Organ protective intensive care of organ donors;Die organprotektive intensivtherapie bei postmortalen Organspendern

Intensivmedizin und Notfallmedizin

Volumn 40, Issue 7, 2003, Pages 574-584

  Mauer, Dietmar ^a   Nehammer, K ^a   Bosebeck D ^b   Wesslau, C ^c  

^a Deutsche Stiftung Organtransplantation   (Germany)

^b Deutsche Stift Organtransplantation   (Germany)

^c Deutsche Stiftung Organtransplantation   (Germany)

Author keywords

ADH deficiency; Brain death; Catecholamine treatment; Homeostasis; Intensive care of organ donors

Indexed keywords

CATECHOLAMINE; CORTICOSTEROID; DESMOPRESSIN; VASOPRESSIN;

ASSISTED VENTILATION; BRAIN DEATH; DRUG INDICATION; HOMEOSTASIS; HUMAN; INTENSIVE CARE; ORGAN DONOR; ORGAN TRANSPLANTATION; PATHOPHYSIOLOGY; PATIENT POSITIONING; REVIEW; THERMOREGULATION;

EID: 0242362164     PISSN: 01753851     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00390-003-0441-9     Document Type: Review

References (75)

1. Ali MJ (1994) Essentials of Organ Donor Problems and their Management. Anesthesiology Clin North America 12:655-671
2. Ali MJ, Wood G, Gelb AW (1992) Organ Donor Problems and their Management. Can J Anaesth 39:A125
3. Bamberger CM, Schulte HM (1997) Glucocorticoide-Teil 1. Internist 38:366-370
4. Bhorade SM, Vigneswaran W, McCabe (2000) Liberalization of Donor criteria may expand the donor-pool without adverse consequence in lung. J Heart Lung Transplantation 19:1199-1204.
5. Bittner HB, Chen EP (1997) Brain Death Alters Cardiopulmonary Hemodynamics and Impairs Right Ventricular Power Reserve against an Elevation of Pulmonary Vascular Resistance. Chest 111:706-711
6. Bollaert P-E, Charpentier C, Levy B, Debouverle M, Audibert G, Larcan A (1998) Reversal of late septic shock with supraphysiologic dose of hydrocortisone. Crit Care Med 26:645-650
7. Briegel J, Forst H, Haller M, Schelling G, Kilger E, Kuprat G, Hemmer B, Hummel T, Lenhart A, Heyduck M, Stoll C, Peter K (1999) Stress doses of hydrocortisone reverse hyperdynamic septic shock: A prospective, randomized, double-blind, single-center study. Crit Care Med 27:723-732
8. Briegel J, Kellermann W, Forst H, Haller M, Bittl M, Hoffmann GE, Büchler M, Uhl W, Peter K (1994) Low-dose hydrocortisone infusion attenuate the systemic inflammatory response syndrome. Clin Investig 72:782-787
9. Cohen J, Chernov K, Ben-Shimon O (2002) Management of the brain-dead heart beating potential donor. IMAJ 4:243-246
10. Darby JM, Stein K, Grenvik A, Stuart SA (1989) Approach to Management of the Heartbeating "Brain-Dead" Organ Donor. JAMA 261:2222-2228
11. Deutsche Stiftung Organtransplantation (Hrsg) (2003) Organspende und Transplantation in Deutschland 2002, Neu-Isenburg, pp 6-17
12. Deutsche Stiftung Organtransplantation (Hrsg) (2003) Jahresbericht der Region Mitte 2002, Neu-Isenburg, pp 26-28
13. Deutsche Stiftung Organtransplantation (Hrsg) (2002) Organspende - Eine gemeinsame Aufgabe. Neu-Isenburg, Kapitel 5, pp 1-9
14. Dietrich H-J (2002) Bericht vom DAK 2002; HES 130/0,4: Volumenersatz ohne Beeinträchtigung der Nierenfuntion. Anästhesiologie & Intensivmedizin 43:646-647
15. Dowling RD, Williams P, Zenati M (1995) Infections and pathologic factors in the donor lung. J Thorac Cardiovasc Surg 109:1263-1264
16. Fisher AJ, Dark JH, Corris PA (1998) Improving donor lung evaluation: a new approach to increase organ supply for lung transplantation. Thorax 53:818-820
17. Fisher AJ, Donnelly SC, Hirani (1999) The effect of donor lung inflammation on outcoming human lung transplantation. Thorax 54:180
18. Fitzgerald RD (1997) Management of the brain-dead organ donor. Saudi J Kidney Dis Transplant 8:21-31
19. Follette D, Rudich S, Bonacci C, Allen R, Hoso A, Albertson T (1999) Importance of an aggressive multidisciplinary managment approach to optimize lung donor procurement. Transplant Proc 31:169-170
20. Follette DM, Rudich SM, Babcock WD (1997) Improved oxygenation and increased lung donor recovery with high-dose steroid administration after brain death. J Heart Lung Transplant 17:423-429
21. Garcia-Fages LC, Antolin M, Cabrer C, Talbot R, Alcaraz A, Lozano F, Manyalich M (1991) Effects of Substitutive Triiodthyronine Therapy on Intracellular Nucleotide Levels in Donor Organs. Transplant Proc 23:2495-2496
