메뉴 건너뛰기




Volumn 9, Issue 13, 2003, Pages 4972-4982

Exisulind and Related Compounds Inhibit Expression and Function of the Androgen Receptor in Human Prostate Cancer Cells

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; CP 248; CP 461; LUCIFERASE; PROSTAGLANDIN SYNTHASE; PROSTATE SPECIFIC ANTIGEN; PROTEIN BCL 2; PROTEIN P53; SULINDAC SULFIDE; SULINDAC SULFONE; UNCLASSIFIED DRUG;

EID: 0142219316     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (25)

References (38)
  • 2
    • 0032569926 scopus 로고    scopus 로고
    • The androgen receptor CAG repeat polymorphism and its relationship to prostate cancer
    • Kantoff, P., Giovannucci, E., and Brown, M. The androgen receptor CAG repeat polymorphism and its relationship to prostate cancer. Biochim. Biophys. Acta, 1378: C1-C5, 1998.
    • (1998) Biochim. Biophys. Acta , vol.1378
    • Kantoff, P.1    Giovannucci, E.2    Brown, M.3
  • 3
    • 0023913120 scopus 로고
    • The steroid and thyroid hormone receptor superfamily
    • Evans, R. M. The steroid and thyroid hormone receptor superfamily. Science (Wash. DC), 240: 889-895, 1988.
    • (1988) Science (Wash. DC) , vol.240 , pp. 889-895
    • Evans, R.M.1
  • 6
    • 0030000662 scopus 로고    scopus 로고
    • Genetic basis and clonal evolution of human prostate cancer
    • Kallioniemi, O. P., and Visakorpi, T. Genetic basis and clonal evolution of human prostate cancer. Adv. Cancer Res., 68: 225-255, 1996.
    • (1996) Adv. Cancer Res. , vol.68 , pp. 225-255
    • Kallioniemi, O.P.1    Visakorpi, T.2
  • 7
    • 0032949624 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs inhibit the expression of cytokines and induce HSP70 in human monocytes
    • Housby, J. N., Cahill, C. M., Chu, B., Prevelige, R., Bickford, K., Stevenson, M. A., and Calderwood, S. K. Non-steroidal anti-inflammatory drugs inhibit the expression of cytokines and induce HSP70 in human monocytes. Cytokine, 11: 347-358, 1999.
    • (1999) Cytokine , vol.11 , pp. 347-358
    • Housby, J.N.1    Cahill, C.M.2    Chu, B.3    Prevelige, R.4    Bickford, K.5    Stevenson, M.A.6    Calderwood, S.K.7
  • 8
    • 0034234978 scopus 로고    scopus 로고
    • Exisulind induction of apoptosis involves guanosine 3′, 5′-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated β-catenin
    • Thompson, W. J., Piazza, G. A., Li, H., Liu, L., Fetter, J., Zhu, B., Sperl, G., Ahnen, D., and Pamukcu, R. Exisulind induction of apoptosis involves guanosine 3′, 5′-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated β-catenin. Cancer Res., 60: 3338-3342, 2000.
    • (2000) Cancer Res. , vol.60 , pp. 3338-3342
    • Thompson, W.J.1    Piazza, G.A.2    Li, H.3    Liu, L.4    Fetter, J.5    Zhu, B.6    Sperl, G.7    Ahnen, D.8    Pamukcu, R.9
  • 11
    • 0009413722 scopus 로고    scopus 로고
    • Down-regulation of prostate-specific antigen expression by finasteride through inhibition of complex formation between androgen receptor and steroid receptor-binding consensus in the promoter of the PSA gene in LNCaP cells
    • Wang, L. G., Liu, X. M., Kreis, W., and Budman, D. R. Down-regulation of prostate-specific antigen expression by finasteride through inhibition of complex formation between androgen receptor and steroid receptor-binding consensus in the promoter of the PSA gene in LNCaP cells. Cancer Res., 57: 714-719, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 714-719
    • Wang, L.G.1    Liu, X.M.2    Kreis, W.3    Budman, D.R.4
  • 12
    • 0031944598 scopus 로고    scopus 로고
    • Cyclin D1 expression in human prostate carcinoma cell lines and primary tumors
    • Han, E. K., Lim, J. T., Arber, N., Rubin, M. A., Xing, W. Q., and Weinstein, I. B. Cyclin D1 expression in human prostate carcinoma cell lines and primary tumors. Prostate, 35: 95-101, 1998.
