Nosocomial Pneumonia: Therapy Is Just Not Good Enough

Chest

Volumn 124, Issue 5, 2003, Pages 1632-1634

  Bauer, Torsten T ^a,b  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; AZTREONAM; LINEZOLID; VANCOMYCIN;

ANTIBIOTIC THERAPY; ARTIFICIAL VENTILATION; CLINICAL TRIAL; DRUG PENETRATION; EDITORIAL; ENDOTRACHEAL INTUBATION; HOSPITAL INFECTION; HUMAN; INFECTION RISK; INTENSIVE CARE UNIT; MORBIDITY; MORTALITY; NOSOCOMIAL PNEUMONIA; PENICILLIN RESISTANCE; PNEUMONIA; PRIORITY JOURNAL; RISK FACTOR; SELECTIVE DIGESTIVE DECONTAMINATION; SIDE EFFECT; STAPHYLOCOCCUS AUREUS; TECHNIQUE; TREATMENT OUTCOME;

EID: 0242468666     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.124.5.1632     Document Type: Editorial

References (20)

1. Chastre J, Fagon JY. Ventilator-associated pneumonia. Am J Respir Crit Care Med 2002; 165:867-903
2. Rello J, Ollendorf DA, Oster G, et al. Epidemiology and outcomes of ventilator-associated pneumonia in a large US database. Chest 2002; 122:2115-2121
3. Krueger WA, Lenhart FP, Neeser G, et al. Influence of combined intravenous and topical antibiotic prophylaxis on the incidence of infections, organ dysfunctions, and mortality in critically ill surgical patients: a prospective, stratified, randomized, double-blind, placebo-controlled clinical trial. Am J Respir Crit Care Med 2002; 166:1029-1037
4. Nathens AB, Marshall JC. Selective decontamination of the digestive tract in surgical patients: a systematic review of the evidence. Arch Surg 1999; 134:170-176
5. Esteban A, Frutos F, Tobin MJ, et al. A comparison of four methods of weaning patients from mechanical ventilation. N Engl J Med 1995; 323:345-350
6. Esteban A, Alía I, Tobin MJ, et al. Effect of spontaneous breathing trial duration on outcome of attempts to discontinue mechanical ventilation. Am J Respir Crit Care Med 1999; 159:512-518
7. Plant PK, Owen JL, Elliott MW. Early use of non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease on general respiratory wards: a multicentre randomised controlled trial. Lancet 2000; 355:1931-1935
8. Masip J, Betbese AJ, Paez J, et al. Non-invasive pressure support ventilation versus conventional oxygen therapy in acute cardiogenic pulmonary oedema: a randomised trial. Lancet 2000; 356:2126-2132
9. Nourdine K, Combes P, Carton MJ, et al. Does noninvasive ventilation reduce the ICU nosocomial infection risk? A prospective clinical survey. Intensive Care Med 1999; 25:567-573
10. Nava S, Ambrosino N, Clini E, et al. Noninvasive mechanical ventilation in the weaning of patients with respiratory failure due to chronic obstructive pulmonary disease: a randomised, controlled trial. Ann Intern Med 1998; 128:721-728
11. Ferrer M, Esquinas A, Arancibia F, et al. Noninvasive mechanical ventilation for persistent weaning failure: a randomized controlled trial. Am J Respir Crit Care Med 2003; 168:70-76
12. Heyland DK, Cook DJ, Dodek PM. Prevention of ventilator-associated pneumonia: current practice in Canadian intensive care units. J Crit Care 2002; 17:161-167
13. Kollef MH, Sherman G, Ward S, et al. Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients. Chest 1999; 115:462-474
14. Alvarez-Lerma F. Modification of empiric antibiotic treatment in patients with pneumonia acquired in the intensive care unit: ICU-Acquired Pneumonia Study Group. Intensive Care Med 1996; 22:387-394
15. Kollef MH. Inadequate antimicrobial treatment: an important determinant of outcome for hospitalized patients. Clin Infect Dis 2000; 31(Suppl 4):S131-S138
16. Wilcox MH. Efficacy of linezolid versus comparator therapies in Gram-positive infections. J Antimicrob Chemother 2003; 51(Suppl 2):II27-II35
17. Rubinstein E, Cammarata S, Oliphant T, et al. Linezolid (PNU-100766) versus vancomycin in the treatment of hospitalized patients with nosocomial pneumonia: a randomized, double-blind, multicenter study. Clin Infect Dis 2001; 32:402-412
18. Wunderink RG, Cammarata SK, Oilphant TH, et al. Linezolid versus vancomycin in the treatment of patients with nosocomial pneumonia: continuation of a randomized, double-blind multicenter study. Clin Ther 2003; 25:980-992
19. Stevens DL, Herr D, Lampiris H, et al. Linezolid versus vancomycin for the treatment of methicillin-resistant Staphylococcus aureus infections. Clin Infect Dis 2002; 34:1481-1490
20. Yamazumi T, Marshall SA, Wilke WW, et al. Comparison of the Vitek Gram-Positive Susceptibility 106 card and the MRSA-screen latex agglutination test for determining oxacillin resistance in clinical bloodstream isolates of Staphylococcus aureus. J Clin Microbiol 2001; 39:53-56