Evaluation of a line probe assay for identification of hepatitis B virus precore variants in serum from chronic hepatitis B carriers

Journal of Virological Methods

Volumn 114, Issue 1, 2003, Pages 97-103

  Cameron Wilson, Charlotte L ^a   Muir, Peter ^a,d   Ballard, Anna L ^b   Corden, Sally ^b,d   Boxall, Elizabeth H ^b   Sablon, Erwin ^c   Stuyver, Lieven ^c,e  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b BIRMINGHAM HEARTLANDS HOSPITAL   (United Kingdom)

^c INNOGENETICS   (Belgium)

^d PUBLIC HEALTH ENGLAND   (United Kingdom)

^e PHARMASSET INC   (United States)

Author keywords

Chronic hepatitis B; Line probe assay; Polymerase chain reaction; Precore variants

Indexed keywords

AMINO ACID; VIRUS DNA;

ARTICLE; BIOASSAY; BLOOD SAMPLING; CHRONIC HEPATITIS; CODON; CONTROLLED STUDY; GENE SEQUENCE; GENETIC ANALYSIS; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; MICROBIAL POPULATION DYNAMICS; NONHUMAN; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; VIRAL GENETICS; VIRUS CARRIER; VIRUS DETECTION; VIRUS GENE; VIRUS GENOME;

HEPATITIS B VIRUS;

EID: 0242268083     PISSN: 01660934     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jviromet.2003.09.014     Document Type: Article

References (29)

