Structure-activity relationship in the oxazolidinone-quinolone hybrid series: Influence of the central spacer on the antibacterial activity and the mode of action

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 23, 2003, Pages 4229-4233

  Hubschwerlen, Christian ^a   Specklin, Jean Luc ^a   Baeschlin, Daniel K ^a   Borer, Yves ^a   Haefeli, Sascha ^a   Sigwalt, Christine ^a   Schroeder, Susanne ^a   Locher, Hans H ^a  

^a Morphochem AG Basel   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

OXAZOLIDINONE DERIVATIVE; QUINOLONE DERIVATIVE;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL INFECTION; DRUG SPECIFICITY; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HOST PARASITE INTERACTION; PHARMACOPHORE; STRUCTURE ACTIVITY RELATION;

NEGIBACTERIA; POSIBACTERIA;

EID: 0242416198     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2003.07.028     Document Type: Article

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