Cylindrospermopsin occurrence in two German lakes and preliminary assessment of toxicity and toxin production of Cylindrospermopsis raciborskii (Cyanobacteria) isolates

Toxicon

Volumn 42, Issue 3, 2003, Pages 313-321

  Fastner, J ^a   Heinze, R ^a   Humpage, A R ^b   Mischke, U ^c   Eaglesham, G K ^d   Chorus, I ^a  

^a UMWELTBUNDESAMT   (Germany)

^b AUSTRALIAN WATER QUALITY CENTRE   (Australia)

^c BRANDENBURG UNIVERSITY OF TECHNOLOGY   (Germany)

^d QLD Health Scientific Services   (Australia)

Author keywords

Cyanobacteria; Cylindrospermopsin; Cylindrospermopsis raciborskii; Cytotoxicity; Toxicity

Indexed keywords

BACTERIAL TOXIN; CYLINDROSPERMOPSIN; DRINKING WATER; FRESH WATER; METHANOL; POISON;

ANIMAL CELL; ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; BIOASSAY; CELL ISOLATION; CELL LINE; CELL PROLIFERATION; CELL STRAIN CACO 2; CELL STRAIN HEPG2; CYANOBACTERIUM; CYLINDROSPERMOPSIS RACIBORSKII; ENTERITIS; GERMANY; HUMAN; HUMAN CELL; INFLAMMATION; INTESTINE; LAKE ECOSYSTEM; LIVER CELL; LIVER INJURY; MALE; MOUSE; NONHUMAN; POPULATION; PRIORITY JOURNAL; RECREATION; SHELLFISH; SPLEEN INJURY; TOXICITY TESTING;

CYANOBACTERIA; CYLINDROSPERMOPSIS RACIBORSKII;

EID: 0242349148     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(03)00150-8     Document Type: Article

References (48)