22. Goarin J-P, Cohen S, Riou B (1996) The Effects of Triiodothyronine on Hemodynamic Status and Cardiac Funktion in Potential Heart Donors. Anesth Analg 83:47-49
23. Halejcio-Delephont P, Siaghy EM (1998) Consequences of brain death on coronary blood flow and myocardial metabolism. Transplant Proc 30:2840-2841
24. Haverich A, Warnecke G, Fischer S (2002) Critical donor organs for heart and lung transplantation: Quantification of transplant qualitiy. Chir Gastroenterologie 18:18-23
25. Hebert PC, Wells G, Blajchman MA, Marshall J, Martini C, Pagliarello G, Tweedale M, Schweitzer I, Yetsir E (1999) A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. N Engl J Med 340:409-417
26. Holmquist M, RN; Chabalewski F (1999) A Critical Guiding Care of Organ Donors. Critical Care Nurse 19:84-98
27. Jeevanandam V, Todd B, Hellmann S, Eldridge C, McClurken J, Addonizio P (1993) Use of Triiodthyronine Replacement Therapy to Reverse Donor Myocardial Dysfunction: Creating a Larger Donor Pool. Transplant Proc 25:3305-3306
28. Jeevanandam V (1997) Triiodothyroine: Spectrum of Use in Heart Transplantation. Thyroid 7:139-145
29. Katz K, Lawler J, Wax J, O'Connor R, Nadkarni V (2000) Vasopressin pressor effects in critically ill children during evaluation for brain death and organ recovery. Resuscitation 47:33-40
30. Kinoshita Y, Yahata K, Yoshioka T, Onishi S, Sugimoto T (1990) Long-term renal preservation after brain death maintained with vasopressin and epinephrine. Transplant Int 3:15-18
31. Kolin A, Norris J (1984) Myocardial Damage from Acute Cerebral Lesions. Stroke 15:990-993
32. Kono T, Nishina T (1999) Usefulness of Low-Dose Dobutamine Stress Echocardiography for Evaluating Reversibility of Brain Death-Induced Myocardial Dysfunction. Am J Cardiol. 84:578-582
33. Lassie P, Sztark F, Thicoiepe M (1995) Donor Criteria for lung transplantation: a retrospective study. Transplant Proc 27:2532
34. MacLean A, Dunning J (1997) The retrieval of thoracic organs: donor assessment and management. Brit Med Bulletin 53:829-843
35. Macoviak JA, McDougall IR, Bayer MF (1986) Significance of thyroid dysfunction in human cardiac allograft procurement. Transplantation 43:824-826
36. Massei R, Martini C, Parma A, Cala (1993) Management of multiple organ donor: respiratory a metabolism-related problems. Minerva Anestesiologica 59:97
37. Matsumura Y, Okada Y, Shimada K (2002) Assessment of Brain-Dead Cadaver Donor for Lung Transplantation. Transplant Proc 34:2585-2586
38. McAdams DE, Bearden C, Headrick TR (1995) Use of thyroid replacement therapy in donor management. J of Transplant Coordination 5:117-120
39. Nagareda T, Kinoshita Y, Tanaka A, Hasuike Y, Terada N, Nishizawa Y, Fujita M (1989) Clinicopathological Study Of Livers From Brain-Dead Patients Treated With A Combination of Vasopressin And Epinehrine Transplantation 47:792-797
40. Nehammmer K (2000) Hormonsubstitution bei hirntoten Organspendern. Novartis, wissenschaftliche Dokumentation 2000
41. Novitzky D (1991). Triiodothyroine Replacement, the Euthyroid Sick Syndrome, and Organ Transplantation. Transplant Proc 23:2460-2462
42. Novitzky D, Cooper DK (1988) Results of hormonal therapy in human brain-dead potential organ donors. Transplant Proc 20:59-62
43. Novitzky D, Cooper DK, Chaffin JS (1990) Improved cardiac allograft function following trioiodothyronine therapy to both donor and recipient. Transplantation 49:311-316
44. Novitzky D, Cooper DKC, Morrell D, Isaacs S (1987) Triiodothyronine Depletion, and Inhibition of Oxidative Phosphorylation: Relevance to Management of Organ Donors. Transplant Proc 5:4110-4111
45. Novitzky D, Cooper DKC, Reichart B (1987) The Value of Hormonal Therapy in Improving Organ Viability In the Transplant Donor. Transplant Proc 19:2077-2088
46. Novitzky D, Cooper DKC, Reichhhart B (1987) Hemodynamik and metabolic responses to hormonal therapy in brain-dead potential organ donors. Transplantation 43:852-864
47. Novitzky D, Cooper DKC, Rose AG, Fraser RC, Barnard CW (1988) Change from Aerobic to Anaerobic Metabolism after Brain Death and Reversal Following Triiodothyroine Therapy. Transplantation 45:32-36
48. Novitzky D, Wicomb WN, Cooper DKC et al (1984) Elektrocardiographik, Hemodynamic and Endocrine Changes during Experimental Brain Death in the Chacma Baboon. Journal of Heart Transplant 4:63
