Limited proteolysis reveals conformational changes in uncoupling protein-1 from brown adipose tissue mitochondria

Archives of Biochemistry and Biophysics

Volumn 420, Issue 1, 2003, Pages 40-45

  Huang, Shu Gui ^a,b  

^a UNIVERSITY OF MUNICH   (Germany)

^b AGY Therapeutics Inc   (United States)

Author keywords

Brown adipose tissue mitochondria; Chymotryptic digestion; Conformational change; Fluorescent nucleotide derivatives; Limited proteolysis; Nucleotide binding; Uncoupling protein 1

Indexed keywords

AMINO ACID; CHYMOTRYPSIN; DANSYL CHLORIDE; DIMER; GUANOSINE TRIPHOSPHATE; LYSINE; MITOCHONDRIAL PROTEIN; NUCLEOTIDE; NUCLEOTIDE DERIVATIVE; PHENYLALANINE; PROTON; TRYPSIN; UNCOUPLING PROTEIN 1;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING KINETICS; BROWN ADIPOSE TISSUE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; MITOCHONDRION; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTON TRANSPORT;

CRICETINAE;

EID: 0242438086     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.abb.2003.07.005     Document Type: Article

References (22)

1. Palmieri L., Runswick M.J., Fiermonte G., Walker J.E., Palmieri F. Bioenerg. Biomembr. 32:2000;67-77.
2. Giacobino J.P. Ann. NY Acad. Sci. 967:2002;398-402.
3. Klingenberg M. IUBMB Life. 52:2001;175-179.
4. Pecqueur C., Couplan E., Bouillaud F., Ricquier D. J. Mol. Med. 79:2001;48-56.
5. Nicholls D.G., Locke R.M. Physiol. Rev. 64:1984;1-64.
6. Lin C.S., Klingenberg M. FEBS Lett. 113:1980;299-303.
7. Flatmark T., Peterson J.I. Biochim. Biophys. Acta. 416:1975;53-103.
8. Himms-Hagen J. Annu. Rev. Physiol. 38:1976;315-351.
9. Nicholls D.G. Eur. J. Biochem. 62:1976;223-228.
10. Klingenberg M., Winkler E. EMBO J. 4:1985;3087-3092.
11. Klingenberg M. Biochemistry. 27:1988;781-791.
12. Lin C.S., Klingenberg M. Biochemistry. 21:1982;2950-2956.
13. Huang S.G., Klingenberg M. Biochemistry. 35:1996;7846-7854.
14. Huang S.G., Lin Q.S., Klingenberg M. J. Biol. Chem. 273:1998;859-864.
15. Eckerskorn C., Klingenberg M. FEBS Lett. 226:1987;166-170.
16. Fernandez M., Nicholls D.G., Rial E. Eur. J. Biochem. 164:1987;675-680.
17. Huang S.G., Klingenberg M. Biochemistry. 34:1995;349-360.
18. Klingenberg M., Mayer I., Appel M. Biochemistry. 24:1985;3650-3659.
19. Klingenberg M., Appel M. Eur. J. Biochem. 180:1989;123-131.
20. Neurath H., Hill R.L. The Proteins. third ed. 1977;Academic Press, New York.
21. Klingenberg M., Huang S.G. Biochim. Biophys. Acta. 1415:1999;271-296.
22. Echtay K.S., Winkler E., Bienengraeber M., Klingenberg M. Biochemistry. 39:2000;3311-3317.