Role of hemin in the modulation of H2O2-mediated endothelial cell injury

Vascular Pharmacology

Volumn 40, Issue 2, 2003, Pages 109-118

  Wilson, Stephen J ^a   Keenan, Alan K ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Cytotoxicity; Endothelial cells; Heme oxygenase 1; Hemin; Hydrogen peroxide; Permeability

Indexed keywords

ENZYME; HEME OXYGENASE 1; HEMIN; HYDROGEN PEROXIDE; PROTOPORPHYRIN;

AORTA; ARTICLE; CATTLE; CELL CULTURE; CELL LINE; CELL MEMBRANE PERMEABILITY; CELL PROTECTION; CELL VIABILITY; CONCENTRATION RESPONSE; CULTURE MEDIUM; CYTOTOXICITY; ENDOTHELIUM INJURY; HUMAN; HUMAN CELL; INCUBATION TIME; MODULATION; MONOLAYER CULTURE; OXIDATIVE STRESS; PRIORITY JOURNAL; STRESS; UMBILICAL VEIN; VASCULAR ENDOTHELIUM; WESTERN BLOTTING;

EID: 0142227764     PISSN: 15371891     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1537-1891(02)00340-3     Document Type: Article

References (29)

1. Aft R.L., Mueller G.C. Hemin-mediated oxidative degradation of proteins. J. Biol. Chem. 259:1984;301-305.
2. Amit Y., Boneh A. Bilirubin inhibits protein kinase C activity and protein kinase C-mediated phosphorylation of endogenous substrates in human skin fibroblasts. Clin. Chim. Acta. 223:1993;103-111.
3. Balla J., Jacob H.S., Balla G., Nath K., Eaton J.W., Vercellotti G.M. Endothelial-cell heme uptake from heme proteins: induction of sensitization and desensitization to oxidant damage. Proc. Natl. Acad. Sci. USA. 90:1993;9285-9289.
4. Baranano D.E., Snyder S.H. Neural roles for heme oxygenase: contrasts to nitric oxide synthase. Proc. Natl. Acad. Sci. USA. 98:2001;10996-11002.
5. Benjamin I.J., McMillan D.R. Stress (heat shock) proteins: molecular chaperones in cardiovascular biology and disease. Circ. Res. 83:1998;117-132.
6. Buchan K.W., Martin W. Modulation of barrier function of bovine aortic and pulmonary artery endothelial cells: dissociation from cytosolic calcium content. Br. J. Pharmacol. 107:1992;932-938.
7. Burke-Gaffney A., Keenan A.K. Modulation of human endothelial cell permeability by combinations of the cytokines interleukin-1 α/β, tumor necrosis factor-α and interferon-γ Immunopharmacology. 25:1993;1-9.
8. Clark J.E., Foresti R., Green C.J., Motterlini R. Dynamics of haem oxygenase-1 expression and bilirubin production in cellular protection against oxidative stress. Biochem. J. 348:2000;615-619.
9. Cullen V.C., Mackarel A.J., Hislip S.J., O'Connor C.M., Keenan A.K. Investigation of vascular endothelial growth factor effects on pulmonary endothelial monolayer permeability and neutrophil transmigration. Gen. Pharmacol. 35:2000;149-157.
10. Draijer R., Atsma D.E., van der Laarse A., van Hinsbergh V.W. cGMP and nitric oxide modulate thrombin-induced endothelial permeability. Regulation via different pathways in human aortic and umbilical vein endothelial cells. Circ. Res. 76:1995;199-208.
11. Gille J.J., Joenje H. Cell culture models for oxidative stress: superoxide and hydrogen peroxide versus normobaric hyperoxia. Mutat. Res. 275:1992;405-414.
12. Gutteridge J.M., Smith A. Antioxidant protection by haemopexin of haem-stimulated lipid peroxidation. Biochem. J. 256:1988;861-865.
13. Huang F.P., Xi G., Keep R.F., Hua Y., Nemoianu A., Hoff J.T. Brain edema after experimental intracerebral hemorrhage: role of hemoglobin degradation products. J. Neurosurg. 96:2002;287-293.
