruction: mucin glycoproteins, MUC gene regulation and goblet cell hyperplasia. Am. J. Respir. Cell Mol. Biol. 25:2001;533-537.
30. Shah P.L., Hansell D., Lawson P.R., Reid K.B., Morgan C. Pulmonary alveolar proteinosis: clinical aspects and current concepts on pathogenesis. Thorax. 55:2000;67-77.
31. 0+. J. Biol. Chem. 274:1999;23740-23745.
32. 0+ in lung: possible role in luminal protein removal. Am. J. Physiol. 284:2003;L39-L49.
33. Takahashi M., Sano T., Yamaoka K., Kamimura T., Umemoto N., Nishitani H., Yasuoka S. Localization of human airway trypsin-like protease in the airway: an immunohistochemical study. Histochem. Cell Biol. 115:2001;181-187.
34. Thomas S.R., Ray A., Hodson M.E., Pitt T.L. Increased sputum amino acid concentrations and auxotrophy of Pseudomonas aeruginosa in severe cystic fibrosis lung disease. Thorax. 55:2000;795-797.
35. Trapnell B.C., Whitsett J.A. Gm-CSF regulates pulmonary surfactant homeostasis and alveolar macrophage-mediated innate host defense. Annu. Rev. Physiol. 64:2002;775-802.
36. van der Velden V.H., Hulsmann A.R. Peptidases: structure, function and modulation of peptide-mediated effects in the human lung. Clin. Exp. Allergy. 29:1999;445-456.
37. Whitsett J.A. Intrinsic and innate defenses in the lung: intersection of pathways regulating lung morphogenesis, host defense, and repair. J. Clin. Invest. 109:2002;565-569.
38. Wright E.M., Loo D.D., Panayotova-Heiermann M., Lostao M.P., Hirayama B.H., Mackenzie B., Boorer K., Zampighi G. 'Active' sugar transport in eukaryotes. J. Exp. Biol. 196:1994;197-212.
39. Yamaoka K., Masuda K., Ogawa H., Takagi K., Umemoto N., Yasuoka S. Cloning and characterization of the cDNA for human airway trypsin-like protease. J. Biol. Chem. 273:1998;11895-11901.