1. Alter H.J., Seeff L.B., Kaplan P.M., McAuliffe V.J., Wright E.C., Gerin J.L., Purcell R.H., Holland P.V., Zimmerman H.J. Type B hepatitis: the infectivity of blood positive for e antigen and DNA polymerase after accidental needlestick exposure. N. Engl. J. Med. 295:1976;909-913.
2. Ballard A.L., Boxall E.H. Colorimetric point mutation assay for detection of precore mutants of hepatitis B. J. Virol. Methods. 67:1997;143-152.
3. Ballard A.L., Boxall E.H. Assessing the infectivity of hepatitis B carriers. Commun. Dis. Public Health. 2:1999;178-183.
4. Ballard A.L., Boxall E.H. Epidemiology of precore mutants of hepatitis B in the United Kingdom. J. Med. Virol. 62:2000;463-470.
5. Baumert T.F., Rogers S.A., Hasegawa K., Liang T.J. Two core promoter mutations identified in hepatitis B virus strain associated with fulminant hepatitis result in enhanced replication. J. Clin. Invest. 98:1996;2268-2276.
6. Beasley R.P., Trepo C., Stevens C.E., Szmuness W. The e antigen and vertical transmission of hepatitis B surface antigen. Am. J. Epidemiol. 105:1977;94-98.
7. Boxall E.H., Peterson S., Diment J., Graham S.E., Shirley J.A. A novel assay for hepatitis B e markers. J. Med. Virol. 52:1997;280-285.
8. Brunetto M.R., Stemler M., Bonino F., Schodel F., Oliveri F., Rizzetto M., Verme G., Will H. A new hepatitis B virus strain in patients with severe anti-HBe positive chronic hepatitis. Br. J. Hepatol. 10:1991;258-261.
9. Buckwold V.E., Xu Z., Chen M., Yen T.S., Ou J.H. Effects of a naturally occurring mutation in the hepatitis B virus basal core promoter on precore gene expression and viral replication. J. Virol. 70:1996;5845-5851.
10. Carman W.F., Jacyna M.R., Hadziyannis S., Karayiannis P., McGarvey M., Makris A., Thomas H.C. Mutation preventing formation of e antigen in patients with chronic HBV infection. Lancet. 334:1989;588-591.
11. Casas I., Powell L., Klapper P.E., Cleator G.M. New method for extracting viral RNA and DNA from cerebrospinal fluid for use in polymerase chain reaction. J. Virol. Methods. 53:1995;25-36.
12. Fang Z.-L., Ling R., Wang S.S., Nong J., Huang C.S., Harrison T.J. HBV core promoter mutations prevail in patients with hepatocellular carcinoma from Guangxi, China. J. Med. Virol. 56:1998;18-24.
13. Grandjacques C., Pradat P., Stuyver L., Chevalier M., Chevalier P., Pichoud C., Maisonnas M., Trépo C., Zoulim F. Rapid detection of genotypes and mutations in the pre-core promoter and the pre-core region of hepatitis B virus genome: correlation with viral persistence and disease severity. J. Hepatol. 33:2000;430-439.
14. Günther S., Piwon N., Iwanska A., Schilling R., Meisel H., Will H. Type, prevalence and significance of core promoter/enhancer II mutations in hepatitis B viruses from immunosuppressed patients with severe liver disease. J. Virol. 70:1996;8318-8331.
15. Hawkins A.E., Gilson R.J.C., Beath S.V., Boxall E.H., Kelly D.A., Tedder R.S., Weller I.V.D. Novel application of a point mutation assay: evidence for transmission of hepatitis B viruses with precore mutations and their detection in infants with fulminant hepatitis B. J. Med. Virol. 44:1994;13-21.
16. Kramvis A., Kew M.C. The core promoter of hepatitis B virus. J. Viral Hepatitis. 6:1999;415-427.
17. Laras A., Koskinas J., Avgidis K., Hadziyannis S.J. Incidence and clinical significance of hepatitis B virus precore gene translation initiations in e antigen-negative patients. J. Viral Hepatitis. 5:1998;241-248.
18. Laskus T., Rakela J., Tong M.J., Nowicki M.J., Mosely J.W., Persing D.H. Naturally occurring hepatitis B virus mutants with deletions in the core promoter region. J. Hepatol. 20:1994;837-841.
19. Laskus T., Rakela J., Nowicki M.J., Persing D.H. Hepatitis B virus core promoter sequence analysis in fulminant and chronic hepatitis B. Gastroenterology. 109:1995;1618-1623.
20. Lok A.S., Akarca U., Greene S. Mutations in the pre-core region of hepatitis B virus serve to enhance the stability of the secondary structure of the pre-genome encapsidation signal. Proc. Natl. Acad. Sci. U.S.A. 91:1994;4077-4078.
21. Magnius L.O., Espmark A. A new antigen complex co-occurring with Australia antigen. Acta Pathol. Microbiol. Scand. Sect. B: Microbiol. Immunol. 80:1972;335-357.
22. Okamoto H., Tsuda F., Akahane Y., Sugai Y., Yoshiba M., Moriyama K., Tanaka T., Miyakawa Y., Mayumi M. Hepatitis B virus with mutations in the core promoter for an e antigen negative in carriers with antibody to e antigen. J. Virol. 68:1994;8102-8110.
23. Santantonio T., Jung M.-C., Schneider R., Pastore G., Pape G.R., Will H. Selection for a pre-C stop codon mutation in a hepatitis B virus variant with a pre-C initiation codon mutation during interferon treatment. J. Hepatol. 3:1991;368-371.
24. Stuyver L., Rossau R., Wyseur A., Duhamel M., Vanderborght B., van Heuverswyn H., Maertens G. Typing of hepatitis C virus isolates and characterization of new subtypes using a line probe assay. J. Gen. Virol. 74:1993;1093-1102.
25. Stuyver L., Wyseur A., van Arnheim W., Hernandez F., Maertens G. Second generation line probe assay for hepatitis C virus genotyping. J. Clin. Microbiol. 34:1996;2259-2266.
26. Stuyver L., Wyseur A., Rombout A., Louwagie J., Scarcez T., Verhofstede C., Rimland D., Schinazi R.F., Rossau R. Line probe assay for rapid detection of drug-selected mutations in the human immunodeficiency virus type 1 reverse transcriptase gene. Antimicrob. Agents Chemother. 41:1997;284-291.
27. Stuyver L., De Gendt S., Cadranel J.F., Van Geyt C., Van Reybroek G., Dorent R., Gandjbachkh I., Rosenheim M., Charlotte F., Opolon P., Huraux J.M., Lunel F. Three cases of severe subfulminant hepatitis in heart transplanted patients after nosocomial transmission of a mutant hepatitis B virus. Hepatology. 29:1999;1876-1883.
28. Stuyver L., Van Geyt C., De Gendt S., Van Reybroeck G., Zoulim F., Leroux-Roels G., Rossau R. Line probe assay for monitoring drug resistance in hepatitis B virus-infected patients during antiviral therapy. J. Clin. Microbiol. 38:2000;702-707.
29. The Incident Investigation Team and Others, 1997. Transmission of hepatitis B to patients from four infected surgeons without hepatitis B e antigen. N. Engl. J. Med. 336, 178-184.