Association of Morphological Characteristics with Precocious Puberty and/ or Gelastic Seizures in Hypothalamic Hamartoma

Journal of Clinical Endocrinology and Metabolism

Volumn 88, Issue 10, 2003, Pages 4590-4595

  Jung, H ^a,b   Probst, E Neumaier ^c   Hauffa, B P ^d   Partsch, C J ^e   Dammann, O ^f  

^a LILLY DEUTSCHLAND GMBH   (Germany)

^b UNIVERSITY HOSPITAL GIESSEN   (Germany)

^c UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^d UNIVERSITY HOSPITAL ESSEN   (Germany)

^e UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^f HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHILD; CLINICAL ARTICLE; CLINICAL EXAMINATION; COMPUTER ASSISTED TOMOGRAPHY; DISEASE ASSOCIATION; FEMALE; GELASTIC SEIZURE; HAMARTOMA; HUMAN; HYPOTHALAMUS DISEASE; HYPOTHALAMUS HAMARTOMA; LOGISTIC REGRESSION ANALYSIS; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRECOCIOUS PUBERTY; PRIORITY JOURNAL; RISK ASSESSMENT; SEX DIFFERENCE; TISSUE DISTRIBUTION;

BODY HEIGHT; CHILD; CHILD, PRESCHOOL; EPILEPSY, COMPLEX PARTIAL; ESTROGENS; FEMALE; GONADOTROPINS; HAMARTOMA; HUMANS; HYPOTHALAMIC DISEASES; INFANT; LOGISTIC MODELS; MAGNETIC RESONANCE IMAGING; MALE; PUBERTY, PRECOCIOUS; RETROSPECTIVE STUDIES; RISK FACTORS; SEX DISTRIBUTION; TESTOSTERONE; TOMOGRAPHY, X-RAY COMPUTED;

EID: 0242351856     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2002-022018     Document Type: Article

References (43)

