Dissecting the associations of endemic pemphigus foliaceus (fogo selvagem) with HLA-DRB1 alleles and genotypes

Genes and Immunity

Volumn 4, Issue 2, 2003, Pages 110-116

  Pavoni, D P ^a   Roxo, V M M S ^a   Marquart Filho, A ^b   Petzl Erler, M L ^b  

^a FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^b Hospital Adventista do Penfigo   (Brazil)

Author keywords

Brazilian population; Genetic association; Genetic susceptibility; HLA DRB; MHC; Pemphigus

Indexed keywords

AMINO ACID; AUTOANTIBODY; DESMOGLEIN 1; HLA DR ANTIGEN; HLA-DRB1 ANTIGEN;

ALLELE; ARTICLE; AUTOIMMUNE DISEASE; BRAZIL; BULLOUS SKIN DISEASE; CONTROLLED STUDY; ENVIRONMENTAL FACTOR; ETHNOLOGY; GENE FREQUENCY; GENE INTERACTION; GENETIC ANALYSIS; GENOTYPE; HEREDITY; HUMAN; MAJOR CLINICAL STUDY; PATHOGENESIS; PEMPHIGUS FOLIACEUS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN POLYMORPHISM; STATISTICAL ANALYSIS; CASE CONTROL STUDY; ENDEMIC DISEASE; GENETIC PREDISPOSITION; GENETICS; PEMPHIGUS;

PEMPHIGUS;

ALLELES; CASE-CONTROL STUDIES; ENDEMIC DISEASES; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HLA-DR ANTIGENS; HUMANS; PEMPHIGUS;

EID: 0242281162     PISSN: 14664879     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gene.6363939     Document Type: Article

References (17)

1. Hans-Filho G, Aoki V, Rivitti E et al. Endemic pemphigus foliaceus (fogo selvagem) - 1998. Clin Dermatol 1999; 17: 225-235.
2. Petzl-Erler ML, Santamaria J. Are HLA class II genes controlling susceptibility and resistance to Brazilian pemphigus foliaceus (fogo selvagem)? Tissue Antigens 1989; 33: 408-414.
3. Moraes JR, Moraes ME, Fernandez-Viña M et al. HLA antigens and risk for development of pemphigus foliaceus (fogo selvagem) in endemic areas of Brazil. Immunogenetics 1991; 33: 388-391.
4. Cerna M, Fernandez-Viña M, Friedman H et al. Genetic markers for susceptibility to endemic Brazilian pemphigus foliaceus (fogo selvagem) in Xavante indians. Tissue Antigens 1993; 42: 138-140.
5. Moraes ME, Fernandez-Viña M, Lazaro A et al. An epitope in the third hypervariable region of the DRB1 gene is involved in the susceptibility to endemic pemphigus foliaceus (fogo selvagem) in three different Brazilian populations. Tissue Antigens 1997; 49: 35-40.
6. Ou D, Mitchell LA, Tingle AJ. A new categorization of HLA DR alleles on a functional basis. Hum Immunol 1998; 59: 665-676.
7. Paul C, Schoenwald U, Truckenbrodt H et al. HLA-DP/DR interaction in early pauciarticular juvenile chronic arthritis. Immunogenetics 1993; 37: 442-448.
8. Petzl-Erler ML, Gorodezky C, Layrisse Z et al. Anthropology Component Report for Region Latin-America: Amerindian and admixed populations. In Charron D (ed). Genetic Diversity of HLA. Functional and Medical Implications. EDK: Sèvres, 1997, pp 337-345.
9. Loiseau P, Lecleach L, Prost C et al. HLA class II polymorphism contributes to specify desmoglein derived peptides in pemphigus vulgaris and pemphigus foliaceus. J Autoimmun 2000; 15: 67-73.
10. Miyagawa S, Amagai M, Niizeki H et al. HLA-DRB1 polymorphisms and autoimmune responses to desmogleins in Japanese patients with pemphigus. Tissue Antigens 1999; 54: 333-340.
11. Cucca F, Lampis R, Frau F et al. The distribution of DR4 haplotypes in Sardinia suggests a primary association of type I diabetes with DRB1 and DQB1 loci. Hum Immunol 1995; 43: 301-308.
12. van der Horst-Bruinsma IE, Visser H, Hazes JM et al. HLA-DQ-associated predisposition to and dominant HLA-DR-associated protection against rheumatoid arthritis. Hum Immunol 1999; 60: 152-158.
13. Svejgaard A, Fugger L, Garred P et al. Association between HLA and disease with notes on additional association between a " new" immunogenetic marker and rheumatoid arthritis. In: Svejgaard A, Buus S, Fugger L (eds). HLA and Diseases - the Molecular Basis. Munksgaard: Copenhagen, 1997, pp 301-313.
14. Petzl-Erler ML. Genetics of the immune responses and disease susceptibility. Ciên Cult 1999; 51: 199-211.
15. Fernandez-Viña MA, Bignon JD. Primers and oligonucleotide probes (SSOP) used for DNA typing of HLA class II alleles. In: Charron D (ed). Genetic Diversity of HLA, Functional and Medical Implications. EDK: Paris, 1997, pp 596-632.
16. Miller MP. RxC: a program for the analyses of contingency tables via the Metropolis Algorithm. 1997. Computer software distributed by author.
17. Perneger TV. What's wrong with Bonferroni adjustments. BMJ 1998; 316: 1236-1238.