1. Banker R., Carmeli S., Hadas O., Teltsch B., Porat R., Sukenik A. Identification of cylindrospermopsin in the cyanobacterium Aphanizomenon ovalisporum (Cyanophyceae) isolated from lake Kinneret. Isr. J. Phycol. 33:1997;613-616.
2. Bernard C., Harvey M., Briand J.F., Bire R., Krys S., Fontaine J.J. Toxicological comparison of diverse Cylindrospermopsis raciborskii strains: evidence of liver damage caused by a French C. raciborskii strain. Environ. Toxicol. 18:2003;176-186.
3. Borenfreund E., Puerner J.A. Toxicity determination in vitro by morphological alterations and neutral red absorption. Toxicol. Lett. 24:1985;119-124.
4. Bourke A.T.C., Hawes R.B., Neilson A., Stallman N.D. An outbreak of the hepatoenteritis (the Palm island mystery disease) possibly caused by algal intoxication. Toxicon. (Suppl. 3):1983;45-48.
5. Bouvy M., Falcão D., Marinho M., Pagano M., Moura A. Occurrence of Cylindrospermopsis (Cyanobacteria) in 39 Brazilian tropical reservoirs during the 1998 drought. Aquat. Microb. Ecol. 23:2000;13-27.
6. Briand, J.F., Robillot, C., Quiblier-Lloberas, C., Kryss, S., Couté, A., Bernard, C., 2000. Cylindrospermopsis raciborskii blooms in a shallow pond in France: dynamic factors and preliminary toxicity studies. Eurocyan Workshop: Europe facing toxic cyanobacterial blooms, Toulouse 12-14 December (2000), Book of abstracts.
7. Chapman A.D., Schelske C.L. Recent appearance of Cylindrospermopsis (cyanobacteria) in five hypertrophic Florida lakes. J. Phycol. 33:1997;191-195.
8. Chong M.W.K., Wong B.S.F., Lam P.K.S., Shaw G.R., Seawright A.A. Toxicity and uptake mechanism of cylindrospermopsin and lophyrotomin in primary rat hepatocytes. Toxicon. 40:2002;205-211.
9. Dokulil M.T., Mayer J. Population dynamics and photosynthetic rates of a Cylindrospermopsis-Limnothrix association in a highly eutrophic urban lake, Alte Donau, Vienna, Austria. Algol. Studies. 83:1996;179-195.
10. Eaglesham G.K., Norris R.L., Shaw G.R., Smith M.J., Chiswell R.K., Davis B.C., Neville G.R., Seawright A.A., Moore M.R. Use of HPLC-MS/MS to monitor cylindrospermopsin, a blue-green algal toxin, for public health purposes. Environ. Toxicol. 14:1999;151-154.
11. Falconer I.R., Humpage A.R. Preliminary evidence for in vivo tumour initiation by oral administration of extracts of the blue-green alga Cylindrospermopsis raciborskii containing the toxin cylindrospermopsin. Environ. Toxicol. 16:2001;192-195.
12. Falconer I.R., Jackson A.R.B., Langley J., Runnegar M.T.C. Liver pathology in mice in poisoning by the blue-green alga in Microcystis aeruginosa. Aust. J. Biol. Sci. 34:1981;179-187.
13. Falconer I.R., Hardy S.J., Humpage A.R., Froscio S.M., Tozer G.J., Hawkins P.R. Hepatic and renal toxicity of the blue-green alga (cyanobacterium) Cylindrospermopsis raciborskii in male Swiss Albino mice. Environ. Toxicol. 14:1999;143-150.
14. Fergusson K.M., Saint C.P. Multiplex PCR assay for Cylindrospermopsis raciborskii and cylindrospermopsin-producing cyanobacteria. Environ. Toxicol. 18:2003;120-125.
15. Froscio S.M., Humpage A.R., Burcham P.C., Flaconer I.R. Cylindrospermopsin-induced protein synthesis inhibition and its dissociation from acute toxicity in mouse hepatocytes. Environ. Toxicol. 2003;. in press.
16. Harada K.-I., Ohtani I., Iwamoto K., Suzuki M., Watanabe M.F., Watanabe M., Terao K. Isolation of cylindrospermopsin from a cyanobacterium Umezakia natans and its screening method. Toxicon. 32:(1):1994;73-84.
17. Hawkins P.R., Runnegar M.T.C., Jackson A.R.B., Falconer I.R. Severe hepatotoxicity caused by the tropical cyanobacterium (blue-green alga) Cylindrospermopsis raciborskii (Woloszynska) Seenayya et Subba Raju isolated from a domestic water supply reservoir. Appl. Environ. Microbiol. 50:1985;1292-1295.
18. Hawkins P.R., Chandrasena N.R., Jones G.J., Humpage A.R., Falconer I.R. Isolation and toxicity of Cylindrospermopsis raciborskii from an ornamental lake. Toxicon. 35:1997;341-346.
19. Heinze R. A biotest for hepatotoxins using primary rat hepatocytes. Phycologia. 35:(Supplement):1996;89-93.
20. Humpage A.R., Fenech M., Thomas P., Falconer I.R. Micronucleus induction and chromosome loss in transformed human white cells indicate clastogenic and aneugenic action of the cyanobacterial toxin, cylindrospermopsin. Mutat. Res. 472:2000;155-161.
21. Krienitz L., Hegewald E. Über das Vorkommen von wärmeliebenden Blaualgenarten in einem norddeutschen Gewässer. Lauterbornia H. 26:1996;55-63. [in German].
22. Lagos N., Onodera H., Zagatto P.A., Andrinolo D., Azevedo S.M.F.Q., Oshima Y. The first evidence of paralytic shellfish toxins in the freshwater cyanobacterium Cylindrospermopsis raciborskii, isolated from Brazil. Toxicon. 37:1999;1359-1373.
23. Li R., Carmichael W.W., Brittain S., Eaglesham G.K., Shaw G.R., Noparatnaraporn A.M.N., Yongmanitchai W., Kaya K., Watanabe M.M. Detection of cylindrospermopsin from a strain of Cylindrospermopsis raciborskii (Cyanobacteria) isolated from Thailand. Toxicon. 39:2001;973-980.