    • (1998) Prostate , vol.35 , pp. 95-101
    • Han, E.K.1    Lim, J.T.2    Arber, N.3    Rubin, M.A.4    Xing, W.Q.5    Weinstein, I.B.6
  • 14
    • 0031397434 scopus 로고    scopus 로고
    • The palliative therapy of advanced prostate cancer, with particular reference to the results of recent European clinical trials
    • Newling, D. W. The palliative therapy of advanced prostate cancer. with particular reference to the results of recent European clinical trials. Br J. Urol., 79 (Suppl. 1): 72-81, 1997.
    • (1997) Br J. Urol. , vol.79 , Issue.SUPPL. 1 , pp. 72-81
    • Newling, D.W.1
  • 15
    • 0030925135 scopus 로고    scopus 로고
    • Second-line treatment of metastatic prostatic carcinoma
    • Newling, D. W. Second-line treatment of metastatic prostatic carcinoma. Urol. Res., 25 (Suppl. 2): S73-S78, 1997.
    • (1997) Urol. Res. , vol.25 , Issue.SUPPL. 2
    • Newling, D.W.1
  • 17
    • 0021083826 scopus 로고
    • Characterization and cloning of rat dorsal prostate mRNAs
    • Dodd, J., Sheppard, P., and Matusik, R. Characterization and cloning of rat dorsal prostate mRNAs. J. Biol. Chem., 258: 10731-10737, 1983.
    • (1983) J. Biol. Chem. , vol.258 , pp. 10731-10737
    • Dodd, J.1    Sheppard, P.2    Matusik, R.3
  • 18
    • 0030669869 scopus 로고    scopus 로고
    • Chromosomal localization, structure, and regulation of the UGT2B17 gene, encoding a C19 steroid metabolizing enzyme
    • Beaulieu, M., Levesque, E., Tchernof, A., Beatty, B. G., Belanger, A., and Hum, D. W. Chromosomal localization, structure, and regulation of the UGT2B17 gene, encoding a C19 steroid metabolizing enzyme. DNA Cell Biol., 16: 1143-1154, 1997.
    • (1997) DNA Cell Biol. , vol.16 , pp. 1143-1154
    • Beaulieu, M.1    Levesque, E.2    Tchernof, A.3    Beatty, B.G.4    Belanger, A.5    Hum, D.W.6
  • 19
    • 0036189484 scopus 로고    scopus 로고
    • Development of two androgen receptor assays using adenoviral transduction of MMTV-luc reporter and/or hAR for endocrine screening
    • Hartig, P. C., Bobseine, K. L., Britt, B. H., Cardon, M. C., Lambright, C. R., Wilson, V. S., and Gray, L. E., Jr. Development of two androgen receptor assays using adenoviral transduction of MMTV-luc reporter and/or hAR for endocrine screening. Toxicol. Sci., 66: 82-90, 2002.
    • (2002) Toxicol. Sci. , vol.66 , pp. 82-90
    • Hartig, P.C.1    Bobseine, K.L.2    Britt, B.H.3    Cardon, M.C.4    Lambright, C.R.5    Wilson, V.S.6    Gray L.E., Jr.7
  • 20
    • 0036192083 scopus 로고    scopus 로고
    • A novel cell line, MDA-kb2, that stably expresses an androgen- and glucocorticoid-responsive reporter for the detection of hormone receptor agonists and antagonists
    • Wilson, V. S., Bobseine, K., Lambright, C. R., and Gray, L. E., Jr. A novel cell line, MDA-kb2, that stably expresses an androgen- and glucocorticoid-responsive reporter for the detection of hormone receptor agonists and antagonists. Toxicol. Sci., 66: 69-81, 2002.
