Evidence of Altered Neuropeptide Y Content and Neuropeptide Y1 Receptor Gene Expression in the Hypothalamus of Pregnant Transgenic Mice

Endocrinology

Volumn 144, Issue 11, 2003, Pages 4826-4830

  Oberto, Alessandra ^a   Mele, Paolo ^a   Zammaretti, Francesca ^a   Panzica, Giancarlo ^a   Eva, Carola ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; LEPTIN; MESSENGER RNA; NEUROPEPTIDE Y; NEUROPEPTIDE Y1 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; ESTRUS CYCLE; FEMALE; GENE EXPRESSION; HISTOCHEMISTRY; HORMONE RESISTANCE; HYPOTHALAMUS; HYPOTHALAMUS VENTROMEDIAL NUCLEUS; IMMUNOREACTIVITY; IN SITU HYBRIDIZATION; LACZ GENE; MOUSE; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; PROTEIN CONTENT; REPORTER GENE; THALAMUS MIDLINE NUCLEUS; TRANSGENIC MOUSE;

ANIMALS; ARCUATE NUCLEUS; BETA-GALACTOSIDASE; FEMALE; GENE EXPRESSION; HYPOTHALAMUS; MICE; MICE, TRANSGENIC; NEUROPEPTIDE Y; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PREGNANCY; PREGNANCY, ANIMAL; RECEPTORS, NEUROPEPTIDE Y; TISSUE DISTRIBUTION; VENTROMEDIAL HYPOTHALAMIC NUCLEUS;

EID: 0242468521     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2003-0197     Document Type: Article

References (30)

1. Pelleymounter MA, Cullen MJ, Baker MB, Hecht R, Winters D, Boone T, Collins F 1995 Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269:540-543
2. Chua Jr SC, Chung WK, Wu-Peng XS, Zhang Y, Liu SM, Tartaglia L, Leibel RL 1996 Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leprin) receptor. Science 271:994-996
3. Elmquist JK 2001 Hypothalamic pathways underlying the endocrine, autonomic and behavioral effects of leptin. Physiol Behav 74:703-708
4. Ahima RS, Osei SY 2002 Neuroendocrine regulation of appetite and energy balance. Curr Opin Endocrinol Diabetes 9:215-223
5. Kalra SP, Dube MG, Pu S, Xu B, Horvath TL, Kalra PS 1999 Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr Rev 20:68-100
6. Morton GJ, Schwartz MW 2001 The NPY/AgRP neuron and energy homeostasis. Int J Obes Relat Metab Disord 25:S56-S62
7. deq Uidt ME, Emson PC 1986 Distribution of neuropeptide Y-like immunoreactivity in the rat central nervous system. II. Immunohistochemical analysis. Neuroscience 18:545-618
8. Stanley BG, Kirkouli SE, Lampert S, Leibowitz SF 1986 Neuropeptide Y chronically injected into the hypothalamus: a powerful inducer of hyperfagia and obesity. Peptides 7:1189-1192
9. Stanley BG, Thomas WJ 1993 Feeding responses to perifornical hypothalamic injection of neuropeptide Y in relation to circadian rhythms of eating behavior. Peptides 14:475-481
10. Morley JE, Levine AS, Gosnell BA, Kneip J, Grace M 1987 Effect of neuropeptide Y on ingestive behaviors in the rat. Am J Physiol 252:R599-R609
11. Bouali SM, Fournier A, St-Pierre S, Jolicoeur FB 1995 Effects of NPY and NPY2-36 on body temperature and food intake following administration into hypothalamic nuclei. Brain Res Bull 36:131-135
12. Walter MJ, Scherrer JF, Flood JF, Morley JE 1994 Effects of localized injections of neuropeptide Y antibody on motor activity and other behaviors. Peptides 15:607-613
13. Inui A 1999 Neuropeptide Y feeding receptors: are multiple subtypes involved? Trends Pharmacol Sci 20:43-46
14. Mercer JG, Hoggard N, Williams LM, Lawrence CB, Hannah LT, Morgan PJ, Trayhurn P 1996 Coexpression of leptin receptor and preproneuropeptide Y mRNA in arcuate nucleus of mouse hypothalamus. J Neuroendocrinol 8: 733-735
15. Stephens TW, Basinski M, Bristow PK, Bue-Valleskey JM, Burgett SG, Craft L, Hale J, Hoffmann J, Hsiung HM, Kriauciunas A, MacKellar W, Rosteck PR, Schoner B, Smith D, Frank C, Tinsley FC, Zhang XY, Heiman M 1995 The role of neuropeptide Y in the antiobesity action of the obese gene product. Nature 377:530-532
16. Masuzaki H, Ogawa Y, Sagawa N, Hosoda K, Matsumoto T, Mise H, Nishimura H, Yoshimasa Y, Tanaka I, Mori T, Nakao K 1997 Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans. Nat Med 3:1029-1033
17. Bajoria R, Sooranna SR, Ward BS, Chatterjee R 2002 Prospective function of placental leptin at maternal-fetal interface. Placenta 23:103-115
18. 1 receptor 5′ upstream sequence directs cell-specific and developmentally regulated LacZ expression in transgenic mice CNS. Eur J Neurosci 10:3257-3268
19. 1 receptor gene expression in the hypothalamus of transgenic mice. Endocrinology 142:3774-3782
20. Franklin KBJ, Paxinos G 1997 The mouse brain in stereotaxic coordinates. San Diego, New York: Academic Press
21. Wisden W, Morris BJ 2002 In situ hybridization with oligonucleotide probes. In: Wisden W, Morris BJ, eds. In situ hybridization protocols for the brain. London: Academic Press; 9-34
22. 1 receptor gene in the medial amygdala of transgenic mice during pregnancy and after delivery. J Neurochem 82:1272-1281
23. Pelletier G, Désy L, Kerkeérian L, Coté J 1984 Immunocytochemical localization of neuropeptide Y (NPY) in the human hypothalamus. Cell Tissue Res 238:203-205
24. Plumari L, Viglietti-Panzica C, Allieri F, Honda S, Harada N, Balthazart J, Panzica GC 2002 Changes in the arginine-vasopressin immunoreactive systems in male mice lacking a functional aromatase gene. J Neuroendocrinol 14:971-978
25. Wisialowski T, Parker R, Preston E, Sainsbury A, Kraegen E, Herzog H, Cooney G 2000 Adrenalectomy reduces neuropeptide Y-induced insuline release and NPY receptor expression in the rat ventromedial hypothalamus. J Clin Invest 105:1253-1259
26. Heidel E, Plagemann A, Davidowa H 1999 Increased response to NPY of hypothalamic VMN neurons in postnatally overfed juvenile rats. Neuroreport 10:1827-1831
27. Xin XG, Huang XF 1998 Down-regulated NPY receptor subtype-5 mRNA expression in genetically obese mouse brain. Neuroreport 9:737-741
28. Guan XM, Yu H, Van der Ploeg LH 1998 Evidence of altered hypothalamic pro-opiomelanocortin/neuropeptide Y mRNA expression in tubby mice. Mol Brain Res 59:273-279
29. Guan XM, Yu H, Trumbauer M, Frazier E, Van der Ploeg LH, Chen H 1998 Induction of neuropeptide Y expression in dorsomedial hypothalamus of diet-induced obese mice. Neuroreport 9:3415-3419
30. Tobet SA, Henderson RG, Whiting PJ, Sieghart W 1999 Special relationship of γ-aminobutyric acid to the ventromedial nucleus of the hypothalamus during embryonic development. J Comp Neurol 405:88-98