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Volumn 90, Issue 5, 2003, Pages 898-903

Regulation of protease-activated receptor 1 (PAR 1) on platelets and responsiveness to thrombin receptor activating peptide (TRAP) during systemic inflammation in humans

Author keywords

Endotoxin; P selectin; Platelet; Protease activated receptor; Thrombin

Indexed keywords

ANTIBODY; ENDOTOXIN; PADGEM PROTEIN; PROTEINASE ACTIVATED RECEPTOR 1; PROTHROMBIN; PROTHROMBIN FRAGMENT 1 + 2; SPAN12 ANTIBODY; THROMBIN RECEPTOR ACTIVATING PEPTIDE; UNCLASSIFIED DRUG;

EID: 0242438137     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/th03-04-0245     Document Type: Article
Times cited : (32)

References (25)
  • 1
    • 0028080979 scopus 로고
    • Thrombin-receptor agonist peptides, in contrast to thrombin itself, are not full agonists for activation and signal transduction in human platelets in the absence of platelet-derived secondary mediators
    • Lau LF, Pumiglia K, Cote YP, et al. Thrombin-receptor agonist peptides, in contrast to thrombin itself, are not full agonists for activation and signal transduction in human platelets in the absence of platelet-derived secondary mediators. Biochem J 1994; 303: 391-400.
    • (1994) Biochem J , vol.303 , pp. 391-400
    • Lau, L.F.1    Pumiglia, K.2    Cote, Y.P.3
  • 2
    • 0026035523 scopus 로고
    • Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
    • Vu TK, Hung DT, Wheaton VI, et al. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 1991; 64: 1057-68.
    • (1991) Cell , vol.64 , pp. 1057-1068
    • Vu, T.K.1    Hung, D.T.2    Wheaton, V.I.3
  • 3
    • 0034921205 scopus 로고    scopus 로고
    • Protease-activated receptors in vascular biology
    • Coughlin SR. Protease-activated receptors in vascular biology. Thromb Haemost 2001; 86: 298-07.
    • (2001) Thromb Haemost , vol.86 , pp. 298-307
    • Coughlin, S.R.1
  • 4
    • 0033559805 scopus 로고    scopus 로고
    • Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin
    • Kahn ML, Nakanishi-Matsui M, Shapiro MJ, et al. Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin. J Clin Invest 1999; 103: 879-87.
    • (1999) J Clin Invest , vol.103 , pp. 879-887
    • Kahn, M.L.1    Nakanishi-Matsui, M.2    Shapiro, M.J.3
  • 5
    • 0028111114 scopus 로고
    • Changes in the structure and function of the human thrombin receptor during receptor activation, internalization, and recycling
    • Brass LF, Pizarro S, Ahuja M, et al. Changes in the structure and function of the human thrombin receptor during receptor activation, internalization, and recycling. J Biol Chem 1994; 269: 2943-52.
    • (1994) J Biol Chem , vol.269 , pp. 2943-2952
    • Brass, L.F.1    Pizarro, S.2    Ahuja, M.3
  • 6
    • 0031975435 scopus 로고    scopus 로고
    • The haematological manifestations of sepsis
    • Mammen EF. The haematological manifestations of sepsis. J Antimicrob Chemother 1998; 41 (Suppl A): 17-24.
    • (1998) J Antimicrob Chemother , vol.41 , Issue.SUPPL. A , pp. 17-24
    • Mammen, E.F.1
  • 7
    • 0031804584 scopus 로고    scopus 로고
    • Current drug treatment strategies for disseminated intravascular coagulation
    • De Jonge E, Levi M, Stoutenbeek CP, et al. Current drug treatment strategies for disseminated intravascular coagulation. Drugs 1998; 55: 767-77.
    • (1998) Drugs , vol.55 , pp. 767-777
    • De Jonge, E.1    Levi, M.2    Stoutenbeek, C.P.3
  • 8
    • 0031878665 scopus 로고    scopus 로고