24. Li R., Carmichael W.W., Brittain S., Eaglesham G.K., Shaw G.R., Yongding L., Watanabe M.M. First report of the cyanotoxins cylindrospermopsin and deoxycylindrospermopsin from Raphidiopsis curvata (cyanobacteria). J. Phycol. 37:2001;1121-1126.
25. McGregor G.B., Fabbro L.D. Dominance of Cylindrospermopsis raciborskii (Nostocales, Cyanoprokaryota) in Queensland tropical and subtropical reservoirs: implications for monitoring and management. Lakes Reservoirs: Res. Mgmt. 5:2000;195-205.
26. Metcalf J.S., Lindsay J., Beattie K.A., Birmingham S., Saker M.L., Torokne A.K., Codd G.A. Toxicity of cylindrospermopsin to the brine shrimp Artemia salina: comparisons with protein synthesis inhibitors and microcystins. Toxicon. 40:2002;1115-1120.
27. Mischke U. Cyanobacteria associations in shallow polytrophic lakes. Influence of environmental factors. Acta Oecol. 24:2003;11-23.
28. Mosman T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Meth. 65:1983;55-63.
29. Norris R.L., Eaglesham G.K., Pierens G., Shaw G.R., Smith M.J., Chiswell R.K., Seawright A.A., Moore M.R. Deoxycylindrospermopsin, an analog of cylindrospermopsin from Cylindrospermopsis raciborskii. Environ. Toxicol. 14:1999;163-166.
30. Norris R.L., Seawright A.A., Shaw G.R., Smith M.J., Chiswell R.K., Moore M.R. Distribution of 14C cylindrospermopsin in vivo in the mouse. Environ. Toxicol. 16:2001;498-505.
31. O'Brien T., Babcock G., Cornelius J., Dingeldein M., Talaska G., Warshawsky D., Mitchell K. A comparison of apoptosis and necrosis induced by hepatotoxins in HEP-G2 cells. Toxicol. Appl. Pharmacol. 164:2000;280-290.
32. Ohtani I., Moore R.E., Runnegar M.T.C. Cylindrospermopsin: A potent hepatotoxin from the blue-green alga Cylindrospermopsis raciborskii. J. Am. Chem. Soc. 114:1992;7941-7942.
33. Padisák J. Cylindrospermopsis raciborskii (Woloszynska) Seenayya et Subba Raju, an expanding highly adaptive blue-green algal species: worldwide distribution and review of its ecology. Arch. Hydrobiol. Suppl. 107:1997;563-593.
34. Rücker J., Wiedner C., Zippel P. Factors controlling the dominance of Planktothrix agardhii and Limnothrix redekei in eutrophic shallow lakes. Hydrobiologia. 342/343:1997;107-115.
35. Runnegar M.T., Kong S.M., Zhong Y.Z., Lu S.C. Inhibition of reduced glutathione synthesis by cyanobacterial alkaloid cylindrospermopsin in cultured rat hepatocytes. Biochem. Pharmacol. 49:1995;219-225.
36. Saker M.L., Eaglesham G.K. The accumulation of cylindrospermopsin from the cyanobacterium Cylindrospermopsis raciborskii in tissues of the Redclaw crayfish Cherax quadricarinatus. Toxicon. 37:1999;1065-1077.
37. Saker M.L., Griffiths D.J. The effect of temperature on growth and cylindrospermopsin content of seven isolates of Cylindrospermopsis raciborskii (Nostocales, Cyanophyceae) from water bodies in northern Australia. Phycologia. 39:2000;349-354.
38. Saker M.L., Nogueira I.C.G., Vasconcelos V.M., Neilan B.A., Eaglesham G.K., Pereira P. First report and toxicological assessment of the cyanobacterium Cylindrospermopsis raciborskii from Portuguese freshwaters. Ecotoxicol. Environ. Saf. 55:2003;243-250.
39. Schembri M.A., Neilan B.A., Saint C.P. Identification of genes implicated in toxin production in the cyanobacterium Cylindrospermopsis raciborskii. Environ. Toxicol. 16:2001;413-421.
40. Seawright A.A., Nolan C.C., Shaw G.R., Chiswell R.K., Norris R.L., Moore M.R., Smith M.J. The oral toxicity for mice of the tropical cyanobacterium Cylindrospermopsis raciborskii (Woloszynska). Environ. Toxicol. 14:1999;135-142.
41. Seglen P.O. Preparation of isolated rat liver cells. Meth. Cell Biol. 13:1976;29-83.
42. Sivonen K., Jones G.J. Cyanobacterial toxins. Chorus I., Bartram J. A Guide to Their Public Health Consequences, Monitoring and Management. A Guide to Their Public Health Consequences, Monitoring and Management. 1999;41-111 E and FN Spon, London.
43. Tallkvist J., Tjälve H. Transport of nickel across monolayers of human intestinal CACO-2 cells. Toxicol. Appl. Pharmacol. 151:1998;117-122.
44. Terao K., Ohmori S., Igarashi K., Ohtani I., Watanabe M.F., Harada K.I., Ito E., Watanabe M. Electron microscopic studies on experimental poisoning in mice induced by cylindrospermopsin isolated from blue-green alga Umezakia natans. Toxicon. 32:1994;833-843.
45. Török-Kozma A., Mayer G. Toxicus cianobaktériumok hazai felszíni vizeinkben (Toxic cyanobacteria in Hungarian Freshwaters). Hidrológiai Közlöny. 68:1988;49-54. [in Hungarian with English summary].
46. Welker M., Bickel H., Fastner J. HPLC-PDA detection of cylindrospermopsin - opportunities and limits. Water Res. 36:2002;4659-4663.
47. Wiedner C., Nixdorf B., Heinze R., Wirsing B., Neumann U., Weckesser J. Regulation of cyanobacteria and microcystin dynamics in polymictic shallow lakes. Arch. Hydrobiol. 155:2002;383-400.
48. Zehnder A., Gorham P.R. Factors influencing the growth of Microcystis aeruginosa Kütz. emend. Elenkin. Can. J. Microbiol. 6:1960;645-660.