Massive cardiac thrombosis and heparin-induced thrombocytopenia: A case report;Trombocitopenia associata a trombosi cardiaca massiva in corso di trattamento con eparina non frazionata: Descrizione di un caso clinico

Italian Heart Journal Supplement

Volumn 3, Issue 8, 2002, Pages 869-873

  De Piccoli, Bruno ^a,c   Martino, Anna ^b   Zuin, Guerrino ^a   Raviele, Antonio ^a  

^a Ospedale Umberto I   (Italy)

^b Ospedale Civile SS Giovanni e Paolo   (Italy)

^c NONE   (Italy)

Author keywords

Heparin; Thrombocytopenia; Thrombosis; Transesophageal echocardiography

Indexed keywords

ACETYLSALICYLIC ACID; HEPARIN; WARFARIN;

ADULT; ARTICLE; CASE REPORT; CLINICAL FEATURE; CORONARY ARTERY BYPASS GRAFT; DEEP VEIN THROMBOSIS; FEMALE; HEART INFARCTION; HEART MUSCLE REVASCULARIZATION; HUMAN; INTRACARDIAC THROMBOSIS; THROMBOCYTE COUNT; THROMBOCYTOPENIA; TRANSESOPHAGEAL ECHOCARDIOGRAPHY; CHEMICALLY INDUCED DISORDER; HEART DISEASE; MIDDLE AGED; THROMBOSIS;

FEMALE; HEART DISEASES; HEPARIN; HUMANS; MIDDLE AGED; THROMBOCYTOPENIA; THROMBOSIS;

EID: 0242364187     PISSN: 11294728     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Sculier JP, Coune A, Vandenbossche JC, Muller C. Intracardiac thrombosis associated with acute consumption coagulopathy. Cardiology 1987; 74: 58-61.
2. McIlraith DM, Mant MJ, Brien WF. Chronic consumptive coagulopathy due to intracardiac thrombus. Am J Med 1987; 82: 135-6.
3. Hanano M, Takahashi H, Arakawa K, et al. Consumption coagulopathy associated with left atrial thrombosis. Hematol Pathol 1991; 5: 27-31.
4. Levi M, de Jonge E, van der Poll T, ten Cate H. Disseminated intravascular coagulation. Thromb Haemost 1999; 82: 695-705.
5. Olbrich K, Wiersbitzky M, Wacke W, et al. Atypical heparin-induced thrombocytopenia complicated by intracardiac thrombus, effectively treated with ultra-low-dose rt-PA lysis and recombinant hirudin (Lepirudin). Blood Coagul Fibrinolysis 1998; 9: 273-7.
6. Warkentin TE, Levine MN, Hirsh J, et al. Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin. N Engl J Med 1995; 332: 1330-5.
7. Warkentin TE. Heparin-induced thrombocytopenia: a clinicopathologic syndrome. Thromb Haemost 1999; 82: 439-47.
8. Giaconi S, Zecchi C, Rocchi M, Tartarini G. Trombocitopenia indotta da eparina: descrizione di un caso clinico. Ital Heart J Suppl 2001; 2: 1016-9.
9. Fabris F, Luzzatto G, Stefani PM, Girolami B, Cella G, Girolami A, Hepapin-induced thrombocytopenia. Haematologica 2000; 85: 72-81.
10. Contrino J, Hair G, Kreutzer D, Rickles FR. In situ detection of tissue factor in vascular endothelial cells: correlation with the malignant phenotype of human breast disease. Nat Med 1996; 2: 209-15.
11. Hunt BJ, Parrat RN, Segal HC, Sheikh S, Kallis P, Yacoub M. Activation of coagulation and fibrinolysis during cardiothoracic operations. Ann Thorac Surg 1998; 65: 712-8.
12. Wilde JT. Hematological consequences of profound hypothermic circulatory arrest and aortic dissection. J Card Surg 1997; 12 (2 Suppl): 201-6.
13. Bick RL. Alterations of hemostasis associated with cardiopulmonary bypass: pathophysiology, prevention, diagnosis and management. Semin Thromb Hemost 1976; 3: 59-82.
14. Visentin GP, Ford SE, Scott JP, Aster RH. Antibodies from patients with heparin-induced thrombocytopenia/thrombosis are specific for platelet factor 4 complexed with heparin or bound to endothelial cells. J Clin Invest 1994; 93: 81-8.
15. Amiral J. Diagnostic tests in heparin-induced thrombocytopenia. Platelets 1997; 8: 68-72.
16. King DJ, Kelton JG. Heparin-associated thrombocytopenia. Ann Intern Med 1984; 100: 535-40.
17. Warkentin TE, Sheppard JA, Horsewood P, Simpson PJ, Moore JC, Kelton JG. Impact of the patient population on the risk for heparin-induced thrombocytopenia. Blood 2000; 96: 1703-8.
18. Vignon P, Gueret P, Francois B, Serhal C, Fermeaux V, Bensaid J. Acute limb ischemia and heparin-induced thrombocytopenia: the value of echocardiography in eliminating a cardiac source of arterial emboli. J Am Soc Echocardiogr 1996; 9: 344-7.
19. Lewis BE, Walenga JM, Wallis DE. Anticoagulation with Novastan (argatroban) in patients with heparin-induced thrombocytopenia and heparin-induced thrombocytopenia and thrombosis syndrome. Semin Thromb Hemost 1997; 23: 197-202.
20. Greinacher A, Janssens U, Berg G, et al. Lepirudin (recombinant hirudin) for parenteral anticoagulation in patients with heparin-induced thrombocytopenia. Heparin-Associated Thrombocytopenia Study (HAT) Investigators. Circulation 1999; 100: 587-93.
21. Wallis DE, Quintos R, Wehrmacher W, Messmore H. Safety of warfarin anticoagulation in patients with heparin-induced thrombocytopenia. Chest 1999; 116: 1333-8.
22. Matsuo T, Yamada T, Chikahira Y, Kadowaki S. Effect of aspirin on heparin-induced thrombocytopenia (HIT) in a patient requiring hemodialysis. Blut 1989; 59: 393-5.
23. Haas S, Walenga JM, Jeske WP, Fareed J, Heparin-induced thrombocytopenia: the role of platelet activation and therapeutic implications. Semin Thromb Hemost 1999; 25 (Suppl 1): 67-75.
24. Walenga JM, Jeske WP, Wallis DE, et al. Clinical experience with combined treatment of thrombin inhibitors and GP IIb/IIIa inhibitors in patients with HIT. Semin Thromb Hemost 1999; 25 (Suppl 1): 77-81.