    • Recombinant tumor necrosis factor receptor p75 fusion protein (TNFR:Fc) alters endotoxin-induced activation of the kinin, fibrinolytic, and coagulation systems in normal humans
    • DeLa Cadena RA, Majluf-Cruz A, Stadnicki A, et al. Recombinant tumor necrosis factor receptor p75 fusion protein (TNFR:Fc) alters endotoxin-induced activation of the kinin, fibrinolytic, and coagulation systems in normal humans. Thromb Haemost 1998; 80: 114-8.
    • (1998) Thromb Haemost , vol.80 , pp. 114-118
    • DeLa Cadena, R.A.1    Majluf-Cruz, A.2    Stadnicki, A.3
  • 9
    • 0036794013 scopus 로고    scopus 로고
    • Pharmacodynamics of active site-inhibited factor VIIa in endotoxin-induced coagulation in humans
    • Jilma B, Marsik C, Mayr F, et al. Pharmacodynamics of active site-inhibited factor VIIa in endotoxin-induced coagulation in humans. Clin Pharmacol Ther 2002; 72: 403-10.
    • (2002) Clin Pharmacol Ther , vol.72 , pp. 403-410
    • Jilma, B.1    Marsik, C.2    Mayr, F.3
  • 10
    • 0036097827 scopus 로고    scopus 로고
    • Acenocoumarol decreases tissue factor-dependent coagulation during systemic inflammation in humans
    • Hollenstein U, Homoncik M, Knobl P, et al. Acenocoumarol decreases tissue factor-dependent coagulation during systemic inflammation in humans. Clin Pharmacol Ther 2002; 71: 368-74.
    • (2002) Clin Pharmacol Ther , vol.71 , pp. 368-374
    • Hollenstein, U.1    Homoncik, M.2    Knobl, P.3
  • 12
    • 0035139160 scopus 로고    scopus 로고
    • Effects of anticoagulation on thrombopoietin release during endotoxemia
    • Jilma-Stohlawetz P, Folman CC, Von Dem Borne AE, et al. Effects of anticoagulation on thrombopoietin release during endotoxemia. J Lab Clin Med 2001; 137: 64-9.
    • (2001) J Lab Clin Med , vol.137 , pp. 64-69
    • Jilma-Stohlawetz, P.1    Folman, C.C.2    Von Dem Borne, A.E.3
  • 13
    • 0034192225 scopus 로고    scopus 로고
    • Effects of erythropoietin on platelet reactivity and thrombopoiesis in humans
    • Stohlawetz PJ, Dzirlo L, Hergovich N, et al. Effects of erythropoietin on platelet reactivity and thrombopoiesis in humans. Blood 2000; 95: 2983-9.
    • (2000) Blood , vol.95 , pp. 2983-2989
    • Stohlawetz, P.J.1    Dzirlo, L.2    Hergovich, N.3
  • 14
    • 0037297331 scopus 로고    scopus 로고
    • 6 decreases thrombin receptor activating peptide-induced P-selectin expression
    • 6 decreases thrombin receptor activating peptide-induced P-selectin expression. Blood Coagul Fibrinolysis 2003; 14: 131-8.
    • (2003) Blood Coagul Fibrinolysis , vol.14 , pp. 131-138
    • Homoncik, M.1    Jilma, B.2    Donham, D.C.3
  • 15
    • 0031041906 scopus 로고    scopus 로고
    • Thrombin receptors on human platelets. Initial localization and subsequent redistribution during platelet activation
    • Molino M, Bainton DF, Hoxie JA, et al. Thrombin receptors on human platelets. Initial localization and subsequent redistribution during platelet activation. J Biol Chem 1997; 272: 6011-7.
    • (1997) J Biol Chem , vol.272 , pp. 6011-6017
    • Molino, M.1    Bainton, D.F.2    Hoxie, J.A.3
  • 16
    • 0037369218 scopus 로고    scopus 로고
    • An intronic polymorphism in the PAR-1 gene is associated with platelet receptor density and the response to SFLLRN
    • Dupont A, Fontana P, Bachelot-Loza C, et al. An intronic polymorphism in the PAR-1 gene is associated with platelet receptor density and the response to SFLLRN. Blood 2003; 101: 1833-40.
    • (2003) Blood , vol.101 , pp. 1833-1840
    • Dupont, A.1    Fontana, P.2    Bachelot-Loza, C.3
  • 17
    • 0034867946 scopus 로고    scopus 로고