    • (2002) Toxicol. Sci. , vol.66 , pp. 69-81
    • Wilson, V.S.1    Bobseine, K.2    Lambright, C.R.3    Gray L.E., Jr.4
  • 21
    • 0026591729 scopus 로고
    • Anti-androgens and the mutated androgen receptor of LNCaP cells: Differential effects on binding affinity, heat-shock protein interaction, and transcription activation
    • Veldscholte, J., Berrevoets, C. A., Brinkmann, A. O., Grootegoed, J. A., and Mulder, E. Anti-androgens and the mutated androgen receptor of LNCaP cells: differential effects on binding affinity, heat-shock protein interaction, and transcription activation. Biochemistry, 31: 2393-2399, 1992.
    • (1992) Biochemistry , vol.31 , pp. 2393-2399
    • Veldscholte, J.1    Berrevoets, C.A.2    Brinkmann, A.O.3    Grootegoed, J.A.4    Mulder, E.5
  • 22
    • 0028107468 scopus 로고
    • Identification of 3′, 5′-cyclic adenosine monophosphate response element and other cis-acting elements in the human androgen receptor gene promoter
    • Mizokami, A., Yeh, S. Y., and Chang, C. Identification of 3′, 5′-cyclic adenosine monophosphate response element and other cis-acting elements in the human androgen receptor gene promoter. Mol. Endocrinol., 8: 77-88, 1994.
    • (1994) Mol. Endocrinol. , vol.8 , pp. 77-88
    • Mizokami, A.1    Yeh, S.Y.2    Chang, C.3
  • 23
    • 0035056548 scopus 로고    scopus 로고
    • Transactivation of AP-1 in AP-1-luciferase reporter transgenic mice by arsenite and arsenate
    • Huang, C., Bode, A. M., Chen, N. Y., Ma, W. Y., Li, J., Nomura, M., and Dong, Z. Transactivation of AP-1 in AP-1-luciferase reporter transgenic mice by arsenite and arsenate. Anticancer Res., 21: 261-267, 2001.
    • (2001) Anticancer Res. , vol.21 , pp. 261-267
    • Huang, C.1    Bode, A.M.2    Chen, N.Y.3    Ma, W.Y.4    Li, J.5    Nomura, M.6    Dong, Z.7
  • 24
    • 0033755261 scopus 로고    scopus 로고
    • Cyclic GMP mediates apoptosis induced by sulindac derivatives via activation of e-Jun NH2-terminal kinase 1
    • Soh, J. W., Mao, Y., Kim, M. G., Pamukcu, R., Li, H., Piazza, G. A., Thompson, W. J., and Weinstein, I. B. Cyclic GMP mediates apoptosis induced by sulindac derivatives via activation of e-Jun NH2-terminal kinase 1. Clin. Cancer Res., 6: 4136-4141, 2000.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 4136-4141
    • Soh, J.W.1    Mao, Y.2    Kim, M.G.3    Pamukcu, R.4    Li, H.5    Piazza, G.A.6    Thompson, W.J.7    Weinstein, I.B.8
  • 26
    • 0033119603 scopus 로고    scopus 로고
    • Identification of the transcriptional regulatory sequences of human kallikrein 2 and their use in the construction of calydon virus 764, an attenuated replication competent adenovirus for prostate cancer therapy
    • Yu, D. C., Sakamoto, G. T., and Henderson, D. R. Identification of the transcriptional regulatory sequences of human kallikrein 2 and their use in the construction of calydon virus 764, an attenuated replication competent adenovirus for prostate cancer therapy. Cancer Res., 59: 1498-1504, 1999.
