High iron and low ascorbic acid concentrations in the dermis of atopic dermatitis patients

Dermatology

Volumn 207, Issue 3, 2003, Pages 261-264

  Leveque, Nathalie ^a   Robin, Sophie ^a   Muret, Patrice ^a   Mac Mary, Sophie ^a   Makki, Safwat ^a   Humbert, Philippe ^a,b  

^a UNIVERSITÉ DE FRANCHE COMTÉ   (France)

^b HÔPITAL SAINT JACQUES   (France)

Author keywords

Ascorbic acid; Atomic absorption spectrometry; Atopic dermatitis; Iron; Mass spectrometry; Microdialysis

Indexed keywords

ASCORBIC ACID; IRON;

ADULT; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; ATOPIC DERMATITIS; CLINICAL ARTICLE; CONTROLLED STUDY; DERMOEPIDERMAL JUNCTION; DISEASE MARKER; GAS CHROMATOGRAPHY; HUMAN; INTERMETHOD COMPARISON; IRON BLOOD LEVEL; MEDICAL ASSESSMENT; MICRODIALYSIS; PRIORITY JOURNAL; VITAMIN BLOOD LEVEL;

ADULT; ASCORBIC ACID; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; DERMATITIS, ATOPIC; DERMIS; FEMALE; HUMANS; IRON; MALE; MIDDLE AGED; PROBABILITY; PROGNOSIS; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; STATISTICS, NONPARAMETRIC;

EID: 0142258883     PISSN: 10188665     EISSN: None     Source Type: Journal    
DOI: 10.1159/000073087     Document Type: Article

References (21)

1. Buettner GR, Jurkiewicz BA: Catalytic metals, ascorbate and free radicals: Combinations to avoid. Radiat Res 1996;145:532-541.
2. Trenam CW, Blake D, Morris CJ: Skin inflammation: Reactive oxygen species and the role of iron. J Invest Dermatol 1992;99:675-682.
3. Morris C, Earl J, Trenam C, Blake D: Reactive oxygen species and iron. A dangerous partnership in inflammation. Int J Biochem Cell Biol 1995;27:109-122.
4. Conrad ME, Umbreit JN, Moore EG: Iron absorption and transport. Am J Med Sci 1999;318:213-229.
5. Simonart T, Van Vooren JP, Parent D, Heenen M, Boelaert JR: Role of iron in dermatology. Dermatology 2000;200:156-159.
6. Shindo Y, Wiit E, Han D, Epstein W, Packer L: Enzymatic and non-enzymatic antioxidant in epidermis and dermis of human skin. J Invest Dermatol 1994;102:122-124.
7. Leveque N, Robin S, Makki S, Muret P, Mary S, Berthelot A, Humbert P: Iron concentrations in human dermis assessed by microdialysis associated with atomic absorption spectrometry. Biol Pharm Bull 2001;24:10-13.
8. Leveque N, Mary S, Makki S, Muret P, Kantelip JP, Humbert P: Ascorbic acid assessment in human dermis by a microdialysis technique associated with gas chromatography - mass spectrometry. Eur J Mass Spectrom 2000;6:397-404.
9. Vernet M: Exploration du statut martial. Rev Prat 2000;50:950-955.
10. Benzie IFF: Vitamin C: Prospective functional markers for defining optimal nutritional status. Proc Nutr Soc 1999;58:469-476.
11. Forslind B, Werner-Linde Y, Lindberg M, Pallon J: Elemental analysis mirrors epidermal differentiation. Ann Derm Venereol (Stockh) 1999;79:12-17.
12. Kaur S, Zilmer M, Eisen M, Kullisaar T, Rehema A, Vihalemm T: Patients with allergic and irritant contact dermatitis are characterized by striking change of iron and oxidized gluthatione status in nonlesional area of the skin. J Invest Dermatol 2001;116:886-890.
13. Bissett D, Chatterjee R, Hannon D: Chronic ultraviolet radiation-induced increase in skin iron and the photoprotective effect of topically applied iron chelators. Photochem Photobiol 1991;54:211-214.
14. Shahabiddinov TT, Shadiev HK, Ibragimov UK: New aspects of atopic dermatitis pathogenesis. J Eur Acad Dermatol Venereol 1997;9:S217.
15. Matés JM, Pérez-Goméz C, Blanca M: Chemical and biological activity of free radical 'scavengers' in allergic diseases. Clin Chim Acta 2000;296:1-15.
16. Schwager J, Schulze J: Modulation of interleukin production by ascorbic acid. Vet Immunol Immunopathol 1998;64:45-57.
17. Bissett DL, Chatterjee R, Hannon DP: Photo-protective effect of superoxide-scavenging antioxidants against ultraviolet radiation-induced chronic skin damage in the hairless mouse. Photodermatol Photoimmunol Photomed 1990;7:56-62.
18. Antille C, Sorg O, Lübbe J, Saurat JH: Decreased oxidative state in non-lesional skin of atopic dermatitis. Dermatology 2002;204:69-71.
19. Solvoll K, Søyland E, Sandstad B, Drevon CA: Dietary habits among patients with atopic dermatitis. Eur J Clin Nutr 2000;54:93-97.
20. arth GA, Weigl L, Boeing H, Disch R, Dorelli S: Food intake of patients with atopic dermatitis. Eur J Dermatol 2001;11:199-202.
21. Leveque N, Robin S, Muret P, Mary S, Makki S, Berthelot A, Kantelip JP, Humbert P: In vivo assessment of ascorbic acid and iron in psoriatic patient dermis. A new approach by microdialysis. Acta Derm Venereol, in press.