    • Platelet function analyzer (PFA-100): A tool to quantify congenital or acquired platelet dysfunction
    • Jilma B. Platelet function analyzer (PFA-100): A tool to quantify congenital or acquired platelet dysfunction. J Lab Clin Med 2001; 138: 152-63.
    • (2001) J Lab Clin Med , vol.138 , pp. 152-163
    • Jilma, B.1
  • 18
    • 0029011142 scopus 로고
    • Description of an in vitro platelet function analyzer-PFA-100
    • Kundu SK, Heilmann EJ, Sio R, et al. Description of an in vitro platelet function analyzer-PFA-100. Semin Thromb Hemost 1995; 21 (Suppl 2): 106-12.
    • (1995) Semin Thromb Hemost , vol.21 , Issue.SUPPL. 2 , pp. 106-112
    • Kundu, S.K.1    Heilmann, E.J.2    Sio, R.3
  • 19
    • 0034488936 scopus 로고    scopus 로고
    • Systemic inflammation increases shear stress-induced platelet plug formation measured by the PFA-100
    • Homoncik M, Blann AD, Hollenstein U, et al. Systemic inflammation increases shear stress-induced platelet plug formation measured by the PFA-100. Br J Haematol 2000; 111: 1250-2.
    • (2000) Br J Haematol , vol.111 , pp. 1250-1252
    • Homoncik, M.1    Blann, A.D.2    Hollenstein, U.3
  • 20
    • 0034613356 scopus 로고    scopus 로고
    • Protease-activated receptor-1 down-regulation: A mutant HeLa cell line suggests novel requirements for PAR1 phosphorylation and recruitment to clathrin-coated pits
    • Trejo J, Altschuler Y, Fu HW, et al. Protease-activated receptor-1 down-regulation: A mutant HeLa cell line suggests novel requirements for PAR1 phosphorylation and recruitment to clathrin-coated pits. J Biol Chem 2000; 275: 31255-65.
    • (2000) J Biol Chem , vol.275 , pp. 31255-31265
    • Trejo, J.1    Altschuler, Y.2    Fu, H.W.3
  • 21
    • 0029973981 scopus 로고    scopus 로고
    • In vivo tracking of platelets: Circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function
    • Michelson AD, Barnard MR, Hechtman HB, et al. In vivo tracking of platelets: Circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function. Proc Natl Acad Sci 1996; 93: 11877-82.
    • (1996) Proc Natl Acad Sci , vol.93 , pp. 11877-11882
    • Michelson, A.D.1    Barnard, M.R.2    Hechtman, H.B.3
  • 22
    • 0032926801 scopus 로고    scopus 로고
    • Effects of nitric oxide on platelet activation during plateletpheresis and in vivo tracking of biotinylated platelets in humans
    • Stohlawetz P, Horvath M, Pernerstorfer T, et al. Effects of nitric oxide on platelet activation during plateletpheresis and in vivo tracking of biotinylated platelets in humans. Transfusion 1999; 39: 506-14.
    • (1999) Transfusion , vol.39 , pp. 506-514
    • Stohlawetz, P.1    Horvath, M.2    Pernerstorfer, T.3
  • 24
    • 0024584776 scopus 로고
    • von Willebrand factor release induced by endotoxin
    • Gralnick HR, McKeown LP, Wilson OM, et al. von Willebrand factor release induced by endotoxin. J Lab Clin Med 1989; 113: 118-22.
    • (1989) J Lab Clin Med , vol.113 , pp. 118-122
    • Gralnick, H.R.1    McKeown, L.P.2    Wilson, O.M.3
  • 25
    • 0031757218 scopus 로고    scopus 로고
    • Differences in platelet alpha-granule release between normals and immune thrombocytopenic patients and between young and old platelets
    • Rinder HM, Tracey JB, Recht M, et al. Differences in platelet alpha-granule release between normals and immune thrombocytopenic patients and between young and old platelets. Thromb Haemost 1998; 80: 457-62.
    • (1998) Thromb Haemost , vol.80 , pp. 457-462
    • Rinder, H.M.1    Tracey, J.B.2    Recht, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.