Splanchnic and extrasplanchnic extraction of insulin following oral and intravenous glucose loads

Clinical Science

Volumn 97, Issue 4, 1999, Pages 429-436

  Brundin, Tomas ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

C peptide; Gastric inhibiting polypeptide; Glucagon like peptide; Incretin mechanism; Insulin secretion; Intestinal hormones; Postprandial insulinaemia; Splanchnic blood flow

Indexed keywords

C PEPTIDE; INSULIN;

ADULT; ARTICLE; BLOOD LEVEL; CATHETERIZATION; CLINICAL ARTICLE; CONTROLLED STUDY; ENERGY EXPENDITURE; GLUCOSE TOLERANCE TEST; HUMAN; HUMAN EXPERIMENT; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULINEMIA; LUNG GAS EXCHANGE; MALE; NORMAL HUMAN; OXYGEN CONSUMPTION; PANCREAS; POSTPRANDIAL STATE; PRIORITY JOURNAL; SPLANCHNIC BLOOD FLOW;

ADMINISTRATION, ORAL; ADULT; BLOOD GLUCOSE; C-PEPTIDE; ENERGY METABOLISM; GLUCOSE; HEART RATE; HEMOGLOBINS; HUMANS; INFUSIONS, INTRAVENOUS; INSULIN; MALE; OXYGEN CONSUMPTION; PULMONARY GAS EXCHANGE; SPLANCHNIC CIRCULATION;

EID: 0032825081     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS19990023     Document Type: Article

References (21)

1. 1 Waldhäusl, W., Bratusch-Marrain, P., Gasic, S., Korn, A. and Nowotny, P. (1979) Insulin production rate following glucose ingestion estimated by splanchnic C-peptide output in normal man. Diabetologia 17, 221-227
2. 2 Brundin, T. (1998) Whole body and splanchnic metabolic, circulatory, and thermal effects of oral vs. intravenous fat administration. Am. J. Physiol. 274, K684-E691
3. 3 Schuster, L. T., Go, W. L. W., Rizza, R. A., O'Brien, P. C. and Service, J. (1988) Incretin effect due to increased secretion and decreased clearance of insulin in normal humans. Diabetes 37, 200-203
4. 4 Bradley, S. E., Ingelfinger, F. J., Bradley, G. P. and Curry, J. J. (1945) The estimation of hepatic blood flow in man. J. Clin. Invest. 24, 890-897
5. 5 Rowell, L. B., Blackmon, J. R. and Bruce, R. A. (1964) Indocyanine green clearance and estimated hepatic blood flow during mild to maximal exercise in upright man. J. Clin. Invest. 43, 1677-1690
6. 6 Burns, E., Ball, C. E., Christie, J. P., Broadhead, G. D., Tucker, G. T. and Bax, N. D. X. (1989) Direct and indirect measurement of the hepatic extraction ratio of indocyanine green in the rat. Clin. Sci. 76, 503-508
7. 7 Banauch, D., Brümmer, W., Ebeling, W. et al. (1975) Eine Glucose-Dehydrogenase für die Glucose-Bestimmung in Körperflüssigkeiten. Z. Klin. Chem. Klin. Biochem. 13, 101-107
8. 8 Herbert, V., Lau, K. S., Gottlieb, C. W. and Bleicher, S. J. (1965) Coated charcoal immunoassay of insulin. J. Clin. Endocrinol. Metab. 25, 1375-1384
9. 9 Heding, L. G. (1975) Radioimmunological determination of human C-peptide in serum. Diabetologia 11, 541-548
10. 10 Fick, A. (1870) Über die Messung des Blutquantums in den Herzventrikeln. In Sitzungsberichte der phys-med Ges zu Würzburg, XIV. Sitzung am 9. Juli, p. 16
11. 11 Sjöstrand, T. (1967) The blood. In Clinical Physiology: Pathophysiological Basis and Practical Application (Sjöstrand, T., ed.), pp. 3-14, Svenska Bokfürlaget, Stockholm
12. 12 Harris, J. A. and Benedict, F. G. (1919) A biometric study of basal metabolism in man. Carnegie Inst. Washington. Publ. 279, 1-266
13. 13 Elrick, H., Stimmler, L., Hlad, C. J. and Arai, Y. (1964) Plasma insulin responses to oral and intravenous glucose administration. J. Clin. Endocrinol. Metab. 24, 1076-1082
14. 14 Perley, M. J. and Kipnis, D. M. (1967) Plasma insulin responses to oral and intravenous glucose: studies in normal and diabetic subjects. J. Clin. Invest. 46, 1954-1962
15. 15 Dupé, J. (1964) An intestinal hormone affecting glucose disposal in man. Lancet ii, 672-673
16. 16 McIntyre, N., Holdsworth, C. D. and Turner, D. S. (1964) New interpretation of oral glucose tolerance. Lancet ii, 20-21
17. 17 Creutzfeld, W. (1979) The incretin concept today. Diabetologia 16, 75-85
18. 18 Brundin, T. and Wahren, J. (1993) Whole-body and splanchnic oxygen consumption and blood flow after oral ingestion of fructose or glucose. Am. J. Physiol. 264, E504-E513
19. 19 Brundin, T., Bränström, R. and Wahren, J. (1996) Effects of oral vs i.v. glucose administration on splanchnic and extra-splanchnic oxygen uptake and blood flow. Am. J. Physiol. 271, E496-E504
20. 20 Brundin, T., Aksnes, A.-K. and Wahren, J. (1997) Whole body and splanchnic metabolic and circulatory effects of glucose during β-adrenergic receptor inhibition. Am. J. Physiol. 272, E678-E687
21. 21 Rasio, E. (1970) Vascular endothelium; a site for insulin diffusion, adsorption and release. Panminerva Med. 12, 236-238