Using Front-end Kinetics to Optimize Target-controlled Drug Infusions

Anesthesiology

Volumn 99, Issue 5, 2003, Pages 1078-1086

  Avram, Michael J ^a   Krejcie, Tom C ^b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

THIOPENTAL;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; COMPARTMENT MODEL; DOG; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG DISTRIBUTION VOLUME; DRUG INFUSION; FRONT END KINETICS; MALE; NONHUMAN; PHARMACOKINETICS; PREDICTION; PRIORITY JOURNAL; PROCESS OPTIMIZATION; RECIRCULATORY MODEL; SIMULATION; TARGET CONTROLLED DRUG INFUSION; THREE COMPARTMENT MODEL;

ANESTHETICS, INTRAVENOUS; ANIMALS; COLORING AGENTS; DOGS; INDOCYANINE GREEN; INFUSIONS, INTRAVENOUS; MALE; MODELS, BIOLOGICAL; PHARMACOKINETICS; THIOPENTAL;

EID: 0242300739     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-200311000-00013     Document Type: Article

References (33)

1. Krejcie TC, Avram MJ: What determines the anesthetic induction dose? It's the front-end kinetics, Doctor! Anesth Analg 1999; 89:541-4
2. Atkinson AJ Jr, Ruo TI, Frederiksen MC: Physiological basis of multicompartmental models of drug distribution. Trends Pharmacol Sci 1991; 12:96-101
3. Niazi S: Volume of distribution as a function of time. J Pharm Sci 1976; 65:452-4
4. Colburn WE: A time-dependent volume of distribution term used to describe linear concentration-time profiles. J Pharmacokinet Biopharm 1983; 11: 389-400
5. Avram MJ, Henthorn TK, Shanks CA, Krejcie TC: The initial rate of change in distribution volume is the sum of intercompartmental clearances. J Pharm Sci 1986; 75:919-20
6. Chiou WL: Potential effect of early blood sampling schedule on calculated pharmacokinetic parameters of drugs after intravenous administration. J Pharm Sci 1980; 69:867-9
7. Weiss M: Modelling of initial distribution of drugs following intravenous bolus injection. Eur J Clin Pharmacol 1983; 24:121-6
8. Chiou WL: Potential pitfalls in the conventional pharmacokinetic studies: Effects of the initial mixing of drug in blood and the pulmonary first-pass elimination. J Pharmacokinet Biopharm 1979; 7:527-36
9. Wada DR, Drover DR, Lemmens HJM: Determination of the distribution volume that can be used to calculate the intravenous loading dose. Clin Pharmacokinet 1998; 35:1-7
10. Henthorn TK, Avram MJ, Krejcie TC, Shanks CA, Asada A, Kaczynski DA: Minimal compartmental model of circulatory mixing of indocyanine green. Am J Physiol 1992; 262:H903-10
11. Krejcie TC, Henthorn TK, Niemann CU, Kleín C, Gupta DK, Gentry WB, Shanks CA, Avram MJ: Recirculatory pharmacokinetic models of blood, extracellular fluid and total body water administered concomitantly. J Pharmacol Exp Ther 1996; 278:1050-7
12. Avram MJ, Krejcie TC, Niemann CU, Klein C, Gentry WB, Shanks CA, Henthorn TK: The effect of halothane on the recirculatory pharmacokinetics of physiologic markers. ANESTHESIOLOGY 1997; 87:1381-93
13. Chiou WL: The phenomenon and rationale of marked dependence of drug concentration on blood sampling site: Implications in pharmacokinetics, toxicology and therapeutics: I. Clin Pharmacokinet 1989; 17:175-99
14. Chiou WL: The phenomenon and rationale of marked dependence of drug concentration on blood sampling site: Implications in pharmacokinetics, toxicology and therapeutics: II. Clin Pharmacokinet 1989; 17:275-90