1. Lichtenstein BW 1971 Hamartomas and phacomatoses. In: Minckler J, ed. Pathology of the nervous system. New York: McGraw-Hill; 1897-1906
2. Bedwell SF, Lindenberg R 1961 A hypothalamic hamartoma with dendritic proliferation and other neuronal changes associated with blastomatoid reaction of astrocytes. J Neuropathol Exp Neurol 20:219-239
3. Zuniga OF, Tanner SM, Wild WO, Mosier Jr HD 1983 Hamartoma of CNS associated with precocious puberty. Am J Dis Child 137:127-133
4. Richter RB 1950 True hamartoma of the hypothalamus associated with pubertas praecox. J Neuropathol Exp Neurol 10:368-383
5. Starceski PJ, Lee PA, Albright AL, Migeon CJ 1990 Hypothalamic hamartomas and sexual precocity. Evaluation of treatment options. Am J Dis Child 144:225-228
6. Mahachoklertwattana P, Kaplan SL, Grumbach MM 1993 The luteinizing hormone-releasing hormone-secreting hypothalamic hamartoma is a congenital malformation: natural history. J Clin Endocrinol Metab 77:118-124
7. Berkovic SF, Andermann F, Melanson D, Ethier RE, Feindel W, Gloor P 1988 Hypothalamic hamartomas and ictal laughter: evolution of a characteristic epileptic syndrome and diagnostic value of magnetic resonance imaging. Ann Neurol 23:429-439
8. Berkovic SF, Kuzniecky RI, Andermann F 1997 Human epileptogenesis and hypothalamic hamartomas: new lessons from experiment of nature. Epilepsia 38:1-3
9. Valdueza JM, Cristante L, Dammann O, Bentele K, Vortmeyer A, Saeger W, Padberg B, Freitag J, Herrmann HD 1994 Hypothalamic hamartomas: with special reference to gelastic epilepsy and surgery. Neurosurgery 34:949-958
10. Price RA, Lee PA, Albright AL, Ronnekleiv OK, Gutai JP 1984 Treatment of sexual precocity by removal of a luteinizing hormone-releasing hormone secreting hamartoma. JAMA 251:2247-2249
11. Jung H, Carmel P, Schwartz MS, Witkin JW, Bentele KHP, Westphal M, Piatt JH, Costa ME, Cornea A, Ma YJ, Ojeda SR 1999 Some hypothalamic hamartomas contain transforming growth factor α, a puberty-inducing growth factor, but not luteinizing hormone-releasing hormone neurons. J Clin Endocrinol Metab 84:4695-4701
12. Ma YJ, Junier MP, Costa ME, Ojeda SR 1992 Transforming growth factor-α gene expression in the hypothalamus is developmentally regulated and linked to sexual maturation. Neuron 9:657-670
13. Ojeda SR 1994 The neurobiology of mammalian puberty: has the contribution of glial cells been underestimated? J NIH Res 6:51-56
14. Junier MP, Ma YJ, Costa ME, Hoffman G, Hill DF, Ojeda SR 1991 Transforming growth factor a contributes to the mechanism by which hypothalamic injury induces precocious puberty. Proc Natl Acad Sci USA 88:9743-9747
15. Ojeda SR, Ma YJ 1995 Transforming growth factor α as a physiological regulator of female puberty: neuroendocrine and molecular studies. Front Endocrinol 10:173-182
16. Rage F, Hill DF, Sena-Esteves M, Breakfield XO, Coffey RJ, Costa ME, McCann SM, Ojeda SR 1997 Targeting transforming growth factor α expression to discrete loci of the neuroendocrine brain induces female sexual precocity. Proc Natl Acad Sci USA 94:2735-2740
17. Marshall WA, Tanner JM 1969 Variations in pattern of pubertal changes in girls. Arch Dis Child 44:291-303
18. Marshall WA, Tanner JM 1970 Variations in the pattern of pubertal changes in boys. Arch Dis Child 45:13-23
19. Largo RH, Prader A 1983 Pubertal development in Swiss boys. Helv Paediatr Acta 38:211-228
20. Zachmann M, Prader A, Kind HP, Haflinger H, Budlinger H 1974 Testicular volume during adolescence: cross-sectional and longitudinal studies. Helv Paediatr Acta 29:61-72
21. Reinken L, van Oost G 1992 [Longitudinal physical development of healthy children 0 to 18 years of age. Body length/height, body weight and growth velocity]. Klin Padiatr 204:129-133
22. Arita K, Ikawa F, Kurisu K, Sumida M, Harada K, Uozumi T, Monden S, Yoshida J, Nishi Y 1999 The relationship between magnetic resonance imaging findings and clinical manifestations of hypothalamic hamartoma. J Neurosurg 91:212-220
23. Cassio A, Cacciari E, Zucchini S, Balsamo A, Diegoli M, Orsini F 2000 Central precocious puberty: clinical and imaging aspects. J Pediatr Endocrinol Metab 13(Suppl 1):703-708
24. Debeneix C, Bourgeois M, Trivin C, Sainte-Rose C, Brauner R 2001 Hypothalamic hamartoma: comparison of clinical presentation and magnetic resonance images. Horm Res 56:12-18
25. Pescovitz OH, Comite F, Hench K, Barnes K, McNemar A, Foster C, Kenigsberg D, Loriaux DL, Cutler Jr GB 1986 The NIH experience with precocious puberty: diagnostic subgroups and response to short-term luteinizing hormone releasing hormone analogue therapy. J Pediatr 108:47-54
26. Brauner R, Thibaud E, Pomarede R, Cachin O, Hausser C, Czernichow P, Rappaport R 1982 [Precocious puberty. Comment on the diagnostic conditions and etiological aspects]. Ann Endocrinol (Paris) 43:497-508
27. Kornreich L, Horev G, Blaser S, Daneman D, Kauli R, Grunebaum M 1995 Central precocious puberty: evaluation by neuroimaging. Pediatr Radiol 25:7-11
28. Desai M, Colaco MP, Choksi CS, Ambadkar MC, Vaz FE, Gupte C 1993 Isosexual precocity: the clinical and etiologic profile. Indian Pediatr 30:607-623
29. Feuillan PP, Jones JV, Barnes K, Oerter-Klein K, Cutler Jr GB 1999 Reproductive axis after discontinuation of gonadotropin-releasing hormone analog treatment of girls with precocious puberty: long term follow-up comparing girls with hypothalamic hamartoma to those with idiopathic precocious puberty. J Clin Endocrinol Metab 84:44-49
30. Sturm JW, Andermann F, Berkovic SF 2000 "Pressure to laugh": an unusual epileptic symptom associated with small hypothalamic hamartomas. Neurology 54:971-973
31. Commentz JC, Helmke K 1995 Precocious puberty and decreased melatonin secretion due to a hypothalamic hamartoma. Horm Res 44:271-275
32. Alvarez-Garijo JA, Albiach VJ, Vila MM, Mulas F, Esquembre V 1983 Precocious puberty and hypothalamic hamartoma with total recovery after surgical treatment. Case report. J Neurosurg 58:583-585
33. Munari C, Kahane P, Francione S, Hoffmann D, Tassi L, Cusma R, Vigevano F, Pasquier B, Betti OO 1995 Role of the hypothalamic hamartoma in the genesis of gelastic fits (a video-stereo-EEG study). Electroencephalogr Clin Neurophysiol 95:154-160
34. Breningstall GN 1985 Gelastic seizures, precocious puberty, and hypothalamic hamartoma. Neurology 35:1180-1183
35. Kahane P, Di Leo M, Hoffmann D, Munari C 1999 Ictal bradycardia in a patient with a hypothalamic hamartoma: a stereo-EEG study. Epilepsia 40:522-527
36. Simerly RB 2002 Wired for reproduction: organization and development of sexually dimorphic circuits in the mammalian forebrain. Annu Rev Neurosci 25:507-536
37. Henderson RG, Brown AE, Tobet SA 1999 Sex differences in cell migration in the preoptic area/anterior hypothalamus of mice. J Neurobiol 41:252-266
38. Mong JA, Roberts RC, Kelly JJ, McCarthy MM 2001 Gonadal steroids reduce the density of axospinous synapses in the developing rat arcuate nucleus: an electron microscopy analysis. J Comp Neurol 432:259-267
39. Chatelain P, Morel Y 1996 Ovarian function. In: Ranke MB, ed. Diagnostics of endocrine function in children and adolescents. Heidelberg, Leipzig: Johann Ambrosius Barth Verlag; 326-345
40. Partsch C-J, Hümmelink R, Sippell WG 1990 Reference ranges for lutropin and follitropin in the luliberin test in prepubertal and pubertal children using a monoclonal immunoradiometric assay. J Clin Chem Clin Biochem 28:49-52
41. Pescovitz OH, Hench KD, Barnes KM, Loriaux DL, Cutler Jr GB 1988 Premature thelarche and central precocious puberty: the relationship between clinical presentation and the gonadotropin response to luteinizing hormone-releasing hormone. J Clin Endocrinol Metab 67:474-479
42. Partsch C-J, Hümelink R, Lorenzen F, Sippell WG 1989 The significance of the LHRH test in the diagnosis of premature sexual development in girls: the stimulated LH/FSH ratio differentiates between central precocious puberty and premature thelarche. Monatsschr Kinderheilkd 137:284-288
43. Honour JW, Savage MO 1996 Testicular endocrine function. In: Ranke MB, ed. Diagnostics of endocrine function in children and adolescents. Heidelberg, Leipzig: Johann Ambrosius Barth Verlag; 314-325