    • (1999) Cancer Res. , vol.59 , pp. 1498-1504
    • Yu, D.C.1    Sakamoto, G.T.2    Henderson, D.R.3
  • 27
    • 0030841919 scopus 로고    scopus 로고
    • Androgenic induction of prostate-specific antigen gene is repressed by protein-protein interaction between the androgen receptor and AP-1/c-Jun in the human prostate cancer cell line LNCaP
    • Sato, N., Sadar, M. D., Bruchovsky, N., Saatcioglu, F., Rennie, P. S., Sato, S., Lange, P. H., and Gleave, M. E. Androgenic induction of prostate-specific antigen gene is repressed by protein-protein interaction between the androgen receptor and AP-1/c-Jun in the human prostate cancer cell line LNCaP. J. Biol. Chem., 272: 17485-17494, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 17485-17494
    • Sato, N.1    Sadar, M.D.2    Bruchovsky, N.3    Saatcioglu, F.4    Rennie, P.S.5    Sato, S.6    Lange, P.H.7    Gleave, M.E.8
  • 28
    • 0033583317 scopus 로고    scopus 로고
    • Androgen-independent induction of prostate-specific antigen gene expression via cross-talk between the androgen receptor and protein kinase A signal transduction pathways
    • Sadar, M. D. Androgen-independent induction of prostate-specific antigen gene expression via cross-talk between the androgen receptor and protein kinase A signal transduction pathways. J. Biol. Chem., 274: 7777-7783, 1999.
    • (1999) J. Biol. Chem. , vol.274 , pp. 7777-7783
    • Sadar, M.D.1
  • 29
    • 0035844219 scopus 로고    scopus 로고
    • Protein kinase G activates the JNKI pathway via phosphorylation of MEKK1
    • Soh, J. W., Mao, Y., Liu, L., Thompson, W. J., Pamukcu, R., and Weinstein, I. B. Protein kinase G activates the JNKI pathway via phosphorylation of MEKK1. J. Biol. Chem., 276: 16406-16410, 2001.
    • (2001) J. Biol. Chem. , vol.276 , pp. 16406-16410
    • Soh, J.W.1    Mao, Y.2    Liu, L.3    Thompson, W.J.4    Pamukcu, R.5    Weinstein, I.B.6
  • 31
    • 0033303818 scopus 로고    scopus 로고
    • A nonsteroidal anti-inflammatory drug, flufenamic acid, inhibits the expression of the androgen receptor in LNCaP cells
    • Zhu, W., Smith, A., and Young, C. Y. A nonsteroidal anti-inflammatory drug, flufenamic acid, inhibits the expression of the androgen receptor in LNCaP cells. Endocrinology, 140: 5451-5454, 1999.
    • (1999) Endocrinology , vol.140 , pp. 5451-5454
    • Zhu, W.1    Smith, A.2    Young, C.Y.3
  • 32
    • 0029888978 scopus 로고    scopus 로고
    • Suramin-induced decrease in prostate-specific antigen expression with no effect on tumor growth in the LNCaP model of human prostate cancer
    • Thalmann, G. N., Sikes, R. A., Chang, S. M., Johnston, D. A., von Eschenbach, A. C., and Chung, L. W. Suramin-induced decrease in prostate-specific antigen expression with no effect on tumor growth in the LNCaP model of human prostate cancer [see comments]. J. Natl. Cancer Inst. (Bethesda), 88: 794-801, 1996.
    • (1996) J. Natl. Cancer Inst. (Bethesda) , vol.88 , pp. 794-801
    • Thalmann, G.N.1    Sikes, R.A.2    Chang, S.M.3    Johnston, D.A.4    Von Eschenbach, A.C.5    Chung, L.W.6
  • 36
    • 4243598283 scopus 로고    scopus 로고
    • Selective apoptosis of neoplastic cells accompanies polyp regression in familial adenomatous poplyposis (FAP) patients treated with FGN-I (sulindac sulfone): Evidence for a cyclooxygenase independent mechanism
    • Piazza, G. A., Fryer, B. H., Stolk, R. U. v., Budd, G. T., Stoner, G. D., Hawk, E., Kelloff, G., Pamukcu, R., Ahnen, D. J., and Ganapathi, R. Selective apoptosis of neoplastic cells accompanies polyp regression in familial adenomatous poplyposis (FAP) patients treated with FGN-I (sulindac sulfone): evidence for a cyclooxygenase independent mechanism. Gastroenterology, A-283, 1997.
    • (1997) Gastroenterology
    • Piazza, G.A.1    Fryer, B.H.2    Stolk, R.U.V.3    Budd, G.T.4    Stoner, G.D.5    Hawk, E.6    Kelloff, G.7    Pamukcu, R.8    Ahnen, D.J.9    Ganapathi, R.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.