15. Krejcie TC, Jacquez JA, Avram MJ, Niemann CU, Shanks CA, Henthorn TK: Use of parallel Erlang density functions to analyze first-pass pulmonary uptake of multiple indicators in dogs. J Phamacokin Biopharm 1996; 24:569-88
16. Krejcie TC, Avram MJ, Gentry WB, Niemann CU, Jankowski MP, Henthorn TK: A recirculatory model of the pulmonary uptake and pharmacokinetics of lidocaine based on analysis of arterial and mixed venous data from dogs. J Phamacokin Biopharm 1997; 25:169-90
17. Avram MJ, Krejcie TC, Henthorn TK: The concordance of early antipyrine and thiopental distribution kinetics. J Pharmacol Exp Ther 2002; 302:594-600
18. Garner D, Laks MM: New implanted chronic catheter device for determining blood pressure and cardiac output in conscious dogs. Am J Physiol 1985; 249:H861-4
19. Grasela DM, Rocci ML Jr, Vlasses PH: Experimental impact of assay-dependent differences in plasma indocyanine green concentration determinations. J Pharmacokinet Biopharm 1987; 15:601-13
20. Avram MJ, Krejcie TC: Determination of sodium pentobarbital and either sodium methohexital or sodium thiopental in plasma by high performance liquid chromatography with ultraviolet detection. J Chromatogr 1987; 414:484-91
21. Jacquez, JA: Compartmental Analysis in Biology and Medicine, 3rd edition. Ann Arbor, BioMedware, 1996
22. Foster DM: Developing and testing integrated multicompartment models to describe a single-input multiple-output study using the SAAM II software system. Adv Exp Med Biol 1998; 445:59-78
23. Krejcie TC, Henthorn TK, Shanks CA, Avram MJ: A recirculatory pharmacokinetic model describing the circulatory mixing, tissue distribution and elimination of antipyrine in dogs. J Pharmacol Exp Ther 1994; 269:609-16
24. Schwilden H, Schüttler J, Stoekel H: Pharmacokinetics as applied to total intravenous anesthesia: Theoretical considerations. Anaesthesia 1983; 38(suppl): 51-2
25. Wada DR, Ward DS: The hybrid model: A new pharmacokinetic model for computer-controlled infusion pumps. IEE Trans Biomed Eng 1994; 41: 134-42
26. Schüttler J, Ihmsen H: Population pharmacokinetics of propofol: A multicenter study. ANESTHESIOLOGY 2000; 92:727-38
27. Van den Nieuwenhuyzen MC, Engbers FH, Vuyk J, Burm AG: Target-controlled infusion systems: Role in anaesthesia and analgesia. Clin Pharmacokinet 2000; 38:181-90
28. Raemer DB, Buschman A, Varvel JR, Philip BK, Johnson MD, Stein DA, Shafer SL: The prospective use of population pharmacokinetics in a computer-driven infusion system for alfentanil. ANESTHESIOLOGY 1990; 73:66-72
29. Barvais L, Canraine F, D'Hollander A, Coussaert E: Predictive accuracy of continuous alfentanil infusion in volunteers: Variability of different pharmacokinetic sets. Anesth Analg 1993; 77:801-10
30. Shafer SL, Varvel JR, Aziz N, Scott JC: Pharmacokinetics of fentanyl administered by computer-controlled infusion pump. ANESTHESIOLOGY 1990; 1091-1102
31. Schnider TW, Gaeta R, Brose W, Minto CF, Gregg KM, Shafer SL: Derivation and cross-validation of pharmacokinetic parameters for computer-controlled infusion of lidocaine in pain therapy. ANESTHESIOLOGY 1996; 84:1043-50
32. Vuyk J, Engbers FHM, Burm AGL, Vletter AA, Bovill JG: Performance of computer-controlled infusion of propofol: An evaluation of five pharmacokinetic parameter sets. Anesth Analg 1995; 81:1275-82
33. Schnider TW, Minto CF, Gambus PL, Andresen C, Goodale DB, Shafer SL, Youngs EJ: The influence of method of administration on the pharmacokinetics of propofol in adult volunteers. ANESTHESIOLOGY 1998; 88:1170-82