49. Novitzky D (1996) The Role of Triiodothyronine in Cardiac Transplantation. Thyroid 5:531-536
50. Orlowsky JP (1993) Evidence that thyroxine (T4) is effective as a hemodynamic rescue agent in management of organ donors. Transplantation 55: 959-960
51. Pennefather SH, Bullock RE. (1993) Triiodothyronine treatment in brain-dead multiorgan donors - a controlled study. Transplantation 55: 1443-1447
52. Pennfather SH, Bullock RE (1995) Use of Low Dose Arginine Vasopressin To Support Brain-Dead Organ Donors. Transplantation 59:58-62
53. Pickett JA, Wheeldon D, Oduro A (1994) Multi-Organ Transplantation: donor managment. Cur Op Anaesth 7:80-83
54. Powner DJ, Darby JM (2000) Management of Varirations in Blood Pressure During Care of Organ Donors. Progress in Transplantation 10:25-32
55. Powner DJ, Kellum JA (2000) Maintaining Acid-Base Balance in Organ Donors. Transplantation 10:98-105
56. Randell TT, Höckerstedt KAV (1993) Triiodothyroine Treatment is Not Indicated in Braindead Multiorgan Donors: A Controlled Study. Transplant Proc 25:1552-1553
57. Rosendale JD, Kauffmann HM, McBride MA (2003) Aggressive pharmacologic donor management results in more tansplanted organs. Transplantation 75:482-487
58. Rosendale JD, Chabalewski FL, McBride MA, Garrity ER, Rosengard BR, Delmonico FL, Kauffmann HM (2002) Increased Transplanted Organs from the Use of a Standardized Donor Managment Protocol. Am J Transplant 2:761-768
59. Salim Ali, Vassiliu Patelis. (2001) The role of thyroid hormone administration in potential organ donors. Arch Surg 136:1372-1380
60. Sebening C, Hagl C, Szabo G et al (1995) Cardiocirculatory Effects of Acutely Increased Intracranial Pressure and Subsequent Brain Death. Eur J Cardiothorac Sur 9:360-372
61. Shumway SJ, Hertz MI, Patty MG, Bolman RM III (1994) Liberalization of Donor Criteria in Lung and Heart-Lung Transplantation. Am. Thoracic Surgery 57:92-95
62. Sielenkämper A, Bone H-G, Booke M (2001) Anämie, Bluttransfusion und Gewebeoxygenation. Anästhesiologie & Intensivmedizin 42:304-313
63. Spiss CK (1997) Managment of the Multi-Organ Donor. ACTA Anaesthesiologica Scandinavica 111:77
64. Spiss CK, Metnitz PH, Schäfer B, Steltzer H (1995) Recent advances in transplantation anesthesia and intensive care medicine. Transplant Proc 27:2532-2537
65. Stoica SC, Satchithananda DK (2002) Swan-Ganz catheter assessment of donor hearts: outcome of organs with borderline hemodynamics. J Heart Lung Transplant 21:615-622
66. Straznicka M, Pollete DM, Eisner MD (2002) Aggressive management of lung donors classified as unacceptable: Excellent recipient survival one year after transplantation. Thorac Cardiovasc Surg 124:250-258
67. Timek T, Bonz A, Dillmann R, Vahl U (1998) The Effect of Triiodothyronine on Myocardial Contractile Performance after Epinephrine Exposure. J Heart Lung Transplantation 17:931-939
68. Timek T, Bonz A (1998) The Effect of Triiodothyroine on Myocardial Contractile Performance After Epinephrine Exposure: Implications for Donor Heart Management. J Heart Lung Transplant 17:931-940
69. Toda R, Kawai A, Moriyama Y, Taira A, Ferraro P, Griffith BP (1999) Evaluation and Procurement of Donor Heart and Lung in Multiple Organ Harvesting. Transplant Proc 31:2006-2011
70. Van den Berghe G, Wouters P et al (2001) Intensive insulin therapy in the critically ill patients. N Engl J Med 345:1359-1367
71. Weill D (2002) Donor Criteria in Lung Transplantation. Chest 121: 2029-2031
72. Weiss SJ, Muniz A, Ernst AA, Lippton HL, Nick TG (2000) The effect of prior hypothermia on the physiological response to norepinephrine. Resuscitation 45:201-207
73. Yoshioka T, Sugimoto H, Uenishi M, Sakamoto T, Sadamitsu D (1986) Prolonged Hemodynamic Maintenance by the Combined Administration of Vasopressin and Epinephrine in Brain Death: A Clinical Sudy. Neurosurgery 18:565-567
74. Wesslau C, Eferer K, Krüger R et al (1998) Untersuchungen von ausgewählten hämodynamischen, endokrinologischen und Entzündungsparametern beim Organspender und deren mögliche Beeinflussung durch die Gabe von Methylprednisolon. Transplantationsmedizin (suppl) 1998; 130
75. Zaroff JG, Rosengard BR (2002) Consensus conference report: maximising use of organs recovered from the cadaver donor. Circulation 106:836-841