14. Juckett M., Zheng Y., Yuan H., Pastor T., Antholine W., Weber M., Vercellotti G. Heme and the endothelium. Effects of nitric oxide on catalytic iron and heme degradation by heme oxygenase. J. Biol. Chem. 273:1998;23388- 23397.
15. Kevil C.G., Ohno N., Gute D.C., Okayama N., Robinson S.A., Chaney E., Alexander J.S. Role of cadherin internalization in hydrogen peroxide-mediated endothelial permeability. Free Radic. Biol. Med. 24:1998;1015-1022.
16. McQuaid K.E., Smyth E.M., Keenan A.K. Evidence for modulation of hydrogen peroxide-induced endothelial barrier dysfunction by nitric oxide in vitro. Eur. J. Pharmacol. 307:1996;233-241.
17. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods. 65:1983;55-63.
18. Motterlini R., Foresti R., Intaglietta M., Winslow R.M. NO-mediated activation of heme oxygenase: endogenous cytoprotection against oxidative stress to endothelium. Am. J. Physiol. 270:1996;H107-H114.
19. Motterlini R., Foresti R., Bassi R., Calabrese V., Clark J.E., Green C.J. Endothelial heme oxygenase-1 induction by hypoxia. Modulation by inducible nitric-oxide synthase and S-nitrosothiols. J. Biol. Chem. 275:2000;13613-13620.
20. Rotrosen D., Gallin J.I. Histamine type I receptor occupancy increases endothelial cytosolic calcium, reduces F-actin, and promotes albumin diffusion across cultured endothelial monolayers. J. Cell Biol. 103:1986;2379-23787.
21. Ryter S.W., Tyrrell R.M. The heme synthesis and degradation pathways: role in oxidant sensitivity. Heme oxygenase has both pro- and antioxidant properties. Free Radic. Biol. Med. 28:2000;289-309.
22. Shasby D.M., Lind S.E., Shasby S.S., Goldsmith J.C., Hunninghake G.W. Reversible oxidant-induced increases in albumin transfer across cultured endothelium: alterations in cell shape and calcium homeostasis. Blood. 65:1985;605-614.
23. Siflinger-Birnboim A., Goligorsky M.S., Del Vecchio P.J., Malik A.B. Activation of protein kinase C pathway contributes to hydrogen peroxide-induced increase in endothelial permeability. Lab. Invest. 67:1992;24-30.
24. Suliman H.B., Carraway M.S., Velsor L.W., Day B.J., Ghio A.J., Piantadosi C.A. Rapid mtDNA deletion by oxidants in rat liver mitochondria after hemin exposure. Free Radic. Biol. Med. 32:2002;246-256.
25. Suttorp N., Hippenstiel S., Fuhrmann M., Krull M., Podzuweit T. Role of nitric oxide and phosphodiesterase isoenzyme II for reduction of endothelial hyperpermeability. Am. J. Physiol. 270:1996;C778-C785.
26. Yachie A., Niida Y., Wada T., Igarashi N., Kaneda H., Toma T., Ohta K., Kasahara Y., Koizumi S. Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency. J. Clin. Invest. 103:1999;129-135.
27. Yamada N., Yamaya M., Okinaga S., Lie R., Suzuki T., Nakayama K., Takeda A., Yamaguchi T., Itoyama Y., Sekizawa K., Sasaki H. Protective effects of heme oxygenase-1 against oxidant-induced injury in the cultured human tracheal epithelium. Am. J. Respir. Cell Mol. Biol. 21:1999;428-435.
28. Yang L., Quan S., Abraham N.G. Retrovirus-mediated HO gene transfer into endothelial cells protects against oxidant-induced injury. Am. J. Physiol. 277:1999;L127-L133.
29. Yet S.F., Perella M.A., Layne M.D., Hsieh C.M., Maemura K., Kobzik L., Wiesel P., Christou H., Kourembanas S., Lee M.E. Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase null mice. J. Clin. Invest. 103:1999;23-29.