The COP1-SPA1 interaction defines a critical step in phytochrome A-mediated regulation of HY5 activity

Genes and Development

Volumn 17, Issue 21, 2003, Pages 2642-2647

  Saijo, Yusuke ^a   Sullivan, James A ^a   Wang, Haiyang ^b   Yang, Jianping ^b   Shen, Yunping ^a   Rubio, Vicente ^a   Ma, Ligeng ^a   Hoecker, Ute ^c   Deng, Xing Wang ^a  

^a YALE UNIVERSITY   (United States)

^b United States Department of Agriculture Agricultural Research Service and Boyce Thompson Institute for Plant Research   (United States)

^c HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Arabidopsis; Photomorphogenesis; Phytochrome; Protein complex; Protein degradation; Ubiquitination

Indexed keywords

COMPLEMENTARY DNA; HY5 PROTEIN; HYBRID PROTEIN; MESSENGER RNA; PHYTOCHROME; PHYTOCHROME A; PROTEASOME; REPRESSOR PROTEIN; SPA1 PROTEIN; TRANSCRIPTION FACTOR; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE COP1; UNCLASSIFIED DRUG;

ARABIDOPSIS; ARTICLE; ENZYME ACTIVITY; IMMUNOPRECIPITATION; MORPHOGENESIS; NONHUMAN; PHOTORECEPTOR; PLANT GROWTH; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; TRANSGENIC PLANT; WESTERN BLOTTING; YEAST;

ARABIDOPSIS; ARABIDOPSIS PROTEINS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; NUCLEAR PROTEINS; PHYTOCHROME; PHYTOCHROME A; UBIQUITIN-PROTEIN LIGASES;

ARABIDOPSIS;

EID: 0242266958     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.1122903     Document Type: Article

References (19)

1. Ballesteros, M.L., Bolle, C., Lois, L.M., Moore, J.M., Vielle-Calzada, J.P., Grossniklaus, U., and Chua, N.H. 2001. LAF1: A MYB transcriptional activator for phytochrome A signaling. Genes & Dev. 15: 2613-2625.
2. β homologous domain. Cell 71: 791-801.
3. Hajdukiewicz, P., Svab, Z., and Maliga, P. 1994. The small, versatile pPZP family of Agrobacterium binary vectors for plant transformation. Plant Mol. Biol. 25: 989-994.
4. Hardtke, C.S., Okamoto, H., Stoop-Myer, C., and Deng, X.W. 2002. Biochemical evidence for ubiquitin ligase activity of the Arabidopsis COP1 interacting protein 8 (CIP8). Plant J. 30: 385-394.
5. Hoecker, U. and Quail, P.H. 2001. The phytochrome A-specific signaling intermediate SPA1 interacts directly with COP1, a constitutive repressor of light signaling in Arabidopsis. J. Biol. Chem. 276: 38173-38178.
6. Hoecker, U., Tepperman, J.M., and Quail, P.H. 1999. SPA1: A WD-repeat protein specific to phytochrome A signal transduction. Science 284: 496-499.
7. Holm, M., Hardtke, C.S., Gaudet, R., and Deng, X.W. 2001. Identification of a structural motif that confers specific interaction with the WD40 repeat domain of Arabidopsis COP1. EMBO J. 20: 118-127.
8. McNellis, T.W., von Arnim, A.G., Araki, T., Komeda, Y., Misera, S., and Deng, X.W. 1994. Genetic and molecular analysis of an allelic series of cop1 mutants suggests functional roles for the multiple protein domains. Plant Cell 6: 487-500.
9. Osterlund, M.T., Hardtke, C.S., Wei, N., and Deng, X.W. 2000. Targeted destabilization of HY5 during light-regulated development of Arabidopsis. Nature 405: 462-466.
10. Oyama, T., Shimura, Y., and Okada, K. 1997. The Arabidopsis HY5 gene encodes a bZIP protein that regulates stimulus-induced development of root and hypocotyl. Genes & Dev. 11, 2983-2995.
11. Pickart, C.M. 2001. Mechanisms underlying ubiquitination. Annu. Rev. Biochem. 70: 503-533.
12. Rigaut, G., Shevchenko, A., Rutz, B., Wilm, M., Mann, M., and Seraphin, B. 1999. A genetic protein purification method for protein complex characterization and proteome exploration. Nat. Biotech. 17: 1030-1032.
13. Seo, S.H., Yang, J., Ishikawa, M., Bolle, B., Ballesteros, M.L., and Chua, N.H. 2003. LAF1 ubiquination by COP1 controls photomorphogenesis and is stimulated by SPA1. Nature 423: 995-999.
14. Suzuki, G., Yanagawa, Y., Kwok, S.F., Matsui, M., and Deng, X.W. 2002. Arabidopsis COP10 is a ubiquitin-conjugating enzyme variant that acts together with COP1 and the COP9 signalosome in repressing photomorphogenesis. Genes & Dev. 16: 554-559.
15. Torii, K.U., McNellis, W., and Deng, X.W. 1998. Functional dissection of Arabidopsis COP1 reveals specific roles of its three structural modules in light control of seedling development. EMBO J. 17: 5577-5587.
16. Torii, K.U., Stoop-Myer, C.D., Okamoto, H., Coleman, J.E., Matsui, M., and Deng, X.W. 1999. The RING finger motif of photomorphogenic repressor COP1 specifically interacts with the RING-H2 motif of a novel Arabidopsis protein. J. Biol. Chem. 274: 27674-27681.
17. Wang, H. and Deng, X.W. 2002. Phytochrome signaling mechanism. In The Arabidopsis book (eds. C.R. Somerville and E.M. Meyerowitz). American Society of Plant Biologists, Rockville, MD; doi/10.1199/ tab.0074, http://www.aspb.org/publications/arabidopsis (published electronically).
18. Wang, H., Ma, L.-G., Li, J.-M., Zhao, H.-Y., and Deng, X.W. 2001. Direct interaction of Arabidopsis cryptochromes with COP1 in light control development. Science 294: 154-158.
19. Wang, H., Ma, L.-G., Habashi, J., Li, J., Zhao, H., and Deng, X.W. 2002. Analysis of far-red light-regulated genome expression profiles of phytochrome A pathway mutants in Arabidopsis. Plant J. 32: 723-733.