Using high spectral and spatial resolution bold MRI to choose the optimal oxygenating treatment for individual cancer patients

Advances in Experimental Medicine and Biology

Volumn 530, Issue , 2003, Pages 433-440

  Al Hallaq, Hania A ^a   Zamora, Marta A ^a   Fish, Brian L ^b   Halpern, Howard J ^a   Moulder, John E ^b   Karczmar, Gregory S ^a,b  

^a UNIVERSITY OF CHICAGO   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Magnetic resonance imaging; Oxygen blood; Radiation sensitizing agents; Rats

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; CONFERENCE PAPER; CONTROLLED STUDY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OPTICAL RESOLUTION; OXYGEN TISSUE LEVEL; PRIORITY JOURNAL; RADIOSENSITIVITY; RAT; RHABDOMYOSARCOMA; TISSUE OXYGENATION; TUMOR BLOOD FLOW;

ANIMALIA;

EID: 0242330632     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-0075-9_40     Document Type: Conference Paper

References (14)

1. Thomlinson RH, Gray LH. The histological structure of some human lung cancers and the possible implications for radiotherapy. Br J Cancer 1955;9:539-549.
2. Horsman MR. Nicotinamide and other benzamide analogs as agents for overcoming hypoxic cell radiation resistance in tumours. A review. Acta Oncol 1995;34:571-587.
3. Rojas A. Radiosensitization with normobaric oxygen and carbogen. Radiother Oncol 1991;20(Suppl 1):65-70.
4. Martin DF, Porter EA, Fischer JJ, Rockwell S. Effect of a perfluorochemical emulsion on the radiation response of BA1112 rhabdomyosarcomas. Radiat Res 1987;112:45-53.
5. Saunders M, Dische S. Clinical results of hypoxic cell radiosensitisation from hyperbaric oxygen to accelerated radiotherapy, carbogen and nicotinamide. Br J Cancer 1996;74(Suppl 27):S271-278.
6. Ogawa S, Lee TM. Magnetic resonance imaging of blood vessels at high fields: in vivo and in vitro measurements and image simulation. Magn Reson Med 1990;16:9-18.
7. Rockwell S, Kelley M, Irvin CG, Hughes CS, Porter E, Yabuki H, et al. Modulation of tumor oxygenation and radiosensitivity by a perfluorooctylbromide emulsion. Radiother Oncol 1991;22:92-98.
8. Brown TR, Kincaid BM, Ugurbil K. NMR chemical shift imaging in three dimensions. Proc Natl Acad Sci U S A 1982;79:3523-3526.
9. Oikawa H, Al-Hallaq HA, Lewis MZ, River JN, Kovar DA, Karczmar GS. Spectroscopic imaging of the water resonance with short repetition time to study tumor response to hyperoxia. Magn Reson Med 1997;38:27-32.
10. Al-Hallaq HA, River JN, Zamora M, Oikawa H, Karczmar GS. Correlation of magnetic resonance and oxygen microelectrode measurements of carbogen-induced changes in tumor oxygenation. Int J Radiat Oncol Biol Phys 1998;41:151-159.
11. Zar JH. Biostatistical Analysis. Englewood Cliffs (NJ): Prentice-Hall, Inc.; 1974.
12. Rofstad EK, Fenton BM, Sutherland RM. Intracapillary HbO2 saturations in murine tumours and human tumour xenografts measured by cryospectrophotometry: relationship to tumour volume, tumour pH and fraction of radiobiologically hypoxic cells. Br J Cancer 1988;57:494-502.
13. Robinson SP, Howe FA, Griffiths JR. Noninvasive monitoring of carbogen-induced changes in tumor blood flow and oxygenation by functional magnetic resonance imaging. Int J Radiat Oncol Biol Phys 1995;33:855-859.
14. Kovar DA, Al-Hallaq HA, Zamora MA, River JN, Karczmar GS. Fast spectroscopic imaging of water and fat resonances to improve the quality of MR images. Acad Radiol 1